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The following term was not found in PubMed: 114.8.1
Page 1
Did you mean mouse the 114.8.1 (2,309,633 results)?
Tetrahydroberberine Prevents Ovariectomy-Induced Bone Loss by Inhibiting RANKL-Induced Osteoclastogenesis and Promoting Osteoclast Apoptosis.
Wu Q, Liang H, Wang C, Chen Y, Yu C, Luo J, Cai L, Miao J, Xu J, Jin H, Wang X. Wu Q, et al. J Agric Food Chem. 2024 Sep 18;72(37):20383-20395. doi: 10.1021/acs.jafc.4c02982. Epub 2024 Sep 5. J Agric Food Chem. 2024. PMID: 39238071
However, the impact of THB on PMOP has not been systematically explored. In vitro experiments supported that THB suppresses osteoclast formation and resorption of bone concentration-dependently. ...In conclusion, THB has such potential to improve the PMOP sta …
However, the impact of THB on PMOP has not been systematically explored. In vitro experiments supported that THB suppresses os …
Discovery of THB Derivates as Ferroptosis Inhibitors for the Treatment of Acute Kidney Injury by Targeting VDAC.
Peng S, Zhang W, Sun Q, Zhang W, Chen Y, Lv Z, Fang Z, Wei X, Lu T, Chen G, Jiao Y. Peng S, et al. J Med Chem. 2025 Jun 12;68(11):11340-11364. doi: 10.1021/acs.jmedchem.5c00280. Epub 2025 May 22. J Med Chem. 2025. PMID: 40402184
Through structural optimization, a series of THB derivatives were developed, among which 34a exhibited about 100-fold enhanced ferroptosis inhibitory activity. ...These results highlight the potential of 12-amino THB derivatives as novel ferroptosis inhibitors and p …
Through structural optimization, a series of THB derivatives were developed, among which 34a exhibited about 100-fold enhanced ferrop …
The human E48 antigen, highly homologous to the murine Ly-6 antigen ThB, is a GPI-anchored molecule apparently involved in keratinocyte cell-cell adhesion.
Brakenhoff RH, Gerretsen M, Knippels EM, van Dijk M, van Essen H, Weghuis DO, Sinke RJ, Snow GB, van Dongen GA. Brakenhoff RH, et al. J Cell Biol. 1995 Jun;129(6):1677-89. doi: 10.1083/jcb.129.6.1677. J Cell Biol. 1995. PMID: 7790363 Free PMC article.
The expression of the gene is confined to keratinocytes and squamous tumor cells. The putative mouse homologue, the ThB antigen, originally identified as an antigen on cells of the lymphocyte lineage, was shown to be highly expressed in squamous mouse epithel …
The expression of the gene is confined to keratinocytes and squamous tumor cells. The putative mouse homologue, the ThB antige …
A GSH-consuming polymeric nanoparticles drives ferroptosis amplification and combines chemotherapy to amplify breast cancer treatment.
Pei M, Guan X, Hou X, Niu Z, Lyu Q, Wang K, Wang S, Zhang J, Ke Y, Zhuang S, Chen J, Xu H, Yang F. Pei M, et al. J Nanobiotechnology. 2025 Jul 9;23(1):497. doi: 10.1186/s12951-025-03569-7. J Nanobiotechnology. 2025. PMID: 40634983 Free PMC article.
Here, this document highlighted polymeric nanoparticles with GSH resection (ssP-tHB@Fe/DOX), demonstrating significant improvements in TME responses, biocompatibility, and anti-tumor effects. ...Moreover, RNA sequencing (RNA-seq) analysis robustly supported the anti-tumor …
Here, this document highlighted polymeric nanoparticles with GSH resection (ssP-tHB@Fe/DOX), demonstrating significant improvements i …
Monoclonal antibodies to ThB detect close linkage of Ly-6 and a gene regulating ThB expression.
Eckhardt LA, Herzenberg LA. Eckhardt LA, et al. Immunogenetics. 1980;11(3):275-91. doi: 10.1007/BF01567794. Immunogenetics. 1980. PMID: 6793507
While the latter four antigens were described as markers on mature T (or activated T and B) lymphocytes, ThB is restricted to immature thymocytes and all B cells. ThB is not expressed on kidney, although some investigators (McKenzie et al. 1977 a, Halloran et al. 19 …
While the latter four antigens were described as markers on mature T (or activated T and B) lymphocytes, ThB is restricted to immatur …
Identification of a surface protein (p100) associated with two glycosyl-phosphatidylinositol-linked molecules (Thy-1 and ThB) by natural anti-lymphocyte autoantibodies.
Lehuen A, Monteiro RC, Kearney JF. Lehuen A, et al. Eur J Immunol. 1992 Sep;22(9):2373-80. doi: 10.1002/eji.1830220929. Eur J Immunol. 1992. PMID: 1355432
Our previous study of natural autoantibodies showed that anti-lymphocyte antibodies are frequently produced by perinatal B cells from normal strains of mice. One-third of these monoclonal antibodies (mAb) recognized similar epitopes on the surface of thymocytes. ...Inhibit …
Our previous study of natural autoantibodies showed that anti-lymphocyte antibodies are frequently produced by perinatal B cells from normal …
Activation of the Nrf2 Signaling Pathway by Tetrahydroberberine Suppresses Ferroptosis and Enhances Functional Recovery Following Spinal Cord Injury.
Li X, Yu H, Liu R, Miao J, Lv J, Yang S, Zhu Y, Chen Y, Lu K, Huang C, Wang X. Li X, et al. Mol Neurobiol. 2025 Jul;62(7):8439-8456. doi: 10.1007/s12035-025-04791-y. Epub 2025 Feb 26. Mol Neurobiol. 2025. PMID: 40011360
THB markedly improved tissue and motor function restoration in mice post-SCI, with the BMS score increasing by approximately 50% compared with that in the control group. Lipid peroxidation assays revealed that THB significantly reduced MDA levels and increase …
THB markedly improved tissue and motor function restoration in mice post-SCI, with the BMS score increasing by approximately 5 …
Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse.
Lewis L, Borowa-Mazgaj B, de Conti A, Chappell GA, Luo YS, Bodnar W, Konganti K, Wright FA, Threadgill DW, Chiu WA, Pogribny IP, Rusyn I. Lewis L, et al. Chem Res Toxicol. 2019 May 20;32(5):887-898. doi: 10.1021/acs.chemrestox.9b00035. Epub 2019 Apr 25. Chem Res Toxicol. 2019. PMID: 30990016 Free PMC article.
This study aimed to investigate interindividual variability in the effects of 1,3-butadiene using a population-based mouse model. Male mice from 20 Collaborative Cross strains were exposed to 0 or 635 ppm 1,3-butadiene by inhalation (6 h/day, 5 days/week) for 2 week …
This study aimed to investigate interindividual variability in the effects of 1,3-butadiene using a population-based mouse model. Mal …
[Behavioral pharmacology of berberine-type alkaloids. (2) Central depressant effects of tetrahydroberberine (THB) and related compounds].
Yamahara J. Yamahara J. Nihon Yakurigaku Zasshi. 1976 Oct;72(7):909-27. Nihon Yakurigaku Zasshi. 1976. PMID: 1035192 Japanese.
The behavioral effects of tetrahydroberberine (THB), tetrahydrocoptisine (THC), tetrahydropalmatine (THP) and tetrahydrojateorrhizine (THJ) were compared with those of chlorpromazine (CPZ) and benzodiazepines in mice and rats. ...The acute toxicity of THB was …
The behavioral effects of tetrahydroberberine (THB), tetrahydrocoptisine (THC), tetrahydropalmatine (THP) and tetrahydrojateorrhizine …
CAR T-cells targeting CD117 effectively eliminate mast cells in preclinical models of advanced systemic mastocytosis.
Kaiser A, Lysenko V, Myburgh R, Volta L, Pellegrino C, Theocharides APA, Christen D, Panse J, Bühler MM, Arock M, Butterfield J, de Toledo MAS, Valent P, Zenke M, Brümmendorf TH, Manz MG. Kaiser A, et al. Leukemia. 2026 Jul;40(7):1482-1493. doi: 10.1038/s41375-026-02968-5. Epub 2026 May 7. Leukemia. 2026. PMID: 42098408 Free PMC article.
In vitro, anti-CD117-CAR T-cells efficiently lysed several SM-related human MC cell lines, MCs differentiated from SM patient-derived induced pluripotent stem (iPS) cells, and neoplastic bone marrow cells obtained from SM patients. Furthermore, in immunocompromised mice en …
In vitro, anti-CD117-CAR T-cells efficiently lysed several SM-related human MC cell lines, MCs differentiated from SM patient-derived induce …
134 results