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Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury.
Thyfault JP, Rector RS, Uptergrove GM, Borengasser SJ, Morris EM, Wei Y, Laye MJ, Burant CF, Qi NR, Ridenhour SE, Koch LG, Britton SL, Ibdah JA. Thyfault JP, et al. Among authors: morris em. J Physiol. 2009 Apr 15;587(Pt 8):1805-16. doi: 10.1113/jphysiol.2009.169060. Epub 2009 Feb 23. J Physiol. 2009. PMID: 19237421 Free PMC article.
Changes in skeletal muscle mitochondria in response to the development of type 2 diabetes or prevention by daily wheel running in hyperphagic OLETF rats.
Rector RS, Uptergrove GM, Borengasser SJ, Mikus CR, Morris EM, Naples SP, Laye MJ, Laughlin MH, Booth FW, Ibdah JA, Thyfault JP. Rector RS, et al. Among authors: morris em. Am J Physiol Endocrinol Metab. 2010 Jun;298(6):E1179-87. doi: 10.1152/ajpendo.00703.2009. Epub 2010 Mar 16. Am J Physiol Endocrinol Metab. 2010. PMID: 20233940 Free PMC article.
Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model.
Rector RS, Thyfault JP, Uptergrove GM, Morris EM, Naples SP, Borengasser SJ, Mikus CR, Laye MJ, Laughlin MH, Booth FW, Ibdah JA. Rector RS, et al. Among authors: morris em. J Hepatol. 2010 May;52(5):727-36. doi: 10.1016/j.jhep.2009.11.030. Epub 2010 Mar 4. J Hepatol. 2010. PMID: 20347174 Free PMC article.
Mitochondria and redox signaling in steatohepatitis.
Morris EM, Rector RS, Thyfault JP, Ibdah JA. Morris EM, et al. Antioxid Redox Signal. 2011 Jul 15;15(2):485-504. doi: 10.1089/ars.2010.3795. Epub 2011 Apr 26. Antioxid Redox Signal. 2011. PMID: 21128703 Free PMC article. Review.
109 results