Monfregola J - Search Results

1

MUNC13-4 protein regulates the oxidative response and is essential for phagosomal maturation and bacterial killing in neutrophils.

Monfregola J, Johnson JL, Meijler MM, Napolitano G, Catz SD. Monfregola J, et al. J Biol Chem. 2012 Dec 28;287(53):44603-18. doi: 10.1074/jbc.M112.414029. Epub 2012 Oct 31. J Biol Chem. 2012. PMID: 23115246 Free PMC article.

2

Functional characterization of Wiskott-Aldrich syndrome protein and scar homolog (WASH), a bi-modular nucleation-promoting factor able to interact with biogenesis of lysosome-related organelle subunit 2 (BLOS2) and gamma-tubulin.

Monfregola J, Napolitano G, D'Urso M, Lappalainen P, Ursini MV. Monfregola J, et al. J Biol Chem. 2010 May 28;285(22):16951-7. doi: 10.1074/jbc.M109.078501. Epub 2010 Mar 22. J Biol Chem. 2010. PMID: 20308062 Free PMC article.

3

Munc13-4 restricts motility of Rab27a-expressing vesicles to facilitate lipopolysaccharide-induced priming of exocytosis in neutrophils.

Johnson JL, Hong H, Monfregola J, Kiosses WB, Catz SD. Johnson JL, et al. Among authors: monfregola j. J Biol Chem. 2011 Feb 18;286(7):5647-56. doi: 10.1074/jbc.M110.184762. Epub 2010 Dec 9. J Biol Chem. 2011. PMID: 21148308 Free PMC article.

4

Increased survival and reduced neutrophil infiltration of the liver in Rab27a- but not Munc13-4-deficient mice in lipopolysaccharide-induced systemic inflammation.

Johnson JL, Hong H, Monfregola J, Catz SD. Johnson JL, et al. Among authors: monfregola j. Infect Immun. 2011 Sep;79(9):3607-18. doi: 10.1128/IAI.05043-11. Epub 2011 Jul 11. Infect Immun. 2011. PMID: 21746860 Free PMC article.

5

Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein.

Johnson JL, Monfregola J, Napolitano G, Kiosses WB, Catz SD. Johnson JL, et al. Among authors: monfregola j. Mol Biol Cell. 2012 May;23(10):1902-16. doi: 10.1091/mbc.E11-12-1001. Epub 2012 Mar 21. Mol Biol Cell. 2012. PMID: 22438581 Free PMC article.

6

Upregulation of the Rab27a-dependent trafficking and secretory mechanisms improves lysosomal transport, alleviates endoplasmic reticulum stress, and reduces lysosome overload in cystinosis.

Johnson JL, Napolitano G, Monfregola J, Rocca CJ, Cherqui S, Catz SD. Johnson JL, et al. Among authors: monfregola j. Mol Cell Biol. 2013 Aug;33(15):2950-62. doi: 10.1128/MCB.00417-13. Epub 2013 May 28. Mol Cell Biol. 2013. PMID: 23716592 Free PMC article.

7

Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis.

Napolitano G, Johnson JL, He J, Rocca CJ, Monfregola J, Pestonjamasp K, Cherqui S, Catz SD. Napolitano G, et al. Among authors: monfregola j. EMBO Mol Med. 2015 Feb;7(2):158-74. doi: 10.15252/emmm.201404223. EMBO Mol Med. 2015. PMID: 25586965 Free PMC article.

8

Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses.

He J, Johnson JL, Monfregola J, Ramadass M, Pestonjamasp K, Napolitano G, Zhang J, Catz SD. He J, et al. Among authors: monfregola j. Mol Biol Cell. 2016 Feb 1;27(3):572-87. doi: 10.1091/mbc.E15-05-0283. Epub 2015 Dec 17. Mol Biol Cell. 2016. PMID: 26680738 Free PMC article.

9

mTOR-dependent phosphorylation controls TFEB nuclear export.

Napolitano G, Esposito A, Choi H, Matarese M, Benedetti V, Di Malta C, Monfregola J, Medina DL, Lippincott-Schwartz J, Ballabio A. Napolitano G, et al. Among authors: monfregola j. Nat Commun. 2018 Aug 17;9(1):3312. doi: 10.1038/s41467-018-05862-6. Nat Commun. 2018. PMID: 30120233 Free PMC article.

10

A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome.

Napolitano G, Di Malta C, Esposito A, de Araujo MEG, Pece S, Bertalot G, Matarese M, Benedetti V, Zampelli A, Stasyk T, Siciliano D, Venuta A, Cesana M, Vilardo C, Nusco E, Monfregola J, Calcagnì A, Di Fiore PP, Huber LA, Ballabio A. Napolitano G, et al. Among authors: monfregola j. Nature. 2020 Sep;585(7826):597-602. doi: 10.1038/s41586-020-2444-0. Epub 2020 Jul 1. Nature. 2020. PMID: 32612235 Free PMC article.

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