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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 2
2000 3
2001 2
2002 3
2003 5
2004 6
2005 3
2006 6
2007 4
2008 4
2009 9
2010 10
2011 4
2012 3
2013 4
2014 4
2015 3
2016 7
2017 3
2018 3
2019 10
2020 6
2021 3
2022 4
2023 4
2024 3

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99 results

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Page 1
Bacterial indole-3-lactic acid affects epithelium-macrophage crosstalk to regulate intestinal homeostasis.
Yu K, Li Q, Sun X, Peng X, Tang Q, Chu H, Zhou L, Wang B, Zhou Z, Deng X, Yang J, Lv J, Liu R, Miao C, Zhao W, Yao Z, Wang Q. Yu K, et al. Proc Natl Acad Sci U S A. 2023 Nov 7;120(45):e2309032120. doi: 10.1073/pnas.2309032120. Epub 2023 Oct 30. Proc Natl Acad Sci U S A. 2023. PMID: 37903267
Here, we identified that an Escherichia coli strain (Ec-TMU) isolated from the feces of tinidazole-treated individuals, and indole-3-lactic acid (ILA) in its supernatant, decreased the susceptibility of mice to dextran sulfate sodium-induced colitis. Ec-TMU and ILA contrib …
Here, we identified that an Escherichia coli strain (Ec-TMU) isolated from the feces of tinidazole-treated individuals, and indole-3-lactic …
Fbxw7 increases CCL2/7 in CX3CR1hi macrophages to promote intestinal inflammation.
He J, Song Y, Li G, Xiao P, Liu Y, Xue Y, Cao Q, Tu X, Pan T, Jiang Z, Cao X, Lai L, Wang Q. He J, et al. J Clin Invest. 2019 Jun 27;129(9):3877-3893. doi: 10.1172/JCI123374. J Clin Invest. 2019. PMID: 31246581 Free PMC article.
In the present study, we found that increased expression of E3 ligase FBXW7 in the inflamed intestine was significantly correlated to IBD severity in both human diseases and mice model. Myeloid-Fbxw7 deficiency protected mice from dextran sodium sulfate (DSS) and 2, …
In the present study, we found that increased expression of E3 ligase FBXW7 in the inflamed intestine was significantly correlated to IBD se …
CCL27 is a crucial regulator of immune homeostasis of the skin and mucosal tissues.
Davila ML, Xu M, Huang C, Gaddes ER, Winter L, Cantorna MT, Wang Y, Xiong N. Davila ML, et al. iScience. 2022 May 18;25(6):104426. doi: 10.1016/j.isci.2022.104426. eCollection 2022 Jun 17. iScience. 2022. PMID: 35663027 Free PMC article.
Accordingly, in the skin of CCL27-knockout mice, there is a reduced presence and dysregulated localization of T cells that express CCR10, the cognate receptor to CCL27. Besides, CCL27-knockout mice have overreactive skin inflammatory responses i …
Accordingly, in the skin of CCL27-knockout mice, there is a reduced presence and dysregulated localization of T cells that exp …
Connexin26 Modulates Radiation-Induced Skin Damage by Regulating Chemokine CCL27 through MAPK Signaling.
Tao R, Mao Y, Li Y, Sun M, Cao X, Chen N, Xu S, Wang D, Zhao Y. Tao R, et al. Radiat Res. 2023 Sep 1;200(3):281-288. doi: 10.1667/RADE-20-00085.1. Radiat Res. 2023. PMID: 37450610
Proteins in the mitogen activated protein kinase (MAPK) signaling pathway and CCL27-related proteins were detected by immunoblotting. HaCaTCx26-/- cells were constructed to verify the effects of Cx26 on CCL27 secretion. A mouse model was established to examin …
Proteins in the mitogen activated protein kinase (MAPK) signaling pathway and CCL27-related proteins were detected by immunoblotting. …
CCL27/CCL28-CCR10 Chemokine Signaling Mediates Migration of Lymphatic Endothelial Cells.
Karnezis T, Farnsworth RH, Harris NC, Williams SP, Caesar C, Byrne DJ, Herle P, Macheda ML, Shayan R, Zhang YF, Yazar S, Takouridis SJ, Gerard C, Fox SB, Achen MG, Stacker SA. Karnezis T, et al. Cancer Res. 2019 Apr 1;79(7):1558-1572. doi: 10.1158/0008-5472.CAN-18-1858. Epub 2019 Feb 1. Cancer Res. 2019. PMID: 30709930
Migration assays demonstrated that LECs are attracted to both CCL27 and CCL28 in a CCR10-dependent manner, while abnormal lymphatic vessel patterning in CCR10-deficient mice confirmed the significant role of CCR10 in lymphatic patterning. ...These studies demonstrat …
Migration assays demonstrated that LECs are attracted to both CCL27 and CCL28 in a CCR10-dependent manner, while abnormal lymphatic v …
CCL27-CCR10 interactions regulate T cell-mediated skin inflammation.
Homey B, Alenius H, Müller A, Soto H, Bowman EP, Yuan W, McEvoy L, Lauerma AI, Assmann T, Bünemann E, Lehto M, Wolff H, Yen D, Marxhausen H, To W, Sedgwick J, Ruzicka T, Lehmann P, Zlotnik A. Homey B, et al. Nat Med. 2002 Feb;8(2):157-65. doi: 10.1038/nm0202-157. Nat Med. 2002. PMID: 11821900
Tumor necrosis factor-alpha and interleukin-1beta induced CCL27 production whereas the glucocorticosteroid clobetasol propionate suppressed it. ...Together, these findings indicate that CCL27-CCR10 interactions have a pivotal role in T cell-mediated skin inflammatio …
Tumor necrosis factor-alpha and interleukin-1beta induced CCL27 production whereas the glucocorticosteroid clobetasol propionate supp …
TNF family molecule LIGHT regulates chemokine CCL27 expression on mouse embryonic stem cell-derived dendritic cells through NF-kappaB activation.
Zou GM, Hu WY, Wu W. Zou GM, et al. Cell Signal. 2007 Jan;19(1):87-92. doi: 10.1016/j.cellsig.2006.05.025. Epub 2006 Jun 7. Cell Signal. 2007. PMID: 16978841
In this study, we found that esDC express CCR7 and CCR10 (the receptor of CCL27) upon the LIGHT stimulation. LIGHT also upregulates CCL27, but not CCL19 and CCL21 expression in esDC. The esDC migration potential has been increased in LIGHT activated DCs compared wit …
In this study, we found that esDC express CCR7 and CCR10 (the receptor of CCL27) upon the LIGHT stimulation. LIGHT also upregulates …
Psoriasis-associated impairment of CCL27/CCR10-derived regulation leads to IL-17A/IL-22-producing skin T-cell overactivation.
Li C, Xu M, Coyne J, Wang WB, Davila ML, Wang Y, Xiong N. Li C, et al. J Allergy Clin Immunol. 2021 Feb;147(2):759-763.e9. doi: 10.1016/j.jaci.2020.05.044. Epub 2020 Jun 10. J Allergy Clin Immunol. 2021. PMID: 32533971 Free PMC article.
Psoriasis-associated suppression of the skin-specific chemokine/receptor CCL27/CCR10 axis leads to enhanced pathogenic IL-17A/IL-22-producing skin T cell activation and inflammation....
Psoriasis-associated suppression of the skin-specific chemokine/receptor CCL27/CCR10 axis leads to enhanced pathogenic IL-17A/IL-22-p …
Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584.
Singh P, Aulakh GK. Singh P, et al. Front Immunol. 2023 Mar 13;14:1126574. doi: 10.3389/fimmu.2023.1126574. eCollection 2023. Front Immunol. 2023. PMID: 36993977 Free PMC article.
We modeled acute lung inflammation (ALI) by exposing 6-8 week old male mice to 0.005 ppm ozone for 2 h followed by 50 mug of intranasal LPS. ...Ozone and LPS exposure induced lung neutrophil and eosinophil recruitment as measured by respective peroxidase (MPO and EPX) assa …
We modeled acute lung inflammation (ALI) by exposing 6-8 week old male mice to 0.005 ppm ozone for 2 h followed by 50 mug of intranas …
Large chemokine binding spectrum of human and mouse atypical chemokine receptor GPR182 (ACKR5).
Bonnavion R, Liu S, Kawase H, Roquid KA, Offermanns S. Bonnavion R, et al. Front Pharmacol. 2023 Nov 1;14:1297596. doi: 10.3389/fphar.2023.1297596. eCollection 2023. Front Pharmacol. 2023. PMID: 38026988 Free PMC article.
Here, we comprehensively investigated the chemokine binding profile of human and mouse GPR182. Competitive binding assays using flow cytometry revealed that besides CXCL10, CXCL12 and CXCL13, also human and mouse CXCL11, CXCL14 and CCL25, as well as human CCL1, CCL1 …
Here, we comprehensively investigated the chemokine binding profile of human and mouse GPR182. Competitive binding assays using flow …
99 results