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Monitoring in real time the cytotoxic effect of Clostridium difficile upon the intestinal epithelial cell line HT29.
Valdés L, Gueimonde M, Ruas-Madiedo P. Valdés L, et al. J Microbiol Methods. 2015 Dec;119:66-73. doi: 10.1016/j.mimet.2015.09.022. Epub 2015 Oct 5. J Microbiol Methods. 2015. PMID: 26436983
In this regard, the lack of fast and reliable in vitro screening methods to search for novel anti-toxin drugs has hampered this approach. The aim of the current study was to develop a method to monitor in real time the cytotoxicity of C. difficile
In this regard, the lack of fast and reliable in vitro screening methods to search for novel anti-toxin drugs has hampered this approach. Th …
Screening of Bifidobacteria and Lactobacilli Able to Antagonize the Cytotoxic Effect of Clostridium difficile upon Intestinal Epithelial HT29 Monolayer.
Valdés-Varela L, Alonso-Guervos M, García-Suárez O, Gueimonde M, Ruas-Madiedo P. Valdés-Varela L, et al. Front Microbiol. 2016 Apr 22;7:577. doi: 10.3389/fmicb.2016.00577. eCollection 2016. Front Microbiol. 2016. PMID: 27148250 Free PMC article.
Several novel intervention strategies against CDI are currently under study, such as the use of probiotics to counteract the growth and/or toxigenic activity of C. difficile. In this work, we have analyzed the capability of twenty Bifidobacterium and Lactobacillus strains, …
Several novel intervention strategies against CDI are currently under study, such as the use of probiotics to counteract the growth and/or t …