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Year Number of Results
1990 2
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1994 10
1995 8
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62 results

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Page 1
Functional analysis of Mel-14+ and Mel-14- early precursor cells in the adult mouse thymus.
Wu L, D'Amico A. Wu L, et al. Immunol Lett. 1994 May;40(2):89-92. doi: 10.1016/0165-2478(94)90177-5. Immunol Lett. 1994. PMID: 7522220
The earliest T-cell precursor population in the adult mouse thymus (low CD4 precursors) may be divided into 85% of cells expressing surface Mel-14 (LECAM-1, the lymphocyte homing receptor) and 15% of cells which are Mel-14. To date, this is the …
The earliest T-cell precursor population in the adult mouse thymus (low CD4 precursors) may be divided into 85% of cells expressing s …
Functional studies on MEL-14+ and MEL-14- T cells in peripheral lymphoid tissues.
Ohgama J, Katoh M, Hirano M, Arase H, Arase-Fukushi N, Mishima M, Iwabuchi K, Ogasawara K, Onoé K. Ohgama J, et al. Immunobiology. 1994 Apr;190(3):225-42. doi: 10.1016/S0171-2985(11)80271-8. Immunobiology. 1994. PMID: 7522213
Functions of MEL-14+ T cells and MEL-14- T cells in peripheral lymphoid tissues were analyzed and compared. ...Furthermore, upon stimulation with ConA the MEL-14- CD8+ T cells produced significantly larger amounts of IL-2 and IFN-gamma th …
Functions of MEL-14+ T cells and MEL-14- T cells in peripheral lymphoid tissues were analyzed and compared. ...F …
Multiple roles of Leu-8/MEL-14 in leukocyte adhesion and function.
James SP, Murakawa Y, Kanof ME, Berg M. James SP, et al. Immunol Res. 1991;10(3-4):282-92. doi: 10.1007/BF02919708. Immunol Res. 1991. PMID: 1720159 Review.
Leu-8 and its murine homologue MEL-14 are members of a new family of adhesion molecules encoded on chromosome-1 that share common structural features, including lectin-like domains and tandem repeats homologous to complement binding proteins. The expression of Leu-8 …
Leu-8 and its murine homologue MEL-14 are members of a new family of adhesion molecules encoded on chromosome-1 that share com …
The age-associated increase in IFN-gamma synthesis by mouse CD8+ T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expression.
Ernst DN, Weigle WO, Noonan DJ, McQuitty DN, Hobbs MV. Ernst DN, et al. J Immunol. 1993 Jul 15;151(2):575-87. J Immunol. 1993. PMID: 7687616
Immunophenotypic analyses of membrane CD44, CD45RB, 3G11, and MEL-14 expression by splenic CD8+ cells from young-adult, intermediate-aged, and old mice revealed an age-associated decrease in the frequencies of cells that expressed low levels of CD44 and high …
Immunophenotypic analyses of membrane CD44, CD45RB, 3G11, and MEL-14 expression by splenic CD8+ cells from young-adult, interm …
Homing receptors reexamined: mouse LECAM-1 (MEL-14 antigen) is involved in lymphocyte migration into gut-associated lymphoid tissue.
Hamann A, Jablonski-Westrich D, Jonas P, Thiele HG. Hamann A, et al. Eur J Immunol. 1991 Dec;21(12):2925-9. doi: 10.1002/eji.1830211205. Eur J Immunol. 1991. PMID: 1721022
Here we present evidence that in vivo the molecule is also implicated in homing of mouse lymphocytes to Peyer's patches and may have a more general role as homing receptor for high endothelial venules-bearing lymphoid tissue, but not for most non-lymphoid tissue....
Here we present evidence that in vivo the molecule is also implicated in homing of mouse lymphocytes to Peyer's patches and may have …
Enrichment for Th1 cells in the Mel-14+ CD4+ T cell fraction in aged mice.
Dobber R, Tielemans M, Nagelkerken L. Dobber R, et al. Cell Immunol. 1995 May;162(2):321-5. doi: 10.1006/cimm.1995.1085. Cell Immunol. 1995. PMID: 7538051
CD4+ T cells from young and aged mice were sorted into Mel-14+ cells which are regarded as naive cells and Mel-14- cells which are regarded as memory cells. ...Mel-14+ cells from young mice only secrete substantial amounts o …
CD4+ T cells from young and aged mice were sorted into Mel-14+ cells which are regarded as naive cells and Mel- …
Recirculation, phenotype and functions of lymphocytes in mice treated with monoclonal antibody MEL-14.
Lepault F, Gagnerault MC, Faveeuw C, Boitard C. Lepault F, et al. Eur J Immunol. 1994 Dec;24(12):3106-12. doi: 10.1002/eji.1830241229. Eur J Immunol. 1994. PMID: 7528669
Here we demonstrate that in vivo a single injection of MEL-14 antibody induces a rapid, almost complete and reversible down-regulation of L-selectin expression on both T and B cells. ...MEL-14 treatment induces profound alterations of cel …
Here we demonstrate that in vivo a single injection of MEL-14 antibody induces a rapid, almost complete and reversible down-re …
Quantitative and qualitative changes in CD44 and MEL-14 expression by T cells in C57BL/6 mice during aging.
Barrat F, Haegel H, Louise A, Vincent-Naulleau S, Boulouis HJ, Neway T, Ceredig R, Pilet C. Barrat F, et al. Res Immunol. 1995 Jan;146(1):23-34. doi: 10.1016/0923-2494(96)80237-9. Res Immunol. 1995. PMID: 7569310
Aging is associated with a decrease in the functional activity of T cells. We have explored age-related alterations in CD44 and MEL-14 expression by spleen cells bearing the Thy1.2, CD4 or CD8 antigens in C57BL/6 mice at 2, 8, 15 and 23 months of age. ...In o …
Aging is associated with a decrease in the functional activity of T cells. We have explored age-related alterations in CD44 and MEL- …
Entry of naive CD4 T cells into peripheral lymph nodes requires L-selectin.
Bradley LM, Watson SR, Swain SL. Bradley LM, et al. J Exp Med. 1994 Dec 1;180(6):2401-6. doi: 10.1084/jem.180.6.2401. J Exp Med. 1994. PMID: 7525854 Free PMC article.
Previous studies have shown that treatment of lymphocytes with antibody to L-selectin (MEL-14) ablates trafficking to peripheral lymph nodes (PLN). In mice, naive but not memory CD4 cells express L-selectin. To examine the role of …
Previous studies have shown that treatment of lymphocytes with antibody to L-selectin (MEL-14) ablates trafficki …
The development of natural killer (NK) cells from Thy-1loLin-Sca-1+ stem cells: acquisition by NK cells in vivo of the homing receptor MEL-14 and the integrin Mac-1.
Miller SC. Miller SC. Immunobiology. 1994 Jun;190(4-5):385-98. doi: 10.1016/S0171-2985(11)80610-8. Immunobiology. 1994. PMID: 7527011
At the same intervals, moreover, the proportions of NK 1.1+ lymphoid cells bearing either the homing receptor recognized by mAb MEL-14, or the integrin Mac-1 were recorded using double immunofluorescence microscopy, labelling variously with fluorescein isothiocynate …
At the same intervals, moreover, the proportions of NK 1.1+ lymphoid cells bearing either the homing receptor recognized by mAb MEL- …
62 results