Moore CE - Search Results

1

cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity.

Xie J, Ponuwei GA, Moore CE, Willars GB, Tee AR, Herbert TP. Xie J, et al. Among authors: moore ce. Cell Signal. 2011 Dec;23(12):1927-35. doi: 10.1016/j.cellsig.2011.06.025. Epub 2011 Jul 6. Cell Signal. 2011. PMID: 21763421 Free PMC article.

2

Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2).

Barlow AD, Xie J, Moore CE, Campbell SC, Shaw JA, Nicholson ML, Herbert TP. Barlow AD, et al. Among authors: moore ce. Diabetologia. 2012 May;55(5):1355-65. doi: 10.1007/s00125-012-2475-7. Diabetologia. 2012. PMID: 22314813 Free PMC article.

3

Identification of cAMP-dependent kinase as a third in vivo ribosomal protein S6 kinase in pancreatic beta-cells.

Moore CE, Xie J, Gomez E, Herbert TP. Moore CE, et al. J Mol Biol. 2009 Jun 12;389(3):480-94. doi: 10.1016/j.jmb.2009.04.020. Epub 2009 Apr 16. J Mol Biol. 2009. PMID: 19376132

4

The selective recruitment of mRNA to the ER and an increase in initiation are important for glucose-stimulated proinsulin synthesis in pancreatic beta-cells.

Greenman IC, Gomez E, Moore CE, Herbert TP. Greenman IC, et al. Among authors: moore ce. Biochem J. 2005 Oct 15;391(Pt 2):291-300. doi: 10.1042/BJ20050468. Biochem J. 2005. PMID: 15972000 Free PMC article.

5

Distinct glucose-dependent stress responses revealed by translational profiling in pancreatic beta-cells.

Greenman IC, Gomez E, Moore CE, Herbert TP. Greenman IC, et al. Among authors: moore ce. J Endocrinol. 2007 Jan;192(1):179-87. doi: 10.1677/joe.1.06898. J Endocrinol. 2007. PMID: 17210755 Free PMC article.

6

Elongation factor 2 kinase promotes cell survival by inhibiting protein synthesis without inducing autophagy.

Moore CE, Wang X, Xie J, Pickford J, Barron J, Regufe da Mota S, Versele M, Proud CG. Moore CE, et al. Cell Signal. 2016 Apr;28(4):284-93. doi: 10.1016/j.cellsig.2016.01.005. Epub 2016 Jan 18. Cell Signal. 2016. PMID: 26795954 Free PMC article.

7

Exendin-4 stimulates islet cell replication via the IGF1 receptor activation of mTORC1/S6K1.

Xie J, El Sayed NM, Qi C, Zhao X, Moore CE, Herbert TP. Xie J, et al. Among authors: moore ce. J Mol Endocrinol. 2014 Aug;53(1):105-15. doi: 10.1530/JME-13-0200. J Mol Endocrinol. 2014. PMID: 24994913

8

Molecular mechanisms of muscarinic acetylcholine receptor-stimulated increase in cytosolic free Ca(2+) concentration and ERK1/2 activation in the MIN6 pancreatic β-cell line.

Selway JL, Moore CE, Mistry R, John Challiss RA, Herbert TP. Selway JL, et al. Among authors: moore ce. Acta Diabetol. 2012 Aug;49(4):277-89. doi: 10.1007/s00592-011-0314-9. Epub 2011 Aug 11. Acta Diabetol. 2012. PMID: 21833779 Free PMC article.

9

PERK activation at low glucose concentration is mediated by SERCA pump inhibition and confers preemptive cytoprotection to pancreatic β-cells.

Moore CE, Omikorede O, Gomez E, Willars GB, Herbert TP. Moore CE, et al. Mol Endocrinol. 2011 Feb;25(2):315-26. doi: 10.1210/me.2010-0309. Epub 2010 Dec 30. Mol Endocrinol. 2011. PMID: 21193559 Free PMC article.

10

Eukaryotic elongation factor 2 kinase activity is controlled by multiple inputs from oncogenic signaling.

Wang X, Regufe da Mota S, Liu R, Moore CE, Xie J, Lanucara F, Agarwala U, Pyr Dit Ruys S, Vertommen D, Rider MH, Eyers CE, Proud CG. Wang X, et al. Among authors: moore ce. Mol Cell Biol. 2014 Nov 15;34(22):4088-103. doi: 10.1128/MCB.01035-14. Epub 2014 Sep 2. Mol Cell Biol. 2014. PMID: 25182533 Free PMC article.

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