Morgan RA - Search Results

1

Adoptive cell transfer: a clinical path to effective cancer immunotherapy.

Rosenberg SA, Restifo NP, Yang JC, Morgan RA, Dudley ME. Rosenberg SA, et al. Among authors: morgan ra. Nat Rev Cancer. 2008 Apr;8(4):299-308. doi: 10.1038/nrc2355. Nat Rev Cancer. 2008. PMID: 18354418 Free PMC article. Review.

2

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen.

Johnson LA, Morgan RA, Dudley ME, Cassard L, Yang JC, Hughes MS, Kammula US, Royal RE, Sherry RM, Wunderlich JR, Lee CC, Restifo NP, Schwarz SL, Cogdill AP, Bishop RJ, Kim H, Brewer CC, Rudy SF, VanWaes C, Davis JL, Mathur A, Ripley RT, Nathan DA, Laurencot CM, Rosenberg SA. Johnson LA, et al. Among authors: morgan ra. Blood. 2009 Jul 16;114(3):535-46. doi: 10.1182/blood-2009-03-211714. Epub 2009 May 18. Blood. 2009. PMID: 19451549 Free PMC article. Clinical Trial.

3

Lack of specific gamma-retroviral vector long terminal repeat promoter silencing in patients receiving genetically engineered lymphocytes and activation upon lymphocyte restimulation.

Burns WR, Zheng Z, Rosenberg SA, Morgan RA. Burns WR, et al. Among authors: morgan ra. Blood. 2009 Oct 1;114(14):2888-99. doi: 10.1182/blood-2009-01-199216. Epub 2009 Jul 9. Blood. 2009. PMID: 19589923 Free PMC article.

4

Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2.

Morgan RA, Yang JC, Kitano M, Dudley ME, Laurencot CM, Rosenberg SA. Morgan RA, et al. Mol Ther. 2010 Apr;18(4):843-51. doi: 10.1038/mt.2010.24. Epub 2010 Feb 23. Mol Ther. 2010. PMID: 20179677 Free PMC article.

5

A high molecular weight melanoma-associated antigen-specific chimeric antigen receptor redirects lymphocytes to target human melanomas.

Burns WR, Zhao Y, Frankel TL, Hinrichs CS, Zheng Z, Xu H, Feldman SA, Ferrone S, Rosenberg SA, Morgan RA. Burns WR, et al. Among authors: morgan ra. Cancer Res. 2010 Apr 15;70(8):3027-33. doi: 10.1158/0008-5472.CAN-09-2824. Cancer Res. 2010. PMID: 20395199 Free PMC article.

6

Both CD4 and CD8 T cells mediate equally effective in vivo tumor treatment when engineered with a highly avid TCR targeting tyrosinase.

Frankel TL, Burns WR, Peng PD, Yu Z, Chinnasamy D, Wargo JA, Zheng Z, Restifo NP, Rosenberg SA, Morgan RA. Frankel TL, et al. Among authors: morgan ra. J Immunol. 2010 Jun 1;184(11):5988-98. doi: 10.4049/jimmunol.1000189. Epub 2010 Apr 28. J Immunol. 2010. PMID: 20427771 Free PMC article.

7

A simplified method for the clinical-scale generation of central memory-like CD8+ T cells after transduction with lentiviral vectors encoding antitumor antigen T-cell receptors.

Yang S, Dudley ME, Rosenberg SA, Morgan RA. Yang S, et al. Among authors: morgan ra. J Immunother. 2010 Jul-Aug;33(6):648-58. doi: 10.1097/CJI.0b013e3181e311cb. J Immunother. 2010. PMID: 20551831 Free PMC article.

8

Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts.

Kerkar SP, Muranski P, Kaiser A, Boni A, Sanchez-Perez L, Yu Z, Palmer DC, Reger RN, Borman ZA, Zhang L, Morgan RA, Gattinoni L, Rosenberg SA, Trinchieri G, Restifo NP. Kerkar SP, et al. Among authors: morgan ra. Cancer Res. 2010 Sep 1;70(17):6725-34. doi: 10.1158/0008-5472.CAN-10-0735. Epub 2010 Jul 20. Cancer Res. 2010. PMID: 20647327 Free PMC article.

9

Adoptive cell therapy: genetic modification to redirect effector cell specificity.

Morgan RA, Dudley ME, Rosenberg SA. Morgan RA, et al. Cancer J. 2010 Jul-Aug;16(4):336-41. doi: 10.1097/PPO.0b013e3181eb3879. Cancer J. 2010. PMID: 20693844 Free PMC article. Review.

10

Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy.

Hinrichs CS, Borman ZA, Gattinoni L, Yu Z, Burns WR, Huang J, Klebanoff CA, Johnson LA, Kerkar SP, Yang S, Muranski P, Palmer DC, Scott CD, Morgan RA, Robbins PF, Rosenberg SA, Restifo NP. Hinrichs CS, et al. Among authors: morgan ra. Blood. 2011 Jan 20;117(3):808-14. doi: 10.1182/blood-2010-05-286286. Epub 2010 Oct 22. Blood. 2011. PMID: 20971955 Free PMC article.

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