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312 results
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Antigen stabilizing hydrogels based on cyclodextrins and polyethylene glycol act as type-2 adjuvants with suppressed local irritation.
Hayashi T, Nakagawa F, Ohno Y, Suzuki Y, Ishiki H, Onodera R, Higashi T, Shimamura Y, Itou H, Iwase Y, Arima H, Motoyama K. Hayashi T, et al. Among authors: motoyama k. Eur J Pharm Biopharm. 2022 Nov 10:S0939-6411(22)00253-3. doi: 10.1016/j.ejpb.2022.11.002. Online ahead of print. Eur J Pharm Biopharm. 2022. PMID: 36372270
Fine-tuned cholesterol solubilizer, mono-6-O-α-D-maltosyl-γ-cyclodextrin, ameliorates experimental Niemann-Pick disease type C without hearing loss.
Yamada Y, Miwa T, Nakashima M, Shirakawa A, Ishii A, Namba N, Kondo Y, Takeo T, Nakagata N, Motoyama K, Higashi T, Arima H, Kurauchi Y, Seki T, Katsuki H, Okada Y, Ichikawa A, Higaki K, Hayashi K, Minami K, Yoshikawa N, Ikeda R, Ishikawa Y, Kajii T, Tachii K, Takeda H, Orita Y, Matsuo M, Irie T, Ishitsuka Y. Yamada Y, et al. Among authors: motoyama k. Biomed Pharmacother. 2022 Nov;155:113698. doi: 10.1016/j.biopha.2022.113698. Epub 2022 Sep 16. Biomed Pharmacother. 2022. PMID: 36116252 Free article.
Multifunctional Therapeutic Cyclodextrin-Appended Dendrimer Complex for Treatment of Systemic and Localized Amyloidosis.
Inoue M, Higashi T, Hayashi Y, Onodera R, Fujisawa K, Taharabaru T, Yokoyama R, Ouchi K, Misumi Y, Ueda M, Inoue Y, Mizuguchi M, Saito T, Saido TC, Ando Y, Arima H, Motoyama K, Jono H. Inoue M, et al. Among authors: motoyama k. ACS Appl Mater Interfaces. 2022 Sep 14;14(36):40599-40611. doi: 10.1021/acsami.2c09913. Epub 2022 Sep 2. ACS Appl Mater Interfaces. 2022. PMID: 36052562
Lactose-Appended Hydroxypropyl-β-Cyclodextrin Lowers Cholesterol Accumulation and Alleviates Motor Dysfunction in Niemann-Pick Type C Disease Model Mice.
Nishida T, Yokoyama R, Kubohira Y, Maeda Y, Takeo T, Nakagata N, Takagi H, Ishikura K, Yanagihara K, Misumi S, Kishimoto N, Ishitsuka Y, Kondo Y, Irie T, Soga M, Era T, Onodera R, Higashi T, Motoyama K. Nishida T, et al. Among authors: motoyama k. ACS Appl Bio Mater. 2022 May 16;5(5):2377-2388. doi: 10.1021/acsabm.2c00233. Epub 2022 May 4. ACS Appl Bio Mater. 2022. PMID: 35506864
312 results