Mooney MH - Search Results

1

Improved stability, insulin-releasing activity and antidiabetic potential of two novel N-terminal analogues of gastric inhibitory polypeptide: N-acetyl-GIP and pGlu-GIP.

O'Harte FP, Gault VA, Parker JC, Harriott P, Mooney MH, Bailey CJ, Flatt PR. O'Harte FP, et al. Among authors: mooney mh. Diabetologia. 2002 Sep;45(9):1281-91. doi: 10.1007/s00125-002-0894-6. Epub 2002 Jul 16. Diabetologia. 2002. PMID: 12242461

2

Enhanced cAMP generation and insulin-releasing potency of two novel Tyr1-modified enzyme-resistant forms of glucose-dependent insulinotropic polypeptide is associated with significant antihyperglycaemic activity in spontaneous obesity-diabetes.

Gault VA, Flatt PR, Bailey CJ, Harriott P, Greer B, Mooney MH, O'harte FP. Gault VA, et al. Among authors: mooney mh. Biochem J. 2002 Nov 1;367(Pt 3):913-20. doi: 10.1042/BJ20020319. Biochem J. 2002. PMID: 12150711 Free PMC article.

3

Metabolic stability, receptor binding, cAMP generation, insulin secretion and antihyperglycaemic activity of novel N-terminal Glu9-substituted analogues of glucagon-like peptide-1.

Green BD, Gault VA, Irwin N, Mooney MH, Bailey CJ, Harriott P, Greer B, Flatt PR, O'Harte FP. Green BD, et al. Among authors: mooney mh. Biol Chem. 2003 Dec;384(12):1543-51. doi: 10.1515/BC.2003.171. Biol Chem. 2003. PMID: 14719796

4

Degradation, receptor binding, insulin secreting and antihyperglycaemic actions of palmitate-derivatised native and Ala8-substituted GLP-1 analogues.

Green BD, Gault VA, Mooney MH, Irwin N, Harriott P, Greer B, Bailey CJ, O'Harte FP, Flatt PR. Green BD, et al. Among authors: mooney mh. Biol Chem. 2004 Feb;385(2):169-77. doi: 10.1515/BC.2004.035. Biol Chem. 2004. PMID: 15101559

5

A novel, long-acting agonist of glucose-dependent insulinotropic polypeptide suitable for once-daily administration in type 2 diabetes.

Irwin N, Green BD, Mooney MH, Greer B, Harriott P, Bailey CJ, Gault VA, O'Harte FP, Flatt PR. Irwin N, et al. Among authors: mooney mh. J Pharmacol Exp Ther. 2005 Sep;314(3):1187-94. doi: 10.1124/jpet.105.086082. Epub 2005 May 27. J Pharmacol Exp Ther. 2005. PMID: 15923344

6

NH2-terminally modified gastric inhibitory polypeptide exhibits amino-peptidase resistance and enhanced antihyperglycemic activity.

O'Harte FP, Mooney MH, Flatt PR. O'Harte FP, et al. Among authors: mooney mh. Diabetes. 1999 Apr;48(4):758-65. doi: 10.2337/diabetes.48.4.758. Diabetes. 1999. PMID: 10102692

7

Improved glycaemic control in obese diabetic ob/ob mice using N-terminally modified gastric inhibitory polypeptide.

O'Harte FP, Mooney MH, Kelly CM, Flatt PR. O'Harte FP, et al. Among authors: mooney mh. J Endocrinol. 2000 Jun;165(3):639-48. doi: 10.1677/joe.0.1650639. J Endocrinol. 2000. PMID: 10828847

8

Evaluation of glycated insulin in diabetic animals using immunocytochemistry and radioimmunoassay.

McKillop AM, Mooney MH, Harriott P, Flatt PR, O'Harte FP. McKillop AM, et al. Among authors: mooney mh. Biochem Biophys Res Commun. 2001 Aug 24;286(3):524-8. doi: 10.1006/bbrc.2001.5447. Biochem Biophys Res Commun. 2001. PMID: 11511090

9

Detection of glycated gastric inhibitory polypeptide within the intestines of diabetic obese (ob/ob) mice.

Mooney MH, Abdel-Wahab YH, Morgan LM, O'Harte FP, Flatt PR. Mooney MH, et al. Endocrine. 2001 Dec;16(3):167-71. doi: 10.1385/ENDO:16:3:167. Endocrine. 2001. PMID: 11954659

10

Improved biological activity of Gly2- and Ser2-substituted analogues of glucose-dependent insulinotrophic polypeptide.

Gault VA, Flatt PR, Harriott P, Mooney MH, Bailey CJ, O'Harte FP. Gault VA, et al. Among authors: mooney mh. J Endocrinol. 2003 Jan;176(1):133-41. doi: 10.1677/joe.0.1760133. J Endocrinol. 2003. PMID: 12525257

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