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Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling.
Keune WJ, Hausmann J, Bolier R, Tolenaars D, Kremer A, Heidebrecht T, Joosten RP, Sunkara M, Morris AJ, Matas-Rico E, Moolenaar WH, Oude Elferink RP, Perrakis A. Keune WJ, et al. Among authors: moolenaar wh. Nat Commun. 2016 Apr 14;7:11248. doi: 10.1038/ncomms11248. Nat Commun. 2016. PMID: 27075612 Free PMC article.
Autotaxin in embryonic development.
Moolenaar WH, Houben AJ, Lee SJ, van Meeteren LA. Moolenaar WH, et al. Biochim Biophys Acta. 2013 Jan;1831(1):13-9. doi: 10.1016/j.bbalip.2012.09.013. Epub 2012 Sep 28. Biochim Biophys Acta. 2013. PMID: 23022664 Review.
Lysophosphatidic acid is a potential mediator of cholestatic pruritus.
Kremer AE, Martens JJ, Kulik W, Ruëff F, Kuiper EM, van Buuren HR, van Erpecum KJ, Kondrackiene J, Prieto J, Rust C, Geenes VL, Williamson C, Moolenaar WH, Beuers U, Oude Elferink RP. Kremer AE, et al. Among authors: moolenaar wh. Gastroenterology. 2010 Sep;139(3):1008-18, 1018.e1. doi: 10.1053/j.gastro.2010.05.009. Epub 2010 Jun 19. Gastroenterology. 2010. PMID: 20546739
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