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In vivo contribution of serine proteases to the proteolytic activation of γENaC in aldosterone-infused rats.
Uchimura K, Kakizoe Y, Onoue T, Hayata M, Morinaga J, Yamazoe R, Ueda M, Mizumoto T, Adachi M, Miyoshi T, Shiraishi N, Sakai Y, Tomita K, Kitamura K. Uchimura K, et al. Among authors: morinaga j. Am J Physiol Renal Physiol. 2012 Oct;303(7):F939-43. doi: 10.1152/ajprenal.00705.2011. Epub 2012 Jul 25. Am J Physiol Renal Physiol. 2012. PMID: 22832922 Free article.
Effect of a serine protease inhibitor on the progression of chronic renal failure.
Hayata M, Kakizoe Y, Uchimura K, Morinaga J, Yamazoe R, Mizumoto T, Onoue T, Ueda M, Shiraishi N, Adachi M, Miyoshi T, Sakai Y, Tomita K, Kitamura K. Hayata M, et al. Among authors: morinaga j. Am J Physiol Renal Physiol. 2012 Oct 15;303(8):F1126-35. doi: 10.1152/ajprenal.00706.2011. Epub 2012 Jul 25. Am J Physiol Renal Physiol. 2012. PMID: 22832926 Free article.
The antifibrotic effect of a serine protease inhibitor in the kidney.
Morinaga J, Kakizoe Y, Miyoshi T, Onoue T, Ueda M, Mizumoto T, Yamazoe R, Uchimura K, Hayata M, Shiraishi N, Adachi M, Sakai Y, Tomita K, Kitamura K. Morinaga J, et al. Am J Physiol Renal Physiol. 2013 Jul 15;305(2):F173-81. doi: 10.1152/ajprenal.00586.2012. Epub 2013 May 22. Am J Physiol Renal Physiol. 2013. PMID: 23698112 Free article.
Angiopoietin-like protein 2 increases renal fibrosis by accelerating transforming growth factor-β signaling in chronic kidney disease.
Morinaga J, Kadomatsu T, Miyata K, Endo M, Terada K, Tian Z, Sugizaki T, Tanigawa H, Zhao J, Zhu S, Sato M, Araki K, Iyama K, Tomita K, Mukoyama M, Tomita K, Kitamura K, Oike Y. Morinaga J, et al. Kidney Int. 2016 Feb;89(2):327-41. doi: 10.1016/j.kint.2015.12.021. Epub 2016 Jan 1. Kidney Int. 2016. PMID: 26806834 Free article.
Combination therapy with renin-angiotensin-aldosterone system inhibitor telmisartan and serine protease inhibitor camostat mesilate provides further renoprotection in a rat chronic kidney disease model.
Narita Y, Ueda M, Uchimura K, Kakizoe Y, Miyasato Y, Mizumoto T, Morinaga J, Hayata M, Nakagawa T, Adachi M, Miyoshi T, Sakai Y, Kadowaki D, Hirata S, Mukoyama M, Kitamura K. Narita Y, et al. Among authors: morinaga j. J Pharmacol Sci. 2016 Feb;130(2):110-6. doi: 10.1016/j.jphs.2016.01.003. Epub 2016 Jan 20. J Pharmacol Sci. 2016. PMID: 26887332 Free article.
ANGPTL2 activity in cardiac pathologies accelerates heart failure by perturbing cardiac function and energy metabolism.
Tian Z, Miyata K, Kadomatsu T, Horiguchi H, Fukushima H, Tohyama S, Ujihara Y, Okumura T, Yamaguchi S, Zhao J, Endo M, Morinaga J, Sato M, Sugizaki T, Zhu S, Terada K, Sakaguchi H, Komohara Y, Takeya M, Takeda N, Araki K, Manabe I, Fukuda K, Otsu K, Wada J, Murohara T, Mohri S, Yamashita JK, Sano M, Oike Y. Tian Z, et al. Among authors: morinaga j. Nat Commun. 2016 Sep 28;7:13016. doi: 10.1038/ncomms13016. Nat Commun. 2016. PMID: 27677409 Free PMC article.
A serine protease inhibitor attenuates aldosterone-induced kidney injuries via the suppression of plasmin activity.
Kakizoe Y, Miyasato Y, Onoue T, Nakagawa T, Hayata M, Uchimura K, Morinaga J, Mizumoto T, Adachi M, Miyoshi T, Sakai Y, Tomita K, Mukoyama M, Kitamura K. Kakizoe Y, et al. Among authors: morinaga j. J Pharmacol Sci. 2016 Oct;132(2):145-153. doi: 10.1016/j.jphs.2016.09.005. Epub 2016 Sep 30. J Pharmacol Sci. 2016. PMID: 27773435 Free article.
Circulating angiopoietin-like protein 2 levels and mortality risk in patients receiving maintenance hemodialysis: a prospective cohort study.
Morinaga J, Kakuma T, Fukami H, Hayata M, Uchimura K, Mizumoto T, Kakizoe Y, Miyoshi T, Shiraishi N, Adachi M, Izumi Y, Kuwabara T, Okadome Y, Sato M, Horiguchi H, Sugizaki T, Kadomatsu T, Miyata K, Tajiri S, Tajiri T, Tomita K, Kitamura K, Oike Y, Mukoyama M. Morinaga J, et al. Nephrol Dial Transplant. 2020 May 1;35(5):854-860. doi: 10.1093/ndt/gfz236. Nephrol Dial Transplant. 2020. PMID: 31840173
74 results