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Anti-tumor effect of CT-322 as an adnectin inhibitor of vascular endothelial growth factor receptor-2.
Mamluk R, Carvajal IM, Morse BA, Wong H, Abramowitz J, Aslanian S, Lim AC, Gokemeijer J, Storek MJ, Lee J, Gosselin M, Wright MC, Camphausen RT, Wang J, Chen Y, Miller K, Sanders K, Short S, Sperinde J, Prasad G, Williams S, Kerbel R, Ebos J, Mutsaers A, Mendlein JD, Harris AS, Furfine ES. Mamluk R, et al. Among authors: morse ba. MAbs. 2010 Mar-Apr;2(2):199-208. doi: 10.4161/mabs.2.2.11304. MAbs. 2010. PMID: 20190562 Free PMC article.
A fibronectin scaffold approach to bispecific inhibitors of epidermal growth factor receptor and insulin-like growth factor-I receptor.
Emanuel SL, Engle LJ, Chao G, Zhu RR, Cao C, Lin Z, Yamniuk AP, Hosbach J, Brown J, Fitzpatrick E, Gokemeijer J, Morin P, Morse BA, Carvajal IM, Fabrizio D, Wright MC, Das Gupta R, Gosselin M, Cataldo D, Ryseck RP, Doyle ML, Wong TW, Camphausen RT, Cload ST, Marsh HN, Gottardis MM, Furfine ES. Emanuel SL, et al. Among authors: morse ba. MAbs. 2011 Jan-Feb;3(1):38-48. doi: 10.4161/mabs.3.1.14168. Epub 2011 Jan 1. MAbs. 2011. PMID: 21099371 Free PMC article.
CT322, a VEGFR-2 antagonist, demonstrates anti-glioma efficacy in orthotopic brain tumor model as a single agent or in combination with temozolomide and radiation therapy.
Waters JD, Sanchez C, Sahin A, Futalan D, Gonda DD, Scheer JK, Akers J, Palanichamy K, Waterman P, Chakravarti A, Weissleder R, Morse B, Marsh N, Furfine E, Chen CC, Carvajal I, Carter BS. Waters JD, et al. J Neurooncol. 2012 Oct;110(1):37-48. doi: 10.1007/s11060-012-0948-7. Epub 2012 Aug 9. J Neurooncol. 2012. PMID: 22875706 Free PMC article.
16 results