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Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency.
Ehinger JK, Piel S, Ford R, Karlsson M, Sjövall F, Frostner EÅ, Morota S, Taylor RW, Turnbull DM, Cornell C, Moss SJ, Metzsch C, Hansson MJ, Fliri H, Elmér E. Ehinger JK, et al. Among authors: moss sj. Nat Commun. 2016 Aug 9;7:12317. doi: 10.1038/ncomms12317. Nat Commun. 2016. PMID: 27502960 Free PMC article.
Bioengineering and semisynthesis of an optimized cyclophilin inhibitor for treatment of chronic viral infection.
Hansson MJ, Moss SJ, Bobardt M, Chatterji U, Coates N, Garcia-Rivera JA, Elmér E, Kendrew S, Leyssen P, Neyts J, Nur-E-Alam M, Warneck T, Wilkinson B, Gallay P, Gregory MA. Hansson MJ, et al. Among authors: moss sj. Chem Biol. 2015 Feb 19;22(2):285-92. doi: 10.1016/j.chembiol.2014.10.023. Epub 2015 Jan 22. Chem Biol. 2015. PMID: 25619934 Free PMC article.
Diversity oriented biosynthesis via accelerated evolution of modular gene clusters.
Wlodek A, Kendrew SG, Coates NJ, Hold A, Pogwizd J, Rudder S, Sheehan LS, Higginbotham SJ, Stanley-Smith AE, Warneck T, Nur-E-Alam M, Radzom M, Martin CJ, Overvoorde L, Samborskyy M, Alt S, Heine D, Carter GT, Graziani EI, Koehn FE, McDonald L, Alanine A, Rodríguez Sarmiento RM, Chao SK, Ratni H, Steward L, Norville IH, Sarkar-Tyson M, Moss SJ, Leadlay PF, Wilkinson B, Gregory MA. Wlodek A, et al. Among authors: moss sj. Nat Commun. 2017 Oct 31;8(1):1206. doi: 10.1038/s41467-017-01344-3. Nat Commun. 2017. PMID: 29089518 Free PMC article.
Preclinical characterization of naturally occurring polyketide cyclophilin inhibitors from the sanglifehrin family.
Gregory MA, Bobardt M, Obeid S, Chatterji U, Coates NJ, Foster T, Gallay P, Leyssen P, Moss SJ, Neyts J, Nur-e-Alam M, Paeshuyse J, Piraee M, Suthar D, Warneck T, Zhang MQ, Wilkinson B. Gregory MA, et al. Among authors: moss sj. Antimicrob Agents Chemother. 2011 May;55(5):1975-81. doi: 10.1128/AAC.01627-10. Epub 2011 Mar 7. Antimicrob Agents Chemother. 2011. PMID: 21383094 Free PMC article.
389 results