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IL-17 for therapy.
Kurschus FC, Moos S. Kurschus FC, et al. J Dermatol Sci. 2017 Sep;87(3):221-227. doi: 10.1016/j.jdermsci.2017.06.010. Epub 2017 Jun 15. J Dermatol Sci. 2017. PMID: 28633806 Review.
Regulation of IL-22BP in psoriasis.
Voglis S, Moos S, Kloos L, Wanke F, Zayoud M, Pelczar P, Giannou AD, Pezer S, Albers M, Luessi F, Huber S, Schäkel K, Kurschus FC. Voglis S, et al. Among authors: moos s. Sci Rep. 2018 Mar 23;8(1):5085. doi: 10.1038/s41598-018-23510-3. Sci Rep. 2018. PMID: 29572462 Free PMC article.
Expression of IL-17F is associated with non-pathogenic Th17 cells.
Wanke F, Tang Y, Gronke K, Klebow S, Moos S, Hauptmann J, Shanmugavadivu A, Regen T, Mufazalov IA, Gabriel LA, Reißig S, Diefenbach A, Kurschus FC, Waisman A. Wanke F, et al. Among authors: moos s. J Mol Med (Berl). 2018 Aug;96(8):819-829. doi: 10.1007/s00109-018-1662-5. Epub 2018 Jun 29. J Mol Med (Berl). 2018. PMID: 29959474
Imiquimod-Induced Psoriasis in Mice Depends on the IL-17 Signaling of Keratinocytes.
Moos S, Mohebiany AN, Waisman A, Kurschus FC. Moos S, et al. J Invest Dermatol. 2019 May;139(5):1110-1117. doi: 10.1016/j.jid.2019.01.006. Epub 2019 Jan 23. J Invest Dermatol. 2019. PMID: 30684554
Lugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors.
Bitschar K, Sauer B, Focken J, Dehmer H, Moos S, Konnerth M, Schilling NA, Grond S, Kalbacher H, Kurschus FC, Götz F, Krismer B, Peschel A, Schittek B. Bitschar K, et al. Among authors: moos s. Nat Commun. 2019 Jun 21;10(1):2730. doi: 10.1038/s41467-019-10646-7. Nat Commun. 2019. PMID: 31227691 Free PMC article.
IL-17+ CD8+ T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis.
Lückel C, Picard F, Raifer H, Campos Carrascosa L, Guralnik A, Zhang Y, Klein M, Bittner S, Steffen F, Moos S, Marini F, Gloury R, Kurschus FC, Chao YY, Bertrams W, Sexl V, Schmeck B, Bonetti L, Grusdat M, Lohoff M, Zielinski CE, Zipp F, Kallies A, Brenner D, Berger M, Bopp T, Tackenberg B, Huber M. Lückel C, et al. Among authors: moos s. Nat Commun. 2019 Dec 16;10(1):5722. doi: 10.1038/s41467-019-13731-z. Nat Commun. 2019. PMID: 31844089 Free PMC article. Clinical Trial.
Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood-brain barrier.
Hauptmann J, Johann L, Marini F, Kitic M, Colombo E, Mufazalov IA, Krueger M, Karram K, Moos S, Wanke F, Kurschus FC, Klein M, Cardoso S, Strauß J, Bolisetty S, Lühder F, Schwaninger M, Binder H, Bechman I, Bopp T, Agarwal A, Soares MP, Regen T, Waisman A. Hauptmann J, et al. Among authors: moos s. Acta Neuropathol. 2020 Jul 11. doi: 10.1007/s00401-020-02187-x. Online ahead of print. Acta Neuropathol. 2020. PMID: 32651669
EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells.
Wanke F, Moos S, Croxford AL, Heinen AP, Gräf S, Kalt B, Tischner D, Zhang J, Christen I, Bruttger J, Yogev N, Tang Y, Zayoud M, Israel N, Karram K, Reißig S, Lacher SM, Reichhold C, Mufazalov IA, Ben-Nun A, Kuhlmann T, Wettschureck N, Sailer AW, Rajewsky K, Casola S, Waisman A, Kurschus FC. Wanke F, et al. Cell Rep. 2017 Jan 31;18(5):1270-1284. doi: 10.1016/j.celrep.2017.01.020. Cell Rep. 2017. PMID: 28147280
The actin remodeling protein cofilin is crucial for thymic αβ but not γδ T-cell development.
Seeland I, Xiong Y, Orlik C, Deibel D, Prokosch S, Küblbeck G, Jahraus B, De Stefano D, Moos S, Kurschus FC, Arnold B, Samstag Y. Seeland I, et al. Among authors: moos s. PLoS Biol. 2018 Jul 9;16(7):e2005380. doi: 10.1371/journal.pbio.2005380. eCollection 2018 Jul. PLoS Biol. 2018. PMID: 29985916 Free PMC article.
Dimethyl fumarate alters intracellular Ca2+ handling in immune cells by redox-mediated pleiotropic effects.
Herrmann AK, Wüllner V, Moos S, Graf J, Chen J, Kieseier B, Kurschus FC, Albrecht P, Vangheluwe P, Methner A. Herrmann AK, et al. Among authors: moos s. Free Radic Biol Med. 2019 Sep;141:338-347. doi: 10.1016/j.freeradbiomed.2019.07.005. Epub 2019 Jul 4. Free Radic Biol Med. 2019. PMID: 31279969
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