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The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO.
Müller-Rischart AK, Pilsl A, Beaudette P, Patra M, Hadian K, Funke M, Peis R, Deinlein A, Schweimer C, Kuhn PH, Lichtenthaler SF, Motori E, Hrelia S, Wurst W, Trümbach D, Langer T, Krappmann D, Dittmar G, Tatzelt J, Winklhofer KF. Müller-Rischart AK, et al. Among authors: motori e. Mol Cell. 2013 Mar 7;49(5):908-21. doi: 10.1016/j.molcel.2013.01.036. Epub 2013 Feb 28. Mol Cell. 2013. PMID: 23453807 Free article.
Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels.
Mourier A, Motori E, Brandt T, Lagouge M, Atanassov I, Galinier A, Rappl G, Brodesser S, Hultenby K, Dieterich C, Larsson NG. Mourier A, et al. Among authors: motori e. J Cell Biol. 2015 Feb 16;208(4):429-42. doi: 10.1083/jcb.201411100. J Cell Biol. 2015. PMID: 25688136 Free PMC article.
Parkin cooperates with GDNF/RET signaling to prevent dopaminergic neuron degeneration.
Meka DP, Müller-Rischart AK, Nidadavolu P, Mohammadi B, Motori E, Ponna SK, Aboutalebi H, Bassal M, Annamneedi A, Finckh B, Miesbauer M, Rotermund N, Lohr C, Tatzelt J, Winklhofer KF, Kramer ER. Meka DP, et al. Among authors: motori e. J Clin Invest. 2015 May;125(5):1873-85. doi: 10.1172/JCI79300. Epub 2015 Mar 30. J Clin Invest. 2015. PMID: 25822020 Free PMC article.
27 results