Mottis A - Search Results

1

The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling.

Mouchiroud L, Houtkooper RH, Moullan N, Katsyuba E, Ryu D, Cantó C, Mottis A, Jo YS, Viswanathan M, Schoonjans K, Guarente L, Auwerx J. Mouchiroud L, et al. Among authors: mottis a. Cell. 2013 Jul 18;154(2):430-41. doi: 10.1016/j.cell.2013.06.016. Cell. 2013. PMID: 23870130 Free PMC article.

2

Emerging roles of the corepressors NCoR1 and SMRT in homeostasis.

Mottis A, Mouchiroud L, Auwerx J. Mottis A, et al. Genes Dev. 2013 Apr 15;27(8):819-35. doi: 10.1101/gad.214023.113. Genes Dev. 2013. PMID: 23630073 Free PMC article. Review.

3

The mitochondrial unfolded protein response in mammalian physiology.

Mottis A, Jovaisaite V, Auwerx J. Mottis A, et al. Mamm Genome. 2014 Oct;25(9-10):424-33. doi: 10.1007/s00335-014-9525-z. Epub 2014 Jun 5. Mamm Genome. 2014. PMID: 24898297 Free PMC article. Review.

4

A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans.

Andreux PA, Mouchiroud L, Wang X, Jovaisaite V, Mottis A, Bichet S, Moullan N, Houtkooper RH, Auwerx J. Andreux PA, et al. Among authors: mottis a. Sci Rep. 2014 Jun 13;4:5285. doi: 10.1038/srep05285. Sci Rep. 2014. PMID: 24923838 Free PMC article.

5

SIRT2 deficiency modulates macrophage polarization and susceptibility to experimental colitis.

Lo Sasso G, Menzies KJ, Mottis A, Piersigilli A, Perino A, Yamamoto H, Schoonjans K, Auwerx J. Lo Sasso G, et al. Among authors: mottis a. PLoS One. 2014 Jul 29;9(7):e103573. doi: 10.1371/journal.pone.0103573. eCollection 2014. PLoS One. 2014. PMID: 25072851 Free PMC article.

6

Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population.

Wu Y, Williams EG, Dubuis S, Mottis A, Jovaisaite V, Houten SM, Argmann CA, Faridi P, Wolski W, Kutalik Z, Zamboni N, Auwerx J, Aebersold R. Wu Y, et al. Among authors: mottis a. Cell. 2014 Sep 11;158(6):1415-1430. doi: 10.1016/j.cell.2014.07.039. Cell. 2014. PMID: 25215496 Free PMC article.

7

Tetracyclines Disturb Mitochondrial Function across Eukaryotic Models: A Call for Caution in Biomedical Research.

Moullan N, Mouchiroud L, Wang X, Ryu D, Williams EG, Mottis A, Jovaisaite V, Frochaux MV, Quiros PM, Deplancke B, Houtkooper RH, Auwerx J. Moullan N, et al. Among authors: mottis a. Cell Rep. 2015 Mar 17;10(10):1681-1691. doi: 10.1016/j.celrep.2015.02.034. Epub 2015 Mar 12. Cell Rep. 2015. PMID: 25772356 Free PMC article.

8

Mitonuclear communication in homeostasis and stress.

Quirós PM, Mottis A, Auwerx J. Quirós PM, et al. Among authors: mottis a. Nat Rev Mol Cell Biol. 2016 Apr;17(4):213-26. doi: 10.1038/nrm.2016.23. Epub 2016 Mar 9. Nat Rev Mol Cell Biol. 2016. PMID: 26956194 Review.

9

De novo NAD⁺ synthesis enhances mitochondrial function and improves health.

Katsyuba E, Mottis A, Zietak M, De Franco F, van der Velpen V, Gariani K, Ryu D, Cialabrini L, Matilainen O, Liscio P, Giacchè N, Stokar-Regenscheit N, Legouis D, de Seigneux S, Ivanisevic J, Raffaelli N, Schoonjans K, Pellicciari R, Auwerx J. Katsyuba E, et al. Among authors: mottis a. Nature. 2018 Nov;563(7731):354-359. doi: 10.1038/s41586-018-0645-6. Epub 2018 Oct 24. Nature. 2018. PMID: 30356218 Free PMC article.

10

The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging.

D'Amico D, Mottis A, Potenza F, Sorrentino V, Li H, Romani M, Lemos V, Schoonjans K, Zamboni N, Knott G, Schneider BL, Auwerx J. D'Amico D, et al. Among authors: mottis a. Mol Cell. 2019 Feb 21;73(4):775-787.e10. doi: 10.1016/j.molcel.2018.11.034. Epub 2019 Jan 11. Mol Cell. 2019. PMID: 30642763 Free PMC article.

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