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The hypocretin/orexin system as a target for excessive motivation in alcohol use disorders.
Moorman DE. Moorman DE. Psychopharmacology (Berl). 2018 Jun;235(6):1663-1680. doi: 10.1007/s00213-018-4871-2. Epub 2018 Mar 6. Psychopharmacology (Berl). 2018. PMID: 29508004 Free PMC article. Review.
Science and government. An international framework to promote access to data.
Arzberger P, Schroeder P, Beaulieu A, Bowker G, Casey K, Laaksonen L, Moorman D, Uhlir P, Wouters P. Arzberger P, et al. Among authors: moorman d. Science. 2004 Mar 19;303(5665):1777-8. doi: 10.1126/science.1095958. Science. 2004. PMID: 15031482 No abstract available.
Assessment of a proposed "three-criteria" cocaine addiction model for use in reinstatement studies with rats.
Waters RP, Moorman DE, Young AB, Feltenstein MW, See RE. Waters RP, et al. Among authors: moorman de. Psychopharmacology (Berl). 2014 Aug;231(16):3197-205. doi: 10.1007/s00213-014-3497-2. Epub 2014 Mar 11. Psychopharmacology (Berl). 2014. PMID: 24615055
Motivational activation: a unifying hypothesis of orexin/hypocretin function.
Mahler SV, Moorman DE, Smith RJ, James MH, Aston-Jones G. Mahler SV, et al. Among authors: moorman de. Nat Neurosci. 2014 Oct;17(10):1298-303. doi: 10.1038/nn.3810. Epub 2014 Sep 25. Nat Neurosci. 2014. PMID: 25254979 Free PMC article. Review.
Differential roles of medial prefrontal subregions in the regulation of drug seeking.
Moorman DE, James MH, McGlinchey EM, Aston-Jones G. Moorman DE, et al. Brain Res. 2015 Dec 2;1628(Pt A):130-46. doi: 10.1016/j.brainres.2014.12.024. Epub 2014 Dec 18. Brain Res. 2015. PMID: 25529632 Free PMC article. Review.
Orexin/hypocretin neuron activation is correlated with alcohol seeking and preference in a topographically specific manner.
Moorman DE, James MH, Kilroy EA, Aston-Jones G. Moorman DE, et al. Eur J Neurosci. 2016 Mar;43(5):710-20. doi: 10.1111/ejn.13170. Epub 2016 Feb 16. Eur J Neurosci. 2016. PMID: 26750264 Free PMC article.
The highly selective orexin/hypocretin 1 receptor antagonist GSK1059865 potently reduces ethanol drinking in ethanol dependent mice.
Lopez MF, Moorman DE, Aston-Jones G, Becker HC. Lopez MF, et al. Among authors: moorman de. Brain Res. 2016 Apr 1;1636:74-80. doi: 10.1016/j.brainres.2016.01.049. Epub 2016 Feb 4. Brain Res. 2016. PMID: 26851547 Free PMC article.
Orexin/hypocretin-1 receptor antagonism reduces ethanol self-administration and reinstatement selectively in highly-motivated rats.
Moorman DE, James MH, Kilroy EA, Aston-Jones G. Moorman DE, et al. Brain Res. 2017 Jan 1;1654(Pt A):34-42. doi: 10.1016/j.brainres.2016.10.018. Epub 2016 Oct 19. Brain Res. 2017. PMID: 27771284 Free PMC article.
A Decade of Orexin/Hypocretin and Addiction: Where Are We Now?
James MH, Mahler SV, Moorman DE, Aston-Jones G. James MH, et al. Among authors: moorman de. Curr Top Behav Neurosci. 2017;33:247-281. doi: 10.1007/7854_2016_57. Curr Top Behav Neurosci. 2017. PMID: 28012090 Free PMC article. Review.
The role of the orbitofrontal cortex in alcohol use, abuse, and dependence.
Moorman DE. Moorman DE. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Dec 20;87(Pt A):85-107. doi: 10.1016/j.pnpbp.2018.01.010. Epub 2018 Feb 9. Prog Neuropsychopharmacol Biol Psychiatry. 2018. PMID: 29355587 Free PMC article. Review.
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