Morris SJ - Search Results

1

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination.

Bertrand MJ, Milutinovic S, Dickson KM, Ho WC, Boudreault A, Durkin J, Gillard JW, Jaquith JB, Morris SJ, Barker PA. Bertrand MJ, et al. Among authors: morris sj. Mol Cell. 2008 Jun 20;30(6):689-700. doi: 10.1016/j.molcel.2008.05.014. Mol Cell. 2008. PMID: 18570872 Free article.

2

AEG3482 is an antiapoptotic compound that inhibits Jun kinase activity and cell death through induced expression of heat shock protein 70.

Salehi AH, Morris SJ, Ho WC, Dickson KM, Doucet G, Milutinovic S, Durkin J, Gillard JW, Barker PA. Salehi AH, et al. Among authors: morris sj. Chem Biol. 2006 Feb;13(2):213-23. doi: 10.1016/j.chembiol.2005.11.012. Chem Biol. 2006. PMID: 16492569

3

Preclinical characterization of AEG35156/GEM 640, a second-generation antisense oligonucleotide targeting X-linked inhibitor of apoptosis.

LaCasse EC, Cherton-Horvat GG, Hewitt KE, Jerome LJ, Morris SJ, Kandimalla ER, Yu D, Wang H, Wang W, Zhang R, Agrawal S, Gillard JW, Durkin JP. LaCasse EC, et al. Among authors: morris sj. Clin Cancer Res. 2006 Sep 1;12(17):5231-41. doi: 10.1158/1078-0432.CCR-06-0608. Clin Cancer Res. 2006. PMID: 16951243

4

Cytoprotective effects of IAPs revealed by a small molecule antagonist.

Galbán S, Hwang C, Rumble JM, Oetjen KA, Wright CW, Boudreault A, Durkin J, Gillard JW, Jaquith JB, Morris SJ, Duckett CS. Galbán S, et al. Among authors: morris sj. Biochem J. 2009 Feb 1;417(3):765-71. doi: 10.1042/BJ20081677. Biochem J. 2009. PMID: 18851715 Free PMC article.

5

X-linked inhibitor of apoptosis regulates T cell effector function.

Zehntner SP, Bourbonnière L, Moore CS, Morris SJ, Methot D, St Jean M, Lacasse E, Hebb AL, Robertson GS, Durkin J, Gillard JW, Owens T. Zehntner SP, et al. Among authors: morris sj. J Immunol. 2007 Dec 1;179(11):7553-60. doi: 10.4049/jimmunol.179.11.7553. J Immunol. 2007. PMID: 18025200

6

K252a and CEP1347 are neuroprotective compounds that inhibit mixed-lineage kinase-3 and induce activation of Akt and ERK.

Roux PP, Dorval G, Boudreau M, Angers-Loustau A, Morris SJ, Makkerh J, Barker PA. Roux PP, et al. Among authors: morris sj. J Biol Chem. 2002 Dec 20;277(51):49473-80. doi: 10.1074/jbc.M203428200. Epub 2002 Oct 17. J Biol Chem. 2002. PMID: 12388555 Free article.

7

The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.

Zahreddine HA, Culjkovic-Kraljacic B, Assouline S, Gendron P, Romeo AA, Morris SJ, Cormack G, Jaquith JB, Cerchietti L, Cocolakis E, Amri A, Bergeron J, Leber B, Becker MW, Pei S, Jordan CT, Miller WH, Borden KL. Zahreddine HA, et al. Among authors: morris sj. Nature. 2014 Jul 3;511(7507):90-3. doi: 10.1038/nature13283. Epub 2014 May 28. Nature. 2014. PMID: 24870236 Free PMC article.

8

Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics.

McManus DC, Lefebvre CA, Cherton-Horvat G, St-Jean M, Kandimalla ER, Agrawal S, Morris SJ, Durkin JP, Lacasse EC. McManus DC, et al. Among authors: morris sj. Oncogene. 2004 Oct 21;23(49):8105-17. doi: 10.1038/sj.onc.1207967. Oncogene. 2004. PMID: 15378029

9

Phase I trial of AEG35156 administered as a 7-day and 3-day continuous intravenous infusion in patients with advanced refractory cancer.

Dean E, Jodrell D, Connolly K, Danson S, Jolivet J, Durkin J, Morris S, Jowle D, Ward T, Cummings J, Dickinson G, Aarons L, Lacasse E, Robson L, Dive C, Ranson M. Dean E, et al. J Clin Oncol. 2009 Apr 1;27(10):1660-6. doi: 10.1200/JCO.2008.19.5677. Epub 2009 Feb 23. J Clin Oncol. 2009. PMID: 19237630 Clinical Trial.

10

Neurotrophin-4, alone or heterodimerized with brain-derived neurotrophic factor, is sorted to the constitutive secretory pathway.

Hibbert AP, Morris SJ, Seidah NG, Murphy RA. Hibbert AP, et al. Among authors: morris sj. J Biol Chem. 2003 Nov 28;278(48):48129-36. doi: 10.1074/jbc.M300961200. Epub 2003 Sep 11. J Biol Chem. 2003. PMID: 12970359 Free article.

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