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SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells.
Hammer Q, Dunst J, Christ W, Picarazzi F, Wendorff M, Momayyezi P, Huhn O, Netskar HK, Maleki KT, García M, Sekine T, Sohlberg E, Azzimato V, Aouadi M; Karolinska COVID-19 Study Group; Severe COVID-19 GWAS Group; Degenhardt F, Franke A, Spallotta F, Mori M, Michaëlsson J, Björkström NK, Rückert T, Romagnani C, Horowitz A, Klingström J, Ljunggren HG, Malmberg KJ. Hammer Q, et al. Among authors: momayyezi p. Cell Rep. 2022 Mar 8;38(10):110503. doi: 10.1016/j.celrep.2022.110503. Epub 2022 Feb 21. Cell Rep. 2022. PMID: 35235832 Free PMC article.
An optimized platform for efficient siRNA delivery into human NK cells.
Palacios D, Momayyezi P, Huhn O, Ask EH, Dunst J, Malmberg KJ, Hammer Q. Palacios D, et al. Among authors: momayyezi p. Eur J Immunol. 2022 Jul;52(7):1190-1193. doi: 10.1002/eji.202149710. Epub 2022 Apr 22. Eur J Immunol. 2022. PMID: 35416292 Free PMC article.
Genetic ablation of adhesion ligands averts rejection of allogeneic immune cells.
Hammer Q, Perica K, van Ooijen H, Mbofung R, Momayyezi P, Varady E, Martin KE, Pan Y, Jelcic M, Groff B, Abujarour R, Krokeide S, Lee T, Williams A, Goodridge JP, Valamehr B, Önfelt B, Sadelain M, Malmberg KJ. Hammer Q, et al. Among authors: momayyezi p. bioRxiv [Preprint]. 2023 Oct 9:2023.10.09.557143. doi: 10.1101/2023.10.09.557143. bioRxiv. 2023. PMID: 37873468 Free PMC article. Preprint.
Adaptive single-KIR+NKG2C+ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia.
Haroun-Izquierdo A, Vincenti M, Netskar H, van Ooijen H, Zhang B, Bendzick L, Kanaya M, Momayyezi P, Li S, Wiiger MT, Hoel HJ, Krokeide SZ, Kremer V, Tjonnfjord G, Berggren S, Wikström K, Blomberg P, Alici E, Felices M, Önfelt B, Höglund P, Valamehr B, Ljunggren HG, Björklund A, Hammer Q, Kveberg L, Cichocki F, Miller JS, Malmberg KJ, Sohlberg E. Haroun-Izquierdo A, et al. Among authors: momayyezi p. J Immunother Cancer. 2022 Nov;10(11):e005577. doi: 10.1136/jitc-2022-005577. J Immunother Cancer. 2022. PMID: 36319065 Free PMC article.