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Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis.
Hanniford D, Ulloa-Morales A, Karz A, Berzoti-Coelho MG, Moubarak RS, Sánchez-Sendra B, Kloetgen A, Davalos V, Imig J, Wu P, Vasudevaraja V, Argibay D, Lilja K, Tabaglio T, Monteagudo C, Guccione E, Tsirigos A, Osman I, Aifantis I, Hernando E. Hanniford D, et al. Among authors: moubarak rs. Cancer Cell. 2020 Jan 13;37(1):55-70.e15. doi: 10.1016/j.ccell.2019.12.007. Cancer Cell. 2020. PMID: 31935372 Free PMC article.
The histone demethylase PHF8 regulates TGFβ signaling and promotes melanoma metastasis.
Moubarak RS, de Pablos-Aragoneses A, Ortiz-Barahona V, Gong Y, Gowen M, Dolgalev I, Shadaloey SAA, Argibay D, Karz A, Von Itter R, Vega-Sáenz de Miera EC, Sokolova E, Darvishian F, Tsirigos A, Osman I, Hernando E. Moubarak RS, et al. Sci Adv. 2022 Feb 18;8(7):eabi7127. doi: 10.1126/sciadv.abi7127. Epub 2022 Feb 18. Sci Adv. 2022. PMID: 35179962 Free PMC article.
In Vivo miRNA Decoy Screen Reveals miR-124a as a Suppressor of Melanoma Metastasis.
Moubarak RS, Koetz-Ploch L, Mullokandov G, Gaziel A, de Pablos-Aragoneses A, Argibay D, Kleffman K, Sokolova E, Berwick M, Thomas NE, Osman I, Brown BD, Hernando E. Moubarak RS, et al. Front Oncol. 2022 Apr 4;12:852952. doi: 10.3389/fonc.2022.852952. eCollection 2022. Front Oncol. 2022. PMID: 35480113 Free PMC article.
FBXW7 modulates cellular stress response and metastatic potential through ​HSF1 post-translational modification.
Kourtis N, Moubarak RS, Aranda-Orgilles B, Lui K, Aydin IT, Trimarchi T, Darvishian F, Salvaggio C, Zhong J, Bhatt K, Chen EI, Celebi JT, Lazaris C, Tsirigos A, Osman I, Hernando E, Aifantis I. Kourtis N, et al. Among authors: moubarak rs. Nat Cell Biol. 2015 Mar;17(3):322-332. doi: 10.1038/ncb3121. Nat Cell Biol. 2015. PMID: 25720964 Free PMC article.
SIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L.
Coccia E, Planells-Ferrer L, Badillos-Rodríguez R, Pascual M, Segura MF, Fernández-Hernández R, López-Soriano J, Garí E, Soriano E, Barneda-Zahonero B, Moubarak RS, Pérez-García MJ, Comella JX. Coccia E, et al. Among authors: moubarak rs. Cell Death Dis. 2020 Feb 3;11(2):82. doi: 10.1038/s41419-020-2282-x. Cell Death Dis. 2020. PMID: 32015347 Free PMC article.
The long form of Fas apoptotic inhibitory molecule is expressed specifically in neurons and protects them against death receptor-triggered apoptosis.
Segura MF, Sole C, Pascual M, Moubarak RS, Perez-Garcia MJ, Gozzelino R, Iglesias V, Badiola N, Bayascas JR, Llecha N, Rodriguez-Alvarez J, Soriano E, Yuste VJ, Comella JX. Segura MF, et al. Among authors: moubarak rs. J Neurosci. 2007 Oct 17;27(42):11228-41. doi: 10.1523/JNEUROSCI.3462-07.2007. J Neurosci. 2007. PMID: 17942717 Free PMC article.
BCL-XL regulates TNF-alpha-mediated cell death independently of NF-kappaB, FLIP and IAPs.
Gozzelino R, Sole C, Llecha N, Segura MF, Moubarak RS, Iglesias-Guimarais V, Perez-Garcia MJ, Reix S, Zhang J, Badiola N, Sanchis D, Rodriguez-Alvarez J, Trullas R, Yuste VJ, Comella JX. Gozzelino R, et al. Among authors: moubarak rs. Cell Res. 2008 Oct;18(10):1020-36. doi: 10.1038/cr.2008.76. Cell Res. 2008. PMID: 18591962
30 results