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Molecular Characterization of a Patient's Small Cell Carcinoma of the Ovary of the Hypercalcemic Type.
Stephens B, Anthony SP, Han H, Kiefer J, Hostetter G, Barrett M, Von Hoff DD. Stephens B, et al. J Cancer. 2012;3:58-66. doi: 10.7150/jca.3872. Epub 2012 Jan 26. J Cancer. 2012. PMID: 22315651 Free PMC article.
Small cell carcinoma of the ovary of the hypercalcemic type (SCCOHT) is a very rare tumor type that mainly affects young women. ...Upon relapse, the patient underwent total abdominal hysterectomy, followed by chemotherapy with gemcitabine. ...
Small cell carcinoma of the ovary of the hypercalcemic type (SCCOHT) is a very rare tumor type that mainly affec …
Invasive Lobular Carcinoma.
Handelsman R, Tomlinson-Hansen SE. Handelsman R, et al. 2026 Apr 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. 2026 Apr 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. PMID: 32119465 Free Books & Documents.
A defining molecular feature involves mutation of the CDH1 gene in more than 90% of cases, leading to loss of E-cadherin, a protein essential for cell-to-cell adhesion. ...Unique tumor biology also drives metastasis to atypical sites, including the gastrointe …
A defining molecular feature involves mutation of the CDH1 gene in more than 90% of cases, leading to loss of E-cadherin, a protein e …
A Population-Based Study of Patients With Small Cell Carcinoma of the Ovary, Hypercalcemic Type, Encompassing a 30-Year Period.
Blatnik A, Dragoš VŠ, Blatnik O, Stegel V, Klančar G, Novaković S, Drev P, Žagar T, Merlo S, Škof E, Bojadžiski MP, Strojnik K, Krajc M. Blatnik A, et al. Arch Pathol Lab Med. 2024 Mar 1;148(3):299-309. doi: 10.5858/arpa.2022-0297-OA. Arch Pathol Lab Med. 2024. PMID: 37270804 Free article.
CONTEXT.-: Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare and lethal tumor, characterized by hypercalcemia and early onset and associated with germline and somatic SMARCA4 variants. ...Outcomes were poor, with 6 of 7 …
CONTEXT.-: Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare and lethal tumor, charact …
Establishment and characterization of a novel cell line (SCCOHT-CH-1) and PDX models derived from Chinese patients of small cell ovarian carcinoma of the hypercalcemic type.
Gao Y, Zheng K, Kang M, Xu J, Ning Y, Hu W, Li K, Kang Y, Xu C. Gao Y, et al. Hum Cell. 2023 Nov;36(6):2214-2227. doi: 10.1007/s13577-023-00966-8. Epub 2023 Aug 3. Hum Cell. 2023. PMID: 37535222 Free PMC article.
Small cell carcinoma of the ovary hypercalcemic type (SCCOHT) is a rare and aggressive malignancy that poses a significant clinical challenge due to its grim prognosis. Unfortunately, only three SCCOHT cell lines are currently available for scie …
Small cell carcinoma of the ovary hypercalcemic type (SCCOHT) is a rare and aggressive malignancy that poses a s …
MicroRNA and Metabolic Profiling of a Primary Ovarian Neuroendocrine Carcinoma Pulmonary-Type Reveals a High Degree of Similarity with Small Cell Lung Cancer.
Miglietta S, Girolimetti G, Marchio L, Sollazzo M, Laprovitera N, Coluccelli S, De Biase D, De Leo A, Santini D, Kurelac I, Iommarini L, Ghelli A, Campana D, Ferracin M, Perrone AM, Gasparre G, Porcelli AM. Miglietta S, et al. Noncoding RNA. 2022 Sep 25;8(5):64. doi: 10.3390/ncrna8050064. Noncoding RNA. 2022. PMID: 36287116 Free PMC article.
Small cell neuroendocrine carcinoma is most frequently found in the lung (SCLC), but it has been also reported, albeit with a very low incidence, in the ovary. Here, we analyze a case of primary small cell carcinoma of the ovary …
Small cell neuroendocrine carcinoma is most frequently found in the lung (SCLC), but it has been also reported, albeit …
Clinicopathological and molecular characteristics of small cell carcinoma of the ovary, hypercalcemic type: three case reports.
Jiang W, Li S, Peng Y, Xiao J, Wang D, Chen C, Zhang Y, Zhang C, Fu C. Jiang W, et al. Discov Oncol. 2026 Apr 5;17(1):757. doi: 10.1007/s12672-026-04844-1. Discov Oncol. 2026. PMID: 41935983 Free PMC article.
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT), is a rare and aggressive ovarian cancer that affects populations ranging from children to young adults. ...Two patients were initially misdiagnosed with adult granulosa cell …
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT), is a rare and aggressive ovarian cancer that aff …
Antitumor effects of interleukin-6 (IL-6)/interleukin-6 receptor (IL-6R) signaling pathway inhibition in clear cell carcinoma of the ovary.
Yanaihara N, Hirata Y, Yamaguchi N, Noguchi Y, Saito M, Nagata C, Takakura S, Yamada K, Okamoto A. Yanaihara N, et al. Mol Carcinog. 2016 May;55(5):832-41. doi: 10.1002/mc.22325. Epub 2015 Apr 9. Mol Carcinog. 2016. PMID: 25856562
Among epithelial ovarian cancers, clear cell carcinoma of the ovary (CCC) has unique clinical and molecular characteristics that include chemoresistance resulting in poor prognosis. It was shown that CCC recently was characterized by specific up …
Among epithelial ovarian cancers, clear cell carcinoma of the ovary (CCC) has unique clinical and molecular char …
SMARCA4-deficient undifferentiated carcinoma of the ovary (small cell carcinoma, hypercalcemic type): clinicopathologic and immunohistochemical study of 3 cases.
Agaimy A, Thiel F, Hartmann A, Fukunaga M. Agaimy A, et al. Ann Diagn Pathol. 2015 Oct;19(5):283-7. doi: 10.1016/j.anndiagpath.2015.06.001. Epub 2015 Jun 9. Ann Diagn Pathol. 2015. PMID: 26123103
Small cell carcinoma of the ovary, hypercalcemic type is a very rare aggressive neoplasm of unknown histogenesis, affecting mainly girls and young women. ...Nuclear SMARCB1 was intact in all cases (1 case showed small foci with mosaic loss). All …
Small cell carcinoma of the ovary, hypercalcemic type is a very rare aggressive neoplasm of unknown histogenesis …
Desmoplastic small cell tumor in the pancreas.
Bismar TA, Basturk O, Gerald WL, Schwarz K, Adsay NV. Bismar TA, et al. Am J Surg Pathol. 2004 Jun;28(6):808-12. doi: 10.1097/01.pas.0000126782.94781.dc. Am J Surg Pathol. 2004. PMID: 15166674
Desmoplastic small cell tumor (DSCT) is a distinct type of small blue cell tumors and is characterized by the unique karyotypic aberration involving the fusion of the Ewing's sarcoma (EWS) gene and Wilms' tumor (WT1) gene. ...This case shows tha …
Desmoplastic small cell tumor (DSCT) is a distinct type of small blue cell tumors and is characterized by …
Decoding NADPH oxidase 4 expression in human tumors.
Meitzler JL, Makhlouf HR, Antony S, Wu Y, Butcher D, Jiang G, Juhasz A, Lu J, Dahan I, Jansen-Dürr P, Pircher H, Shah AM, Roy K, Doroshow JH. Meitzler JL, et al. Redox Biol. 2017 Oct;13:182-195. doi: 10.1016/j.redox.2017.05.016. Epub 2017 May 26. Redox Biol. 2017. PMID: 28578276 Free PMC article.
Most studies of NOX4 in malignancy have focused on the evaluation of a small number of tumor cell lines and not on human tumor specimens themselves; furthermore, these studies have often employed immunological tools that have not been well characterized. ...E …
Most studies of NOX4 in malignancy have focused on the evaluation of a small number of tumor cell lines and not on human tumor …
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