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Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha.
Bourguet W, Ruff M, Chambon P, Gronemeyer H, Moras D. Bourguet W, et al. Among authors: moras d. Nature. 1995 Jun 1;375(6530):377-82. doi: 10.1038/375377a0. Nature. 1995. PMID: 7760929
Crystallization of aspartyl-tRNA synthetase-tRNA(Asp) complex from Escherichia coli and first crystallographic results.
Eiler S, Boeglin M, Martin F, Eriani G, Gangloff J, Thierry JC, Moras D. Eiler S, et al. Among authors: moras d. J Mol Biol. 1992 Apr 20;224(4):1171-3. doi: 10.1016/0022-2836(92)90478-3. J Mol Biol. 1992. PMID: 1569573
Silicon analogues of the RXR-selective retinoid agonist SR11237 (BMS649): chemistry and biology.
Lippert WP, Burschka C, Götz K, Kaupp M, Ivanova D, Gaudon C, Sato Y, Antony P, Rochel N, Moras D, Gronemeyer H, Tacke R. Lippert WP, et al. Among authors: moras d. ChemMedChem. 2009 Jul;4(7):1143-52. doi: 10.1002/cmdc.200900090. ChemMedChem. 2009. PMID: 19496083
1α,25(OH)2-3-epi-vitamin D3, a natural physiological metabolite of vitamin D3: its synthesis, biological activity and crystal structure with its receptor.
Molnár F, Sigüeiro R, Sato Y, Araujo C, Schuster I, Antony P, Peluso J, Muller C, Mouriño A, Moras D, Rochel N. Molnár F, et al. Among authors: moras d. PLoS One. 2011 Mar 31;6(3):e18124. doi: 10.1371/journal.pone.0018124. PLoS One. 2011. PMID: 21483824 Free PMC article.
Ligand binding domain of vitamin D receptors.
Rochel N, Moras D. Rochel N, et al. Among authors: moras d. Curr Top Med Chem. 2006;6(12):1229-41. doi: 10.2174/156802606777864926. Curr Top Med Chem. 2006. PMID: 16848737 Review.
Structural basis for the accommodation of bis- and tris-aromatic derivatives in vitamin D nuclear receptor.
Ciesielski F, Sato Y, Chebaro Y, Moras D, Dejaegere A, Rochel N. Ciesielski F, et al. Among authors: moras d. J Med Chem. 2012 Oct 11;55(19):8440-9. doi: 10.1021/jm300858s. Epub 2012 Sep 19. J Med Chem. 2012. PMID: 22957834
Structure-function relationships and crystal structures of the vitamin D receptor bound 2 alpha-methyl-(20S,23S)- and 2 alpha-methyl-(20S,23R)-epoxymethano-1 alpha,25-dihydroxyvitamin D3.
Antony P, Sigüeiro R, Huet T, Sato Y, Ramalanjaona N, Rodrigues LC, Mouriño A, Moras D, Rochel N. Antony P, et al. Among authors: moras d. J Med Chem. 2010 Feb 11;53(3):1159-71. doi: 10.1021/jm9014636. J Med Chem. 2010. PMID: 20070104
Structure-based design of a superagonist ligand for the vitamin D nuclear receptor.
Hourai S, Rodrigues LC, Antony P, Reina-San-Martin B, Ciesielski F, Magnier BC, Schoonjans K, Mouriño A, Rochel N, Moras D. Hourai S, et al. Among authors: moras d. Chem Biol. 2008 Apr;15(4):383-92. doi: 10.1016/j.chembiol.2008.03.016. Chem Biol. 2008. PMID: 18420145
Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification.
Tocchini-Valentini G, Rochel N, Wurtz JM, Moras D. Tocchini-Valentini G, et al. Among authors: moras d. J Med Chem. 2004 Apr 8;47(8):1956-61. doi: 10.1021/jm0310582. J Med Chem. 2004. PMID: 15055995
Structural analysis of nuclear receptors: from isolated domains to integral proteins.
Brélivet Y, Rochel N, Moras D. Brélivet Y, et al. Among authors: moras d. Mol Cell Endocrinol. 2012 Jan 30;348(2):466-73. doi: 10.1016/j.mce.2011.08.015. Epub 2011 Aug 25. Mol Cell Endocrinol. 2012. PMID: 21888944 Review.
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