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Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development.
Steimle JD, Rankin SA, Slagle CE, Bekeny J, Rydeen AB, Chan SS, Kweon J, Yang XH, Ikegami K, Nadadur RD, Rowton M, Hoffmann AD, Lazarevic S, Thomas W, Boyle Anderson EAT, Horb ME, Luna-Zurita L, Ho RK, Kyba M, Jensen B, Zorn AM, Conlon FL, Moskowitz IP. Steimle JD, et al. Among authors: moskowitz ip. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10615-E10624. doi: 10.1073/pnas.1811624115. Epub 2018 Oct 23. Proc Natl Acad Sci U S A. 2018. PMID: 30352852 Free PMC article.
sonic hedgehog is required in pulmonary endoderm for atrial septation.
Hoffmann AD, Peterson MA, Friedland-Little JM, Anderson SA, Moskowitz IP. Hoffmann AD, et al. Among authors: moskowitz ip. Development. 2009 May;136(10):1761-70. doi: 10.1242/dev.034157. Epub 2009 Apr 15. Development. 2009. PMID: 19369393 Free PMC article.
TBX5 drives Scn5a expression to regulate cardiac conduction system function.
Arnolds DE, Liu F, Fahrenbach JP, Kim GH, Schillinger KJ, Smemo S, McNally EM, Nobrega MA, Patel VV, Moskowitz IP. Arnolds DE, et al. Among authors: moskowitz ip. J Clin Invest. 2012 Jul;122(7):2509-18. doi: 10.1172/JCI62617. Epub 2012 Jun 25. J Clin Invest. 2012. PMID: 22728936 Free PMC article.
84 results