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Enhanced single-cell RNA-seq workflow reveals coronary artery disease cellular cross-talk and candidate drug targets.
Ma WF, Hodonsky CJ, Turner AW, Wong D, Song Y, Mosquera JV, Ligay AV, Slenders L, Gancayco C, Pan H, Barrientos NB, Mai D, Alencar GF, Owsiany K, Owens GK, Reilly MP, Li M, Pasterkamp G, Mokry M, van der Laan SW, Khomtchouk BB, Miller CL. Ma WF, et al. Among authors: mokry m. Atherosclerosis. 2022 Jan;340:12-22. doi: 10.1016/j.atherosclerosis.2021.11.025. Epub 2021 Nov 26. Atherosclerosis. 2022. PMID: 34871816 Free PMC article.
Additional Candidate Genes for Human Atherosclerotic Disease Identified Through Annotation Based on Chromatin Organization.
Haitjema S, Meddens CA, van der Laan SW, Kofink D, Harakalova M, Tragante V, Foroughi Asl H, van Setten J, Brandt MM, Bis JC, O'Donnell C, Cheng C, Hoefer IE, Waltenberger J, Biessen E, Jukema JW, Doevendans PA, Nieuwenhuis EE, Erdmann J, Björkegren JL, Pasterkamp G, Asselbergs FW, den Ruijter HM, Mokry M. Haitjema S, et al. Among authors: mokry m. Circ Cardiovasc Genet. 2017 Apr;10(2):e001664. doi: 10.1161/CIRCGENETICS.116.001664. Circ Cardiovasc Genet. 2017. PMID: 28320757 Free article.
Smoking is Associated to DNA Methylation in Atherosclerotic Carotid Lesions.
Siemelink MA, van der Laan SW, Haitjema S, van Koeverden ID, Schaap J, Wesseling M, de Jager SCA, Mokry M, van Iterson M, Dekkers KF, Luijk R, Foroughi Asl H, Michoel T, Björkegren JLM, Aavik E, Ylä-Herttuala S, de Borst GJ, Asselbergs FW, El Azzouzi H, den Ruijter HM, Heijmans BT, Pasterkamp G. Siemelink MA, et al. Among authors: mokry m. Circ Genom Precis Med. 2018 Sep;11(9):e002030. doi: 10.1161/CIRCGEN.117.002030. Circ Genom Precis Med. 2018. PMID: 30354327
Genetic Susceptibility Loci for Cardiovascular Disease and Their Impact on Atherosclerotic Plaques.
van der Laan SW, Siemelink MA, Haitjema S, Foroughi Asl H, Perisic L, Mokry M, van Setten J, Malik R, Dichgans M, Worrall BB; METASTROKE Collaboration of the International Stroke Genetics Consortium; Samani NJ, Schunkert H, Erdmann J, Hedin U, Paulsson-Berne G, Björkegrenn JLM, de Borst GJ, Asselbergs FW, den Ruijter FW, de Bakker PIW, Pasterkamp G. van der Laan SW, et al. Among authors: mokry m. Circ Genom Precis Med. 2018 Sep;11(9):e002115. doi: 10.1161/CIRCGEN.118.002115. Circ Genom Precis Med. 2018. PMID: 30354329 Free PMC article.
Platelet RNA modules point to coronary calcification in asymptomatic women with former preeclampsia.
Hartman RJG, Korporaal SJA, Mokry M, de Jager SCA, Meeuwsen JAL, van der Laan SW, Lansu NR, Zoet GA, Pasterkamp G, Urbanus RT, Hoefer IE, Franx A, Velthuis BK, van Rijn BB, den Ruijter HM; Queen of Hearts and CREW consortia. Hartman RJG, et al. Among authors: mokry m. Atherosclerosis. 2019 Dec;291:114-121. doi: 10.1016/j.atherosclerosis.2019.10.009. Epub 2019 Oct 11. Atherosclerosis. 2019. PMID: 31706077
Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis.
Alencar GF, Owsiany KM, Karnewar S, Sukhavasi K, Mocci G, Nguyen AT, Williams CM, Shamsuzzaman S, Mokry M, Henderson CA, Haskins R, Baylis RA, Finn AV, McNamara CA, Zunder ER, Venkata V, Pasterkamp G, Björkegren J, Bekiranov S, Owens GK. Alencar GF, et al. Among authors: mokry m. Circulation. 2020 Nov 24;142(21):2045-2059. doi: 10.1161/CIRCULATIONAHA.120.046672. Epub 2020 Jul 17. Circulation. 2020. PMID: 32674599 Free PMC article.
Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics.
Depuydt MAC, Prange KHM, Slenders L, Örd T, Elbersen D, Boltjes A, de Jager SCA, Asselbergs FW, de Borst GJ, Aavik E, Lönnberg T, Lutgens E, Glass CK, den Ruijter HM, Kaikkonen MU, Bot I, Slütter B, van der Laan SW, Yla-Herttuala S, Mokry M, Kuiper J, de Winther MPJ, Pasterkamp G. Depuydt MAC, et al. Among authors: mokry m. Circ Res. 2020 Nov 6;127(11):1437-1455. doi: 10.1161/CIRCRESAHA.120.316770. Epub 2020 Sep 28. Circ Res. 2020. PMID: 32981416 Free PMC article.
Functional investigation of the coronary artery disease gene SVEP1.
Winkler MJ, Müller P, Sharifi AM, Wobst J, Winter H, Mokry M, Ma L, van der Laan SW, Pang S, Miritsch B, Hinterdobler J, Werner J, Stiller B, Güldener U, Webb TR, Asselbergs FW, Björkegren JLM, Maegdefessel L, Schunkert H, Sager HB, Kessler T. Winkler MJ, et al. Among authors: mokry m. Basic Res Cardiol. 2020 Nov 13;115(6):67. doi: 10.1007/s00395-020-00828-6. Basic Res Cardiol. 2020. PMID: 33185739 Free PMC article.
Sex-Stratified Gene Regulatory Networks Reveal Female Key Driver Genes of Atherosclerosis Involved in Smooth Muscle Cell Phenotype Switching.
Hartman RJG, Owsiany K, Ma L, Koplev S, Hao K, Slenders L, Civelek M, Mokry M, Kovacic JC, Pasterkamp G, Owens G, Björkegren JLM, den Ruijter HM. Hartman RJG, et al. Among authors: mokry m. Circulation. 2021 Feb 16;143(7):713-726. doi: 10.1161/CIRCULATIONAHA.120.051231. Epub 2021 Jan 27. Circulation. 2021. PMID: 33499648 Free PMC article.
199 results