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A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic.
Shapira T, Monreal IA, Dion SP, Buchholz DW, Imbiakha B, Olmstead AD, Jager M, Désilets A, Gao G, Martins M, Vandal T, Thompson CAH, Chin A, Rees WD, Steiner T, Nabi IR, Marsault E, Sahler J, Diel DG, Van de Walle GR, August A, Whittaker GR, Boudreault PL, Leduc R, Aguilar HC, Jean F. Shapira T, et al. Among authors: monreal ia. Nature. 2022 May;605(7909):340-348. doi: 10.1038/s41586-022-04661-w. Epub 2022 Mar 28. Nature. 2022. PMID: 35344983 Free PMC article.
Antivirals targeting paramyxovirus membrane fusion.
Contreras EM, Monreal IA, Ruvalcaba M, Ortega V, Aguilar HC. Contreras EM, et al. Among authors: monreal ia. Curr Opin Virol. 2021 Dec;51:34-47. doi: 10.1016/j.coviro.2021.09.003. Epub 2021 Sep 27. Curr Opin Virol. 2021. PMID: 34592709 Free PMC article. Review.
Multivalent viral particles elicit safe and efficient immunoprotection against Nipah Hendra and Ebola viruses.
Ithinji DG, Buchholz DW, Ezzatpour S, Monreal IA, Cong Y, Sahler J, Bangar AS, Imbiakha B, Upadhye V, Liang J, Ma A, Bradel-Tretheway B, Kaza B, Yeo YY, Choi EJ, Johnston GP, Huzella L, Kollins E, Dixit S, Yu S, Postnikova E, Ortega V, August A, Holbrook MR, Aguilar HC. Ithinji DG, et al. Among authors: monreal ia. NPJ Vaccines. 2022 Dec 17;7(1):166. doi: 10.1038/s41541-022-00588-5. NPJ Vaccines. 2022. PMID: 36528644 Free PMC article.
Adaptive immune cells are necessary for SARS-CoV-2-induced pathology.
Imbiakha B, Sahler JM, Buchholz DW, Ezzatpour S, Jager M, Choi A, Monreal IA, Byun H, Adeleke RA, Leach J, Whittaker G, Dewhurst S, Rudd BD, Aguilar HC, August A. Imbiakha B, et al. Among authors: monreal ia. Sci Adv. 2024 Jan 5;10(1):eadg5461. doi: 10.1126/sciadv.adg5461. Epub 2024 Jan 3. Sci Adv. 2024. PMID: 38170764 Free PMC article.
23 results