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Expression and function of the interleukin 7 receptor in murine lymphocytes.
Sudo T, Nishikawa S, Ohno N, Akiyama N, Tamakoshi M, Yoshida H, Nishikawa S. Sudo T, et al. Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):9125-9. doi: 10.1073/pnas.90.19.9125. Proc Natl Acad Sci U S A. 1993. PMID: 8415665 Free PMC article.
A monoclonal antibody, A7R34, that recognizes the high-affinity interleukin 7 receptor (IL-7Ra) and blocks the binding between IL-7 and IL-7Ra has been produced. ...When A7R34 injection is started from day 14 of gestation, it is possible to produce …
A monoclonal antibody, A7R34, that recognizes the high-affinity interleukin 7 receptor (IL-7Ra) and blocks the binding …
Blockade of Interleukin-7 Receptor Shapes Macrophage Alternative Activation and Promotes Functional Recovery After Spinal Cord Injury.
Bao C, Wang B, Yang F, Chen L. Bao C, et al. Neuroscience. 2018 Feb 10;371:518-527. doi: 10.1016/j.neuroscience.2017.10.022. Epub 2017 Oct 22. Neuroscience. 2018. PMID: 29069618
Furthermore, IL-7 displays strong chemotactic property for macrophages and A7R34 treatment inhibits their infiltration into injured sites in vivo. More importantly, the A7R34 treatment promotes functional recovery after SCI, indicating its therapeutic effects on spi …
Furthermore, IL-7 displays strong chemotactic property for macrophages and A7R34 treatment inhibits their infiltration into injured s …
A critical role for IL-7R signaling in the development of Helicobacter felis-induced gastritis in mice.
Ohana M, Okazaki K, Oshima C, Andra's D, Nishi T, Uchida K, Uose S, Nakase H, Matsushima Y, Chiba T. Ohana M, et al. Gastroenterology. 2001 Aug;121(2):329-36. doi: 10.1053/gast.2001.26289. Gastroenterology. 2001. PMID: 11487542
Histology, serum anti-H. felis antibody, and gene expression of IL-7, IL-7R, and proinflammatory cytokines in the gastric mucosa were evaluated. RESULTS: Seventeen of 20 (85%) infected mice without A7R34 developed severe atrophic gastritis, whereas there was no gast …
Histology, serum anti-H. felis antibody, and gene expression of IL-7, IL-7R, and proinflammatory cytokines in the gastric mucosa were evalua …