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Isolation and Characterization of Reticuline N-Methyltransferase Involved in Biosynthesis of the Aporphine Alkaloid Magnoflorine in Opium Poppy.
Morris JS, Facchini PJ. Morris JS, et al. J Biol Chem. 2016 Nov 4;291(45):23416-23427. doi: 10.1074/jbc.M116.750893. Epub 2016 Sep 15. J Biol Chem. 2016. PMID: 27634038 Free PMC article.
Transcriptome analysis of 20 taxonomically related benzylisoquinoline alkaloid-producing plants.
Hagel JM, Morris JS, Lee EJ, Desgagné-Penix I, Bross CD, Chang L, Chen X, Farrow SC, Zhang Y, Soh J, Sensen CW, Facchini PJ. Hagel JM, et al. BMC Plant Biol. 2015 Sep 18;15:227. doi: 10.1186/s12870-015-0596-0. BMC Plant Biol. 2015. PMID: 26384972 Free PMC article.
Plug-and-Play Benzylisoquinoline Alkaloid Biosynthetic Gene Discovery in Engineered Yeast.
Morris JS, Dastmalchi M, Li J, Chang L, Chen X, Hagel JM, Facchini PJ. Morris JS, et al. Methods Enzymol. 2016;575:143-78. doi: 10.1016/bs.mie.2016.03.023. Epub 2016 Apr 25. Methods Enzymol. 2016. PMID: 27417928
Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism.
Torres MA, Hoffarth E, Eugenio L, Savtchouk J, Chen X, Morris JS, Facchini PJ, Ng KK. Torres MA, et al. J Biol Chem. 2016 Nov 4;291(45):23403-23415. doi: 10.1074/jbc.M116.747261. Epub 2016 Aug 29. J Biol Chem. 2016. PMID: 27573242 Free PMC article.
An N-methyltransferase from Ephedra sinica catalyzing the formation of ephedrine and pseudoephedrine enables microbial phenylalkylamine production.
Morris JS, Groves RA, Hagel JM, Facchini PJ. Morris JS, et al. J Biol Chem. 2018 Aug 31;293(35):13364-13376. doi: 10.1074/jbc.RA118.004067. Epub 2018 Jun 21. J Biol Chem. 2018. PMID: 29929980 Free PMC article.
Structure-function studies of tetrahydroprotoberberine N-methyltransferase reveal the molecular basis of stereoselective substrate recognition.
Lang DE, Morris JS, Rowley M, Torres MA, Maksimovich VA, Facchini PJ, Ng KKS. Lang DE, et al. J Biol Chem. 2019 Oct 4;294(40):14482-14498. doi: 10.1074/jbc.RA119.009214. Epub 2019 Aug 7. J Biol Chem. 2019. PMID: 31395658
PR10/Bet v 1-like proteins as novel contributors to plant biochemical diversity.
Morris JS, Caldo KM, Liang S, Facchini P. Morris JS, et al. Chembiochem. 2020 Jul 23. doi: 10.1002/cbic.202000354. Online ahead of print. Chembiochem. 2020. PMID: 32700448
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