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Page 1
Identification of a Proteasome-Targeting Arylsulfonamide with Potential for the Treatment of Chagas' Disease.
Lima ML, Tulloch LB, Corpas-Lopez V, Carvalho S, Wall RJ, Milne R, Rico E, Patterson S, Gilbert IH, Moniz S, MacLean L, Torrie LS, Morgillo C, Horn D, Zuccotto F, Wyllie S. Lima ML, et al. Among authors: morgillo c. Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0153521. doi: 10.1128/AAC.01535-21. Epub 2021 Oct 4. Antimicrob Agents Chemother. 2022. PMID: 34606338 Free PMC article.
Design, synthesis and in vitro and in vivo biological evaluation of flurbiprofen amides as new fatty acid amide hydrolase/cyclooxygenase-2 dual inhibitory potential analgesic agents.
Deplano A, Karlsson J, Moraca F, Svensson M, Cristiano C, Morgillo CM, Fowler CJ, Russo R, Catalanotti B, Onnis V. Deplano A, et al. Among authors: morgillo cm. J Enzyme Inhib Med Chem. 2021 Dec;36(1):940-953. doi: 10.1080/14756366.2021.1875459. J Enzyme Inhib Med Chem. 2021. PMID: 33896320 Free PMC article.
Interaction of the N-(3-Methylpyridin-2-yl)amide Derivatives of Flurbiprofen and Ibuprofen with FAAH: Enantiomeric Selectivity and Binding Mode.
Karlsson J, Morgillo CM, Deplano A, Smaldone G, Pedone E, Luque FJ, Svensson M, Novellino E, Congiu C, Onnis V, Catalanotti B, Fowler CJ. Karlsson J, et al. Among authors: morgillo cm. PLoS One. 2015 Nov 13;10(11):e0142711. doi: 10.1371/journal.pone.0142711. eCollection 2015. PLoS One. 2015. PMID: 26565710 Free PMC article.
Novel propanamides as fatty acid amide hydrolase inhibitors.
Deplano A, Morgillo CM, Demurtas M, Björklund E, Cipriano M, Svensson M, Hashemian S, Smaldone G, Pedone E, Luque FJ, Cabiddu MG, Novellino E, Fowler CJ, Catalanotti B, Onnis V. Deplano A, et al. Among authors: morgillo cm. Eur J Med Chem. 2017 Aug 18;136:523-542. doi: 10.1016/j.ejmech.2017.05.033. Epub 2017 May 12. Eur J Med Chem. 2017. PMID: 28535469
Exploitation of a very small peptide nucleic acid as a new inhibitor of miR-509-3p involved in the regulation of cystic fibrosis disease-gene expression.
Amato F, Tomaiuolo R, Nici F, Borbone N, Elce A, Catalanotti B, D'Errico S, Morgillo CM, De Rosa G, Mayol L, Piccialli G, Oliviero G, Castaldo G. Amato F, et al. Among authors: morgillo cm. Biomed Res Int. 2014;2014:610718. doi: 10.1155/2014/610718. Epub 2014 Apr 15. Biomed Res Int. 2014. PMID: 24829907 Free PMC article.
Structural model of the hUbA1-UbcH10 quaternary complex: in silico and experimental analysis of the protein-protein interactions between E1, E2 and ubiquitin.
Correale S, de Paola I, Morgillo CM, Federico A, Zaccaro L, Pallante P, Galeone A, Fusco A, Pedone E, Luque FJ, Catalanotti B. Correale S, et al. Among authors: morgillo cm. PLoS One. 2014 Nov 6;9(11):e112082. doi: 10.1371/journal.pone.0112082. eCollection 2014. PLoS One. 2014. PMID: 25375166 Free PMC article.
Exploring the DNA2-PNA heterotriplex formation in targeting the Bcl-2 gene promoter: A structural insight by physico-chemical and microsecond-scale MD investigation.
Falanga AP, Lupia A, Tripodi L, Morgillo CM, Moraca F, Roviello GN, Catalanotti B, Amato J, Pastore L, Cerullo V, D'Errico S, Piccialli G, Oliviero G, Borbone N. Falanga AP, et al. Among authors: morgillo cm. Heliyon. 2024 Jan 22;10(3):e24599. doi: 10.1016/j.heliyon.2024.e24599. eCollection 2024 Feb 15. Heliyon. 2024. PMID: 38317891 Free PMC article.
Molecular Basis for Non-Covalent, Non-Competitive FAAH Inhibition.
Morgillo CM, Lupia A, Deplano A, Pirone L, Fiorillo B, Pedone E, Luque FJ, Onnis V, Moraca F, Catalanotti B. Morgillo CM, et al. Int J Mol Sci. 2022 Dec 7;23(24):15502. doi: 10.3390/ijms232415502. Int J Mol Sci. 2022. PMID: 36555144 Free PMC article.