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Current status and potential application of ISCOMs in veterinary medicine.
Morein B, Hu KF, Abusugra I. Morein B, et al. Adv Drug Deliv Rev. 2004 Jun 23;56(10):1367-82. doi: 10.1016/j.addr.2004.02.004. Adv Drug Deliv Rev. 2004. PMID: 15191787 Review.
Subsequently, the T cell response is localised to the spleen, while the B cell response is first found both in the draining lymph nodes and in the spleen. ...In contrast, antigens that have been adjuvanted in an oil emulsion, limit the T cell response to the draining lymph …
Subsequently, the T cell response is localised to the spleen, while the B cell response is first found both in the draining lymph nod …
Plasmodium falciparum: the immune response in rabbits to the clustered asparagine-rich protein (CARP) after immunization in Freund's adjuvant or immunostimulating complexes (ISCOMs).
Sjölander A, Ståhl S, Lövgren K, Hansson M, Cavelier L, Walles A, Helmby H, Wåhlin B, Morein B, Uhlén M, et al. Sjölander A, et al. Exp Parasitol. 1993 Mar;76(2):134-45. doi: 10.1006/expr.1993.1016. Exp Parasitol. 1993. PMID: 8454022
Long-standing protection of macaques against cell-free HIV-2 with a HIV-2 iscom vaccine.
Putkonen P, Björling E, Akerblom L, Thorstensson R, Lövgren K, Benthin L, Chiodi F, Morein B, Biberfeld G, Norrby E, et al. Putkonen P, et al. J Acquir Immune Defic Syndr (1988). 1994 Jun;7(6):551-9. J Acquir Immune Defic Syndr (1988). 1994. PMID: 8176640
Immunomodulation by iscoms, immune stimulating complexes.
Morein B, Bengtsson KL. Morein B, et al. Methods. 1999 Sep;19(1):94-102. doi: 10.1006/meth.1999.0833. Methods. 1999. PMID: 10525444 Review.
Iscoms prominently enhance the antigen targeting, uptake, and activity of antigen presenting cells including dendritic and B cells and macrophages resulting in the production of proinflammatory cytokines, above all interleukin (IL)-1, IL-6, and IL-12. ...
Iscoms prominently enhance the antigen targeting, uptake, and activity of antigen presenting cells including dendritic and B cells an …
Kinetics, localization and characteristics of B- and T-cell responses to iscoms containing human influenza virus glycoproteins.
Johansson M, Lövgren-Bengtsson K, Sjölander A, Morein B. Johansson M, et al. Dev Biol Stand. 1998;92:289-94. Dev Biol Stand. 1998. PMID: 9554283
B- and T-cell responses have been studied after primary and secondary immunizations of mice with iscoms containing influenza virus envelope glycoproteins. After primary immunization both B- and T-cell responses were initiated in the draining lymph nodes. T-cells sho
B- and T-cell responses have been studied after primary and secondary immunizations of mice with iscoms containing influenza virus en
The induction of cell-associated and secreted IL-1 by iscoms, matrix or micelles in murine splenic cells.
Villacres-Eriksson M, Bergström-Mollaoglu M, Kåberg H, Lövgren K, Morein B. Villacres-Eriksson M, et al. Clin Exp Immunol. 1993 Jul;93(1):120-5. doi: 10.1111/j.1365-2249.1993.tb06507.x. Clin Exp Immunol. 1993. PMID: 8324897 Free PMC article.
Antigen-specific increases in the number of splenocytes expressing MHC class II molecules following restimulation with antigen in various physical forms.
Bergström-Mollaoglu M, Lövgren K, Akerblom L, Fossum C, Morein B. Bergström-Mollaoglu M, et al. Scand J Immunol. 1992 Oct;36(4):565-74. doi: 10.1111/j.1365-3083.1992.tb03225.x. Scand J Immunol. 1992. PMID: 1411302
Effect of oral rotavirus/iscom vaccines on immune responses in gnotobiotic lambs.
van Pinxteren LA, Bruce MG, Campbell I, Wood A, Clarke CJ, Bellman A, Morein B, Snodgrass DR. van Pinxteren LA, et al. Vet Immunol Immunopathol. 1999 Oct 1;71(1):53-67. doi: 10.1016/s0165-2427(99)00087-2. Vet Immunol Immunopathol. 1999. PMID: 10522786
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