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A soluble activin receptor type IIb prevents the effects of androgen deprivation on body composition and bone health.
Endocrinology. 2010 Sep;151(9):4289-300. doi: 10.1210/en.2010-0134. Epub 2010 Jun 23.
Endocrinology. 2010.
PMID: 20573726
Characterization of the ligand binding functionality of the extracellular domain of activin receptor type IIb.
Sako D, Grinberg AV, Liu J, Davies MV, Castonguay R, Maniatis S, Andreucci AJ, Pobre EG, Tomkinson KN, Monnell TE, Ucran JA, Martinez-Hackert E, Pearsall RS, Underwood KW, Seehra J, Kumar R.
Sako D, et al. Among authors: monnell te.
J Biol Chem. 2010 Jul 2;285(27):21037-48. doi: 10.1074/jbc.M110.114959. Epub 2010 Apr 12.
J Biol Chem. 2010.
PMID: 20385559
Free PMC article.
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Administration of a soluble activin type IIB receptor promotes skeletal muscle growth independent of fiber type.
Cadena SM, Tomkinson KN, Monnell TE, Spaits MS, Kumar R, Underwood KW, Pearsall RS, Lachey JL.
Cadena SM, et al. Among authors: monnell te.
J Appl Physiol (1985). 2010 Sep;109(3):635-42. doi: 10.1152/japplphysiol.00866.2009. Epub 2010 May 13.
J Appl Physiol (1985). 2010.
PMID: 20466801
Free PMC article.
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Treatment with a soluble receptor for activin improves bone mass and structure in the axial and appendicular skeleton of female cynomolgus macaques (Macaca fascicularis).
Fajardo RJ, Manoharan RK, Pearsall RS, Davies MV, Marvell T, Monnell TE, Ucran JA, Pearsall AE, Khanzode D, Kumar R, Underwood KW, Roberts B, Seehra J, Bouxsein ML.
Fajardo RJ, et al. Among authors: monnell te.
Bone. 2010 Jan;46(1):64-71. doi: 10.1016/j.bone.2009.09.018. Epub 2009 Sep 23.
Bone. 2010.
PMID: 19781677
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A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys.
Lotinun S, Pearsall RS, Davies MV, Marvell TH, Monnell TE, Ucran J, Fajardo RJ, Kumar R, Underwood KW, Seehra J, Bouxsein ML, Baron R.
Lotinun S, et al. Among authors: monnell te.
Bone. 2010 Apr;46(4):1082-8. doi: 10.1016/j.bone.2010.01.370. Epub 2010 Jan 18.
Bone. 2010.
PMID: 20080223
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ALK1-Fc inhibits multiple mediators of angiogenesis and suppresses tumor growth.
Mitchell D, Pobre EG, Mulivor AW, Grinberg AV, Castonguay R, Monnell TE, Solban N, Ucran JA, Pearsall RS, Underwood KW, Seehra J, Kumar R.
Mitchell D, et al. Among authors: monnell te.
Mol Cancer Ther. 2010 Feb;9(2):379-88. doi: 10.1158/1535-7163.MCT-09-0650. Epub 2010 Feb 2.
Mol Cancer Ther. 2010.
PMID: 20124460
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Efficient specification of interneurons from human pluripotent stem cells by dorsoventral and rostrocaudal modulation.
Kim TG, Yao R, Monnell T, Cho JH, Vasudevan A, Koh A, Peeyush KT, Moon M, Datta D, Bolshakov VY, Kim KS, Chung S.
Kim TG, et al. Among authors: monnell t.
Stem Cells. 2014 Jul;32(7):1789-804. doi: 10.1002/stem.1704.
Stem Cells. 2014.
PMID: 24648391
Free PMC article.
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