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Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling.
Keune WJ, Hausmann J, Bolier R, Tolenaars D, Kremer A, Heidebrecht T, Joosten RP, Sunkara M, Morris AJ, Matas-Rico E, Moolenaar WH, Oude Elferink RP, Perrakis A. Keune WJ, et al. Among authors: moolenaar wh. Nat Commun. 2016 Apr 14;7:11248. doi: 10.1038/ncomms11248. Nat Commun. 2016. PMID: 27075612 Free PMC article.
Lysophosphatidic acid is a potential mediator of cholestatic pruritus.
Kremer AE, Martens JJ, Kulik W, Ruëff F, Kuiper EM, van Buuren HR, van Erpecum KJ, Kondrackiene J, Prieto J, Rust C, Geenes VL, Williamson C, Moolenaar WH, Beuers U, Oude Elferink RP. Kremer AE, et al. Among authors: moolenaar wh. Gastroenterology. 2010 Sep;139(3):1008-18, 1018.e1. doi: 10.1053/j.gastro.2010.05.009. Epub 2010 Jun 19. Gastroenterology. 2010. PMID: 20546739
Autotaxin: structure-function and signaling.
Perrakis A, Moolenaar WH. Perrakis A, et al. Among authors: moolenaar wh. J Lipid Res. 2014 Jun;55(6):1010-8. doi: 10.1194/jlr.R046391. Epub 2014 Feb 18. J Lipid Res. 2014. PMID: 24548887 Free PMC article. Review.
Autotaxin and LPA receptor signaling in cancer.
Houben AJ, Moolenaar WH. Houben AJ, et al. Among authors: moolenaar wh. Cancer Metastasis Rev. 2011 Dec;30(3-4):557-65. doi: 10.1007/s10555-011-9319-7. Cancer Metastasis Rev. 2011. PMID: 22002750 Review.
Inhibition of RhoA-mediated SRF activation by p116Rip.
Mulder J, Ariaens A, van Horck FP, Moolenaar WH. Mulder J, et al. Among authors: moolenaar wh. FEBS Lett. 2005 Nov 7;579(27):6121-7. doi: 10.1016/j.febslet.2005.09.083. Epub 2005 Oct 13. FEBS Lett. 2005. PMID: 16243315
Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate.
van Meeteren LA, Ruurs P, Christodoulou E, Goding JW, Takakusa H, Kikuchi K, Perrakis A, Nagano T, Moolenaar WH. van Meeteren LA, et al. Among authors: moolenaar wh. J Biol Chem. 2005 Jun 3;280(22):21155-61. doi: 10.1074/jbc.M413183200. Epub 2005 Mar 15. J Biol Chem. 2005. PMID: 15769751
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