Moreth K - Search Results

1

The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis.

Moreth K, Brodbeck R, Babelova A, Gretz N, Spieker T, Zeng-Brouwers J, Pfeilschifter J, Young MF, Schaefer RM, Schaefer L. Moreth K, et al. J Clin Invest. 2010 Dec;120(12):4251-72. doi: 10.1172/JCI42213. Epub 2010 Nov 15. J Clin Invest. 2010. PMID: 21084753 Free PMC article.

2

Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.

Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Gröne HJ, Schaefer L. Babelova A, et al. Among authors: moreth k. J Biol Chem. 2009 Sep 4;284(36):24035-48. doi: 10.1074/jbc.M109.014266. Epub 2009 Jul 15. J Biol Chem. 2009. PMID: 19605353 Free PMC article.

3

Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury.

Moreth K, Frey H, Hubo M, Zeng-Brouwers J, Nastase MV, Hsieh LT, Haceni R, Pfeilschifter J, Iozzo RV, Schaefer L. Moreth K, et al. Matrix Biol. 2014 Apr;35:143-51. doi: 10.1016/j.matbio.2014.01.010. Epub 2014 Jan 28. Matrix Biol. 2014. PMID: 24480070 Free PMC article.

4

Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21.

Merline R, Moreth K, Beckmann J, Nastase MV, Zeng-Brouwers J, Tralhão JG, Lemarchand P, Pfeilschifter J, Schaefer RM, Iozzo RV, Schaefer L. Merline R, et al. Among authors: moreth k. Sci Signal. 2011 Nov 15;4(199):ra75. doi: 10.1126/scisignal.2001868. Sci Signal. 2011. PMID: 22087031 Free PMC article.

5

A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia.

Frey H, Moreth K, Hsieh LT, Zeng-Brouwers J, Rathkolb B, Fuchs H, Gailus-Durner V, Iozzo RV, de Angelis MH, Schaefer L. Frey H, et al. Among authors: moreth k. Glycoconj J. 2017 Jun;34(3):393-404. doi: 10.1007/s10719-016-9722-y. Epub 2016 Sep 6. Glycoconj J. 2017. PMID: 27600268

6

Biglycan is a new high-affinity ligand for CD14 in macrophages.

Roedig H, Nastase MV, Frey H, Moreth K, Zeng-Brouwers J, Poluzzi C, Hsieh LT, Brandts C, Fulda S, Wygrecka M, Schaefer L. Roedig H, et al. Among authors: moreth k. Matrix Biol. 2019 Apr;77:4-22. doi: 10.1016/j.matbio.2018.05.006. Epub 2018 May 17. Matrix Biol. 2019. PMID: 29777767

7

Molecular mechanisms of TGF beta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506.

Akool el-S, Doller A, Babelova A, Tsalastra W, Moreth K, Schaefer L, Pfeilschifter J, Eberhardt W. Akool el-S, et al. Among authors: moreth k. J Immunol. 2008 Aug 15;181(4):2831-45. doi: 10.4049/jimmunol.181.4.2831. J Immunol. 2008. PMID: 18684975

8

Small leucine-rich proteoglycans orchestrate receptor crosstalk during inflammation.

Moreth K, Iozzo RV, Schaefer L. Moreth K, et al. Cell Cycle. 2012 Jun 1;11(11):2084-91. doi: 10.4161/cc.20316. Epub 2012 Jun 1. Cell Cycle. 2012. PMID: 22580469 Free PMC article. Review.

9

Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression.

Ren S, Babelova A, Moreth K, Xin C, Eberhardt W, Doller A, Pavenstädt H, Schaefer L, Pfeilschifter J, Huwiler A. Ren S, et al. Among authors: moreth k. Kidney Int. 2009 Oct;76(8):857-67. doi: 10.1038/ki.2009.297. Epub 2009 Aug 5. Kidney Int. 2009. PMID: 19657322 Free article.

10

Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4.

Allam R, Scherbaum CR, Darisipudi MN, Mulay SR, Hägele H, Lichtnekert J, Hagemann JH, Rupanagudi KV, Ryu M, Schwarzenberger C, Hohenstein B, Hugo C, Uhl B, Reichel CA, Krombach F, Monestier M, Liapis H, Moreth K, Schaefer L, Anders HJ. Allam R, et al. Among authors: moreth k. J Am Soc Nephrol. 2012 Aug;23(8):1375-88. doi: 10.1681/ASN.2011111077. Epub 2012 Jun 7. J Am Soc Nephrol. 2012. PMID: 22677551 Free PMC article.

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