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A novel 1 beta-methylcarbapenem antibiotic, S-4661. Synthesis and structure-activity relationships of 2-(5-substituted pyrrolidin-3-ylthio)-1 beta-methylcarbapenems.
Iso Y, Irie T, Nishino Y, Motokawa K, Nishitani Y. Iso Y, et al. J Antibiot (Tokyo). 1996 Feb;49(2):199-209. doi: 10.7164/antibiotics.49.199. J Antibiot (Tokyo). 1996. PMID: 8621362
Novel antibacterial macrolides: synthesis of 15-membered diolides.
Ohara T, Kume M, Narukawa Y, Motokawa K, Uotani K, Nakai H. Ohara T, et al. J Org Chem. 2002 Dec 27;67(26):9146-52. doi: 10.1021/jo020458e. J Org Chem. 2002. PMID: 12492314
Asparenomycins A, B and C, new carbapenem antibiotics. IV. Antibacterial activity.
Kimura Y, Motokawa K, Nagata H, Kameda Y, Matsuura S, Mayama M, Yoshida T. Kimura Y, et al. J Antibiot (Tokyo). 1982 Jan;35(1):32-8. doi: 10.7164/antibiotics.35.32. J Antibiot (Tokyo). 1982. PMID: 7068514
Synthesis and biological properties of 7 beta-[(Z)-2-(2-amino-4-thiazolyl)-4-carboxy-2-butenoylamino]-3-cephem- 4-carboxylic acid (7432-S), a new oral cephem antibiotic.
Hamashima Y, Kubota T, Minami K, Ishikura K, Konoike T, Yoshioka M, Yoshida T, Nakashimizu H, Motokawa K. Hamashima Y, et al. J Antibiot (Tokyo). 1987 Oct;40(10):1468-70. doi: 10.7164/antibiotics.40.1468. J Antibiot (Tokyo). 1987. PMID: 3680016 No abstract available.
Antibiotic A-130, isolation and characterization.
Kubota T, Hinoh G, Mayama M, Motokawa K, Yasuda Y. Kubota T, et al. J Antibiot (Tokyo). 1975 Dec;28(12):931-4. doi: 10.7164/antibiotics.28.931. J Antibiot (Tokyo). 1975. PMID: 1206005
Isolation and characterization of new peptide antibiotics, plusbacins A1-A4 and B1-B4.
Shoji J, Hinoo H, Katayama T, Matsumoto K, Tanimoto T, Hattori T, Higashiyama I, Miwa H, Motokawa K, Yoshida T. Shoji J, et al. J Antibiot (Tokyo). 1992 Jun;45(6):817-23. doi: 10.7164/antibiotics.45.817. J Antibiot (Tokyo). 1992. PMID: 1500345
Synthesis and modification of a novel 1 beta-methyl carbapenem antibiotic, S-4661.
Iso Y, Irie T, Iwaki T, Kii M, Sendo Y, Motokawa K, Nishitani Y. Iso Y, et al. J Antibiot (Tokyo). 1996 May;49(5):478-84. doi: 10.7164/antibiotics.49.478. J Antibiot (Tokyo). 1996. PMID: 8682725
Orally active cephalosporins. III. Synthesis and structure-activity relationships of new 3-heterocyclicthiomethylthio-7 beta-[(Z)- 2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamido]-3-cephem-4 -carboxylic acids.
Kume M, Kubota T, Kimura Y, Nakashimizu H, Motokawa K. Kume M, et al. J Antibiot (Tokyo). 1993 Feb;46(2):316-30. doi: 10.7164/antibiotics.46.316. J Antibiot (Tokyo). 1993. PMID: 8468248
Orally active cephalosporins. II. Synthesis and structure-activity relationships of new 7 beta-[(Z)-2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamido]-cephalospori ns with 1,2,3-triazole in C-3 side chain.
Kume M, Kubota T, Kimura Y, Nakashimizu H, Motokawa K, Nakano M. Kume M, et al. J Antibiot (Tokyo). 1993 Jan;46(1):177-92. doi: 10.7164/antibiotics.46.177. J Antibiot (Tokyo). 1993. PMID: 8436551
Synthesis and structure-activity relationships of 7 beta-[(Z)-2-(2- aminothiazol-4-yl)-3-(substituted)-2-propenoyl-amino]-3- desacetoxymethylcephalosporins.
Ishikura K, Kubota T, Minami K, Hamashima Y, Nakashimizu H, Motokawa K, Yoshida T. Ishikura K, et al. J Antibiot (Tokyo). 1994 Apr;47(4):453-65. doi: 10.7164/antibiotics.47.453. J Antibiot (Tokyo). 1994. PMID: 8195046
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