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STAT5BN642H is a driver mutation for T cell neoplasia.
Pham HTT, Maurer B, Prchal-Murphy M, Grausenburger R, Grundschober E, Javaheri T, Nivarthi H, Boersma A, Kolbe T, Elabd M, Halbritter F, Pencik J, Kazemi Z, Grebien F, Hengstschläger M, Kenner L, Kubicek S, Farlik M, Bock C, Valent P, Müller M, Rülicke T, Sexl V, Moriggl R. Pham HTT, et al. Among authors: moriggl r. J Clin Invest. 2018 Jan 2;128(1):387-401. doi: 10.1172/JCI94509. Epub 2017 Dec 4. J Clin Invest. 2018. PMID: 29200404 Free PMC article.
Jak1 deficiency leads to enhanced Abelson-induced B-cell tumor formation.
Sexl V, Kovacic B, Piekorz R, Moriggl R, Stoiber D, Hoffmeyer A, Liebminger R, Kudlacek O, Weisz E, Rothammer K, Ihle JN. Sexl V, et al. Among authors: moriggl r. Blood. 2003 Jun 15;101(12):4937-43. doi: 10.1182/blood-2001-11-0142. Epub 2003 Feb 6. Blood. 2003. PMID: 12576323 Free article.
JunB inhibits proliferation and transformation in B-lymphoid cells.
Szremska AP, Kenner L, Weisz E, Ott RG, Passegué E, Artwohl M, Freissmuth M, Stoxreiter R, Theussl HC, Parzer SB, Moriggl R, Wagner EF, Sexl V. Szremska AP, et al. Among authors: moriggl r. Blood. 2003 Dec 1;102(12):4159-65. doi: 10.1182/blood-2003-03-0915. Epub 2003 Aug 7. Blood. 2003. PMID: 12907453 Free article.
Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML): evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides.
Aichberger KJ, Mayerhofer M, Krauth MT, Skvara H, Florian S, Sonneck K, Akgul C, Derdak S, Pickl WF, Wacheck V, Selzer E, Monia BP, Moriggl R, Valent P, Sillaber C. Aichberger KJ, et al. Among authors: moriggl r. Blood. 2005 Apr 15;105(8):3303-11. doi: 10.1182/blood-2004-02-0749. Epub 2004 Dec 30. Blood. 2005. PMID: 15626746 Free article.
Stat5 tetramer formation is associated with leukemogenesis.
Moriggl R, Sexl V, Kenner L, Duntsch C, Stangl K, Gingras S, Hoffmeyer A, Bauer A, Piekorz R, Wang D, Bunting KD, Wagner EF, Sonneck K, Valent P, Ihle JN, Beug H. Moriggl R, et al. Cancer Cell. 2005 Jan;7(1):87-99. doi: 10.1016/j.ccr.2004.12.010. Cancer Cell. 2005. PMID: 15652752 Free article.
Autocrine PDGFR signaling promotes mammary cancer metastasis.
Jechlinger M, Sommer A, Moriggl R, Seither P, Kraut N, Capodiecci P, Donovan M, Cordon-Cardo C, Beug H, Grünert S. Jechlinger M, et al. Among authors: moriggl r. J Clin Invest. 2006 Jun;116(6):1561-70. doi: 10.1172/JCI24652. J Clin Invest. 2006. PMID: 16741576 Free PMC article.
STAT1 acts as a tumor promoter for leukemia development.
Kovacic B, Stoiber D, Moriggl R, Weisz E, Ott RG, Kreibich R, Levy DE, Beug H, Freissmuth M, Sexl V. Kovacic B, et al. Among authors: moriggl r. Cancer Cell. 2006 Jul;10(1):77-87. doi: 10.1016/j.ccr.2006.05.025. Cancer Cell. 2006. PMID: 16843267 Free article.
220 results