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The following term was not found in PubMed: R7129.7
Page 1
CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder.
Wang X, Liu M, Zhang J, Brown NK, Zhang P, Zhang Y, Liu H, Du X, Wu W, Devenport M, Tao W, Mao-Draayer Y, Chen GY, Chen YE, Zheng P, Liu Y. Wang X, et al. Cell Metab. 2022 Aug 2;34(8):1088-1103.e6. doi: 10.1016/j.cmet.2022.07.005. Cell Metab. 2022. PMID: 35921817 Free PMC article.
The molecular interactions that regulate chronic inflammation underlying metabolic disease remain largely unknown. Since the CD24-Siglec interaction regulates inflammatory response to danger-associated molecular patterns (DAMPs), we have generated multiple mouse str …
The molecular interactions that regulate chronic inflammation underlying metabolic disease remain largely unknown. Since the CD24-Sig …
The epithelial-mesenchymal transition generates cells with properties of stem cells.
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, Yang J, Weinberg RA. Mani SA, et al. Cell. 2008 May 16;133(4):704-15. doi: 10.1016/j.cell.2008.03.027. Cell. 2008. PMID: 18485877 Free PMC article.
Independent of this, stem cell-like cells isolated from HMLE cultures form mammospheres and express markers similar to those of HMLEs that have undergone an EMT. Moreover, stem-like cells isolated either from mouse or human mammary glands or mammary carcinomas express EMT …
Independent of this, stem cell-like cells isolated from HMLE cultures form mammospheres and express markers similar to those of HMLEs that h …
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts.
Sato T, van Es JH, Snippert HJ, Stange DE, Vries RG, van den Born M, Barker N, Shroyer NF, van de Wetering M, Clevers H. Sato T, et al. Nature. 2011 Jan 20;469(7330):415-8. doi: 10.1038/nature09637. Epub 2010 Nov 28. Nature. 2011. PMID: 21113151 Free PMC article.
Here we find a close physical association of Lgr5 stem cells with Paneth cells in mice, both in vivo and in vitro. CD24(+) Paneth cells express EGF, TGF-alpha, Wnt3 and the Notch ligand Dll4, all essential signals for stem-cell maintenance in culture. ...Genetic rem …
Here we find a close physical association of Lgr5 stem cells with Paneth cells in mice, both in vivo and in vitro. CD24(+) Pan …
CD24 and Siglec-10 selectively repress tissue damage-induced immune responses.
Chen GY, Tang J, Zheng P, Liu Y. Chen GY, et al. Science. 2009 Mar 27;323(5922):1722-5. doi: 10.1126/science.1168988. Epub 2009 Mar 5. Science. 2009. PMID: 19264983 Free PMC article.
Whether and how the host distinguishes between danger- versus pathogen-associated molecular patterns remains unresolved. We report that CD24-deficient mice exhibit increased susceptibility to danger- but not pathogen-associated molecular patterns. ...This occurs at …
Whether and how the host distinguishes between danger- versus pathogen-associated molecular patterns remains unresolved. We report that C …
Nano-LYTACs for Degradation of Membrane Proteins and Inhibition of CD24/Siglec-10 Signaling Pathway.
Wang K, Yu A, Liu K, Feng C, Hou Y, Chen J, Ma S, Huang L, Dai X. Wang K, et al. Adv Sci (Weinh). 2023 May;10(13):e2300288. doi: 10.1002/advs.202300288. Epub 2023 Mar 3. Adv Sci (Weinh). 2023. PMID: 36866919 Free PMC article.
They can degrade different membranes and extracellular proteins by linking with the relevant antibodies. CD24, a heavily glycosylated glycosylphosphatidylinositol-anchored surface protein, interacts with Siglec-10 to modulate the tumor immune response. The novel Nanosphere …
They can degrade different membranes and extracellular proteins by linking with the relevant antibodies. CD24, a heavily glycosylated …
Senescent cells suppress macrophage-mediated corpse removal via upregulation of the CD47-QPCT/L axis.
Schloesser D, Lindenthal L, Sauer J, Chung KJ, Chavakis T, Griesser E, Baskaran P, Maier-Habelsberger U, Fundel-Clemens K, Schlotthauer I, Watson CK, Swee LK, Igney F, Park JE, Huber-Lang MS, Thomas MJ, El Kasmi KC, Murray PJ. Schloesser D, et al. J Cell Biol. 2023 Feb 6;222(2):e202207097. doi: 10.1083/jcb.202207097. Epub 2022 Dec 2. J Cell Biol. 2023. PMID: 36459066 Free PMC article.
SCES was reversible by interfering with the SIRPalpha-CD47-SHP-1 axis or QPCT/L activity. While CD47 expression increased in human and mouse senescent cells in vitro and in vivo, another ITIM-containing protein, CD24, contributed to SCES specifically in human epithe …
SCES was reversible by interfering with the SIRPalpha-CD47-SHP-1 axis or QPCT/L activity. While CD47 expression increased in human and mo …
Identification and Characterization of Tumor-Initiating Cells in Multiple Myeloma.
Gao M, Bai H, Jethava Y, Wu Y, Zhu Y, Yang Y, Xia J, Cao H, Franqui-Machin R, Nadiminti K, Thomas GS, Salama ME, Altevogt P, Bishop G, Tomasson M, Janz S, Shi J, Chen L, Frech I, Tricot G, Zhan F. Gao M, et al. J Natl Cancer Inst. 2020 May 1;112(5):507-515. doi: 10.1093/jnci/djz159. J Natl Cancer Inst. 2020. PMID: 31406992 Free PMC article.
Therapeutic effects of CD24 antibodies were tested in xenograft MM mouse models containing three to six mice per group. ...Only 10 CD24+ MM cells were required to develop plasmacytomas in mice (n = three of five mice after 27 days). ...
Therapeutic effects of CD24 antibodies were tested in xenograft MM mouse models containing three to six mice per group. …
CD24 tracks divergent pluripotent states in mouse and human cells.
Shakiba N, White CA, Lipsitz YY, Yachie-Kinoshita A, Tonge PD, Hussein SMI, Puri MC, Elbaz J, Morrissey-Scoot J, Li M, Munoz J, Benevento M, Rogers IM, Hanna JH, Heck AJR, Wollscheid B, Nagy A, Zandstra PW. Shakiba N, et al. Nat Commun. 2015 Jun 16;6:7329. doi: 10.1038/ncomms8329. Nat Commun. 2015. PMID: 26076835 Free PMC article.
Furthermore, CD24 can be used to delineate epiblast stem cells (EpiSCs) from embryonic stem cells (ESCs) in mouse pluripotent culture. ...Thus, CD24 is a conserved marker for tracking divergent states in both reprogramming and standard pluripotent culture....
Furthermore, CD24 can be used to delineate epiblast stem cells (EpiSCs) from embryonic stem cells (ESCs) in mouse pluripotent …
O-glycosylation pattern of CD24 from mouse brain.
Bleckmann C, Geyer H, Lieberoth A, Splittstoesser F, Liu Y, Feizi T, Schachner M, Kleene R, Reinhold V, Geyer R. Bleckmann C, et al. Biol Chem. 2009 Jul;390(7):627-45. doi: 10.1515/BC.2009.044. Biol Chem. 2009. PMID: 19284289
Since CD24 comprises only a short protein core of approximately 30 amino acids and low conservation among species, it has been proposed that the functions of CD24 are mediated by its glycosylation pattern. ...Furthermore, de-N-glycosylated CD24 was shown to p …
Since CD24 comprises only a short protein core of approximately 30 amino acids and low conservation among species, it has been propos …
Inhaled CD24-Enriched Exosomes (EXO-CD24) as a Novel Immune Modulator in Respiratory Disease.
Shapira S, Schwartz R, Tsiodras S, Bar-Shai A, Melloul A, Borsekofsky S, Peer M, Adi N, MacLoughlin R, Arber N. Shapira S, et al. Int J Mol Sci. 2023 Dec 20;25(1):77. doi: 10.3390/ijms25010077. Int J Mol Sci. 2023. PMID: 38203250 Free PMC article.
CD24 allows for immune discrimination between Damage-Associated Molecular Patterns and Pathogen-Associated Molecular Patterns derived from pathogens. ...EXO CD24 can suppress the hyperinflammatory response in the lungs in several pulmonary diseases with a significan …
CD24 allows for immune discrimination between Damage-Associated Molecular Patterns and Pathogen-Associated Molecular Patterns derived …
1,445 results