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Genetically decreased vitamin D and risk of Alzheimer disease.
Mokry LE, Ross S, Morris JA, Manousaki D, Forgetta V, Richards JB. Mokry LE, et al. Among authors: morris ja. Neurology. 2016 Dec 13;87(24):2567-2574. doi: 10.1212/WNL.0000000000003430. Epub 2016 Nov 16. Neurology. 2016. PMID: 27856775 Free PMC article.
Epigenome-wide Association of DNA Methylation in Whole Blood With Bone Mineral Density.
Morris JA, Tsai PC, Joehanes R, Zheng J, Trajanoska K, Soerensen M, Forgetta V, Castillo-Fernandez JE, Frost M, Spector TD, Christensen K, Christiansen L, Rivadeneira F, Tobias JH, Evans DM, Kiel DP, Hsu YH, Richards JB, Bell JT. Morris JA, et al. J Bone Miner Res. 2017 Aug;32(8):1644-1650. doi: 10.1002/jbmr.3148. Epub 2017 May 8. J Bone Miner Res. 2017. PMID: 28394087 Free PMC article. Clinical Trial.
Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis.
Kemp JP, Morris JA, Medina-Gomez C, Forgetta V, Warrington NM, Youlten SE, Zheng J, Gregson CL, Grundberg E, Trajanoska K, Logan JG, Pollard AS, Sparkes PC, Ghirardello EJ, Allen R, Leitch VD, Butterfield NC, Komla-Ebri D, Adoum AT, Curry KF, White JK, Kussy F, Greenlaw KM, Xu C, Harvey NC, Cooper C, Adams DJ, Greenwood CMT, Maurano MT, Kaptoge S, Rivadeneira F, Tobias JH, Croucher PI, Ackert-Bicknell CL, Bassett JHD, Williams GR, Richards JB, Evans DM. Kemp JP, et al. Among authors: morris ja. Nat Genet. 2017 Oct;49(10):1468-1475. doi: 10.1038/ng.3949. Epub 2017 Sep 4. Nat Genet. 2017. PMID: 28869591 Free PMC article.
Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.
Willems SM, Wright DJ, Day FR, Trajanoska K, Joshi PK, Morris JA, Matteini AM, Garton FC, Grarup N, Oskolkov N, Thalamuthu A, Mangino M, Liu J, Demirkan A, Lek M, Xu L, Wang G, Oldmeadow C, Gaulton KJ, Lotta LA, Miyamoto-Mikami E, Rivas MA, White T, Loh PR, Aadahl M, Amin N, Attia JR, Austin K, Benyamin B, Brage S, Cheng YC, Cięszczyk P, Derave W, Eriksson KF, Eynon N, Linneberg A, Lucia A, Massidda M, Mitchell BD, Miyachi M, Murakami H, Padmanabhan S, Pandey A, Papadimitriou I, Rajpal DK, Sale C, Schnurr TM, Sessa F, Shrine N, Tobin MD, Varley I, Wain LV, Wray NR, Lindgren CM, MacArthur DG, Waterworth DM, McCarthy MI, Pedersen O, Khaw KT, Kiel DP; GEFOS Any-Type of Fracture Consortium, Pitsiladis Y, Fuku N, Franks PW, North KN, van Duijn CM, Mather KA, Hansen T, Hansson O, Spector T, Murabito JM, Richards JB, Rivadeneira F, Langenberg C, Perry JRB, Wareham NJ, Scott RA. Willems SM, et al. Among authors: morris ja. Nat Commun. 2017 Jul 12;8:16015. doi: 10.1038/ncomms16015. Nat Commun. 2017. PMID: 29313844 Free PMC article.
FAM210A is a novel determinant of bone and muscle structure and strength.
Tanaka KI, Xue Y, Nguyen-Yamamoto L, Morris JA, Kanazawa I, Sugimoto T, Wing SS, Richards JB, Goltzman D. Tanaka KI, et al. Among authors: morris ja. Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3759-E3768. doi: 10.1073/pnas.1719089115. Epub 2018 Apr 4. Proc Natl Acad Sci U S A. 2018. PMID: 29618611 Free PMC article.
Genome-wide association study of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes.
Gregson CL, Newell F, Leo PJ, Clark GR, Paternoster L, Marshall M, Forgetta V, Morris JA, Ge B, Bao X, Duncan Bassett JH, Williams GR, Youlten SE, Croucher PI, Davey Smith G, Evans DM, Kemp JP, Brown MA, Tobias JH, Duncan EL. Gregson CL, et al. Among authors: morris ja. Bone. 2018 Sep;114:62-71. doi: 10.1016/j.bone.2018.06.001. Epub 2018 Jun 5. Bone. 2018. PMID: 29883787 Free PMC article.
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