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Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo.
Formentini L, Moroni F, Chiarugi A. Formentini L, et al. Among authors: moroni f. Biochem Pharmacol. 2009 May 15;77(10):1612-20. doi: 10.1016/j.bcp.2009.02.017. Epub 2009 Mar 5. Biochem Pharmacol. 2009. PMID: 19426698
Effects of PARP-1 Deficiency and Histamine H4 Receptor Inhibition in an Inflammatory Model of Lung Fibrosis in Mice.
Durante M, Sgambellone S, Lanzi C, Nardini P, Pini A, Moroni F, Masini E, Lucarini L. Durante M, et al. Among authors: moroni f. Front Pharmacol. 2019 May 16;10:525. doi: 10.3389/fphar.2019.00525. eCollection 2019. Front Pharmacol. 2019. PMID: 31164820 Free PMC article.
18β-glycyrrhetic acid inhibits immune activation triggered by HMGB1, a pro-inflammatory protein found in the tear fluid during conjunctivitis and blepharitis.
Cavone L, Muzzi M, Mencucci R, Sparatore B, Pedrazzi M, Moroni F, Chiarugi A. Cavone L, et al. Among authors: moroni f. Ocul Immunol Inflamm. 2011 Jun;19(3):180-5. doi: 10.3109/09273948.2010.538121. Epub 2011 Mar 22. Ocul Immunol Inflamm. 2011. PMID: 21426233
Poly(ADP-ribose) polymerase-1 is a nuclear epigenetic regulator of mitochondrial DNA repair and transcription.
Lapucci A, Pittelli M, Rapizzi E, Felici R, Moroni F, Chiarugi A. Lapucci A, et al. Among authors: moroni f. Mol Pharmacol. 2011 Jun;79(6):932-40. doi: 10.1124/mol.110.070110. Epub 2011 Mar 11. Mol Pharmacol. 2011. PMID: 21441600
Neither energy collapse nor transcription underlie in vitro neurotoxicity of poly(ADP-ribose) polymerase hyper-activation.
Fossati S, Cipriani G, Moroni F, Chiarugi A. Fossati S, et al. Among authors: moroni f. Neurochem Int. 2007 Jan;50(1):203-10. doi: 10.1016/j.neuint.2006.08.009. Epub 2006 Oct 18. Neurochem Int. 2007. PMID: 17052800
Differential role of poly(ADP-ribose) polymerase-1in apoptotic and necrotic neuronal death induced by mild or intense NMDA exposure in vitro.
Meli E, Pangallo M, Picca R, Baronti R, Moroni F, Pellegrini-Giampietro DE. Meli E, et al. Among authors: moroni f. Mol Cell Neurosci. 2004 Jan;25(1):172-80. doi: 10.1016/j.mcn.2003.09.016. Mol Cell Neurosci. 2004. PMID: 14962750
Novel isoquinolinone-derived inhibitors of poly(ADP-ribose) polymerase-1: pharmacological characterization and neuroprotective effects in an in vitro model of cerebral ischemia.
Chiarugi A, Meli E, Calvani M, Picca R, Baronti R, Camaioni E, Costantino G, Marinozzi M, Pellegrini-Giampietro DE, Pellicciari R, Moroni F. Chiarugi A, et al. Among authors: moroni f. J Pharmacol Exp Ther. 2003 Jun;305(3):943-9. doi: 10.1124/jpet.103.048934. Epub 2003 Feb 20. J Pharmacol Exp Ther. 2003. PMID: 12606624
Comet assay as a novel approach for studying DNA damage in focal cerebral ischemia: differential effects of NMDA receptor antagonists and poly(ADP-ribose) polymerase inhibitors.
Giovannelli L, Cozzi A, Guarnieri I, Dolara P, Moroni F. Giovannelli L, et al. Among authors: moroni f. J Cereb Blood Flow Metab. 2002 Jun;22(6):697-704. doi: 10.1097/00004647-200206000-00008. J Cereb Blood Flow Metab. 2002. PMID: 12045668
Mini E, Landini I, Lucarini L, Lapucci A, Napoli C, Perrone G, Tassi R, Masini E, Moroni F, Nobili S. Mini E, et al. Among authors: moroni f. Oncol Res. 2018 Mar 5;26(2):333-334. doi: 10.3727/096504018X15187172557369. Oncol Res. 2018. PMID: 29514732
Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases.
Berger NA, Besson VC, Boulares AH, Bürkle A, Chiarugi A, Clark RS, Curtin NJ, Cuzzocrea S, Dawson TM, Dawson VL, Haskó G, Liaudet L, Moroni F, Pacher P, Radermacher P, Salzman AL, Snyder SH, Soriano FG, Strosznajder RP, Sümegi B, Swanson RA, Szabo C. Berger NA, et al. Among authors: moroni f. Br J Pharmacol. 2018 Jan;175(2):192-222. doi: 10.1111/bph.13748. Epub 2017 Mar 26. Br J Pharmacol. 2018. PMID: 28213892 Free PMC article. Review.
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