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Spectroscopic study of the interaction of U(VI) with transferrin and albumin for speciation of U(VI) under blood serum conditions.
Montavon G, Apostolidis C, Bruchertseifer F, Repinc U, Morgenstern A. Montavon G, et al. J Inorg Biochem. 2009 Dec;103(12):1609-16. doi: 10.1016/j.jinorgbio.2009.08.010. Epub 2009 Sep 2. J Inorg Biochem. 2009. PMID: 19800129
The quantitative description of the interactions of uranium with blood serum components is of high relevance for a rational design of molecules suitable for in vivo chelation of uranium. ...In addition, the results show that Ca(II) must be considered in the model as a
The quantitative description of the interactions of uranium with blood serum components is of high relevance for a rational design of …
Cross-sections of the reaction 232Th(p,3n)230Pa for production of 230U for targeted alpha therapy.
Morgenstern A, Apostolidis C, Bruchertseifer F, Capote R, Gouder T, Simonelli F, Sin M, Abbas K. Morgenstern A, et al. Appl Radiat Isot. 2008 Oct;66(10):1275-80. doi: 10.1016/j.apradiso.2008.02.066. Epub 2008 Feb 20. Appl Radiat Isot. 2008. PMID: 18374585
(230)U/(226)Th is a promising novel alpha-emitter system for application in targeted alpha therapy of cancer. The therapeutic nuclides can be produced by proton irradiation of natural (232)Th according to the reaction (232)Th(p,3n)(230)Pa, followed by subsequent beta decay …
(230)U/(226)Th is a promising novel alpha-emitter system for application in targeted alpha therapy of cancer. The therapeutic nuclide …
Production of 230U/226Th for targeted alpha therapy via proton irradiation of 231Pa.
Morgenstern A, Lebeda O, Stursa J, Bruchertseifer F, Capote R, McGinley J, Rasmussen G, Sin M, Zielinska B, Apostolidis C. Morgenstern A, et al. Anal Chem. 2008 Nov 15;80(22):8763-70. doi: 10.1021/ac801304c. Epub 2008 Oct 17. Anal Chem. 2008. PMID: 18925748
Beam parameters (energy and intensity) were determined both by calculation using a mathematical model based on measured beam orbits and beam current integrator and by parallel monitor reactions on copper foils using high-resolution gamma-spectrometry and IAEA recommended c …
Beam parameters (energy and intensity) were determined both by calculation using a mathematical model based on measured beam orbits a …
Investigation of para-sulfonatocalix[n]arenes [n = 6, 8] as potential chelates for (230)U.
Montavon G, Repinc U, Apostolidis C, Bruchertseifer F, Abbas K, Morgenstern A. Montavon G, et al. Dalton Trans. 2010 Feb 7;39(5):1366-74. doi: 10.1039/b918426k. Epub 2009 Dec 2. Dalton Trans. 2010. PMID: 20104364
Is DTPA a good competing chelating agent for Th(IV) in human serum and suitable in targeted alpha therapy?
Le Du A, Sabatié-Gogova A, Morgenstern A, Montavon G. Le Du A, et al. J Inorg Biochem. 2012 Apr;109:82-9. doi: 10.1016/j.jinorgbio.2011.12.011. Epub 2011 Dec 30. J Inorg Biochem. 2012. PMID: 22388013
Human serum transferrin (HSTF) interacts strongly with Th(IV), forming a ternary complex including two synergistic carbonate anions. ...This makes DTPA a potential chelating agent for synthesis of (226)Th-labelled biomolecules for application in targeted alpha thera …
Human serum transferrin (HSTF) interacts strongly with Th(IV), forming a ternary complex including two synergistic carbonate anions. …
Preclinical Targeted α- and β--Radionuclide Therapy in HER2-Positive Brain Metastasis Using Camelid Single-Domain Antibodies.
Puttemans J, Dekempeneer Y, Eersels JL, Hanssens H, Debie P, Keyaerts M, Windhorst AD, van der Aa F, Lecocq Q, Breckpot K, Morgenstern A, Bruchertseifer F, Lahoutte T, Devoogdt N, D'Huyvetter M. Puttemans J, et al. Among authors: morgenstern a. Cancers (Basel). 2020 Apr 21;12(4):1017. doi: 10.3390/cancers12041017. Cancers (Basel). 2020. PMID: 32326199 Free PMC article.
First patient exceeding 5-year complete remission after 225Ac-PSMA-TAT.
Rathke H, Bruchertseifer F, Kratochwil C, Keller H, Giesel FL, Apostolidis C, Haberkorn U, Morgenstern A. Rathke H, et al. Among authors: morgenstern a. Eur J Nucl Med Mol Imaging. 2020 May 28. doi: 10.1007/s00259-020-04875-y. Online ahead of print. Eur J Nucl Med Mol Imaging. 2020. PMID: 32468252 No abstract available.
First-Generation Bispidine Chelators for 213 BiIII Radiopharmaceutical Applications.
Bruchertseifer F, Comba P, Martin B, Morgenstern A, Notni J, Starke M, Wadepohl H. Bruchertseifer F, et al. Among authors: morgenstern a. ChemMedChem. 2020 Jul 2. doi: 10.1002/cmdc.202000361. Online ahead of print. ChemMedChem. 2020. PMID: 32613737
Age determination of highly enriched uranium: separation and analysis of 231Pa.
Morgenstern A, Apostolidis C, Mayer K. Morgenstern A, et al. Anal Chem. 2002 Nov 1;74(21):5513-6. doi: 10.1021/ac0203948. Anal Chem. 2002. PMID: 12433081
It affords decontamination factors exceeding 2.5 x 10(7), overall recoveries in the range of 80-85%, and a combined uncertainty below 5%....
It affords decontamination factors exceeding 2.5 x 10(7), overall recoveries in the range of 80-85%, and a combined uncertainty below …
High-resolution alpha-particle spectrometry of the 230U decay series.
Marouli M, Pommé S, Paepen J, Van Ammel R, Jobbágy V, Dirican A, Suliman G, Stroh H, Apostolidis C, Abbas K, Morgenstern A. Marouli M, et al. Appl Radiat Isot. 2012 Sep;70(9):2270-4. doi: 10.1016/j.apradiso.2012.02.107. Epub 2012 Mar 6. Appl Radiat Isot. 2012. PMID: 22424835
A (230)U source was prepared on a stainless steel disc by electrodeposition in an ammonium nitrate solution. Spectrometry of the alpha-particle energy spectrum was performed with ion-implanted planar silicon detectors in vacuum. ...A good agreement with liter
A (230)U source was prepared on a stainless steel disc by electrodeposition in an ammonium nitrate solution. Spectrometry of t
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