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Therapy of peritoneal carcinomatosis from colon cancer with oncolytic adenoviruses.
Wildner O, Morris JC. Wildner O, et al. Among authors: morris jc. J Gene Med. 2000 Sep-Oct;2(5):353-60. doi: 10.1002/1521-2254(200009/10)2:5<353::AID-JGM130>3.0.CO;2-G. J Gene Med. 2000. PMID: 11045429
Antitumor activity and metabolic activation of N-methanocarbathymidine, a novel thymidine analogue with a pseudosugar rigidly fixed in the northern conformation, in murine colon cancer cells expressing herpes simplex thymidine kinase.
Noy R, Ben-Zvi Z, Manor E, Candotti F, Morris JC, Ford H Jr, Marquez VE, Johns DG, Agbaria R. Noy R, et al. Among authors: morris jc. Mol Cancer Ther. 2002 Jun;1(8):585-93. Mol Cancer Ther. 2002. PMID: 12479218
In situ generation of pseudotyped retroviral progeny by adenovirus-mediated transduction of tumor cells enhances the killing effect of HSV-tk suicide gene therapy in vitro and in vivo.
Okada T, Caplen NJ, Ramsey WJ, Onodera M, Shimazaki K, Nomoto T, Ajalli R, Wildner O, Morris J, Kume A, Hamada H, Blaese RM, Ozawa K. Okada T, et al. Among authors: morris j. J Gene Med. 2004 Mar;6(3):288-99. doi: 10.1002/jgm.490. J Gene Med. 2004. PMID: 15026990
Therapy of head and neck squamous cell carcinoma with an oncolytic adenovirus expressing HSV-tk.
Morris JC, Wildner O. Morris JC, et al. Mol Ther. 2000 Jan;1(1):56-62. doi: 10.1006/mthe.1999.0014. Mol Ther. 2000. PMID: 10933912
A phase I study of intralesional administration of an adenovirus vector expressing the HSV-1 thymidine kinase gene (AdV.RSV-TK) in combination with escalating doses of ganciclovir in patients with cutaneous metastatic malignant melanoma.
Morris JC, Ramsey WJ, Wildner O, Muslow HA, Aguilar-Cordova E, Blaese RM. Morris JC, et al. Hum Gene Ther. 2000 Feb 10;11(3):487-503. doi: 10.1089/10430340050015950. Hum Gene Ther. 2000. PMID: 10697123 Clinical Trial. No abstract available.
Adenoviral vectors capable of replication improve the efficacy of HSVtk/GCV suicide gene therapy of cancer.
Wildner O, Morris JC, Vahanian NN, Ford H Jr, Ramsey WJ, Blaese RM. Wildner O, et al. Among authors: morris jc. Gene Ther. 1999 Jan;6(1):57-62. doi: 10.1038/sj.gt.3300810. Gene Ther. 1999. PMID: 10341876
Lentivirus-mediated gene transfer into hematopoietic repopulating cells in baboons.
Horn PA, Morris JC, Bukovsky AA, Andrews RG, Naldini L, Kurre P, Kiem HP. Horn PA, et al. Among authors: morris jc. Gene Ther. 2002 Nov;9(21):1464-71. doi: 10.1038/sj.gt.3301820. Gene Ther. 2002. PMID: 12378409
Vaccination with tumor cells expressing IL-15 and IL-15Rα inhibits murine breast and prostate cancer.
Morris JC, Ramlogan-Steel CA, Yu P, Black BA, Mannan P, Allison JP, Waldmann TA, Steel JC. Morris JC, et al. Gene Ther. 2014 Apr;21(4):393-401. doi: 10.1038/gt.2014.10. Epub 2014 Feb 27. Gene Ther. 2014. PMID: 24572789 Free PMC article.
Trans-complementing adenoviral vectors for oncolytic therapy of malignant melanoma.
Wolkersdörfer GW, Morris JC, Ehninger G, Ramsey WJ. Wolkersdörfer GW, et al. Among authors: morris jc. J Gene Med. 2004 Jun;6(6):652-62. doi: 10.1002/jgm.551. J Gene Med. 2004. PMID: 15170736
The role of the E1B 55 kDa gene product in oncolytic adenoviral vectors expressing herpes simplex virus-tk: assessment of antitumor efficacy and toxicity.
Wildner O, Morris JC. Wildner O, et al. Among authors: morris jc. Cancer Res. 2000 Aug 1;60(15):4167-74. Cancer Res. 2000. PMID: 10945625
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