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Page 1
A-kinase anchoring proteins as potential drug targets.
Tröger J, Moutty MC, Skroblin P, Klussmann E. Tröger J, et al. Among authors: moutty mc. Br J Pharmacol. 2012 May;166(2):420-33. doi: 10.1111/j.1476-5381.2011.01796.x. Br J Pharmacol. 2012. PMID: 22122509 Free PMC article. Review.
The A-Kinase Anchoring Protein (AKAP) Glycogen Synthase Kinase 3β Interaction Protein (GSKIP) Regulates β-Catenin through Its Interactions with Both Protein Kinase A (PKA) and GSK3β.
Dema A, Schröter MF, Perets E, Skroblin P, Moutty MC, Deàk VA, Birchmeier W, Klussmann E. Dema A, et al. Among authors: moutty mc. J Biol Chem. 2016 Sep 9;291(37):19618-30. doi: 10.1074/jbc.M116.738047. Epub 2016 Aug 2. J Biol Chem. 2016. PMID: 27484798 Free PMC article.
Highly functionalized terpyridines as competitive inhibitors of AKAP-PKA interactions.
Schäfer G, Milić J, Eldahshan A, Götz F, Zühlke K, Schillinger C, Kreuchwig A, Elkins JM, Abdul Azeez KR, Oder A, Moutty MC, Masada N, Beerbaum M, Schlegel B, Niquet S, Schmieder P, Krause G, von Kries JP, Cooper DM, Knapp S, Rademann J, Rosenthal W, Klussmann E. Schäfer G, et al. Among authors: moutty mc. Angew Chem Int Ed Engl. 2013 Nov 11;52(46):12187-91. doi: 10.1002/anie.201304686. Epub 2013 Sep 23. Angew Chem Int Ed Engl. 2013. PMID: 24115519 Free PMC article. No abstract available.
Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes.
Christian F, Szaszák M, Friedl S, Drewianka S, Lorenz D, Goncalves A, Furkert J, Vargas C, Schmieder P, Götz F, Zühlke K, Moutty M, Göttert H, Joshi M, Reif B, Haase H, Morano I, Grossmann S, Klukovits A, Verli J, Gáspár R, Noack C, Bergmann M, Kass R, Hampel K, Kashin D, Genieser HG, Herberg FW, Willoughby D, Cooper DM, Baillie GS, Houslay MD, von Kries JP, Zimmermann B, Rosenthal W, Klussmann E. Christian F, et al. J Biol Chem. 2011 Mar 18;286(11):9079-96. doi: 10.1074/jbc.M110.160614. Epub 2010 Dec 22. J Biol Chem. 2011. PMID: 21177871 Free PMC article.
AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR.
Carlson CR, Aronsen JM, Bergan-Dahl A, Moutty MC, Lunde M, Lunde PK, Jarstadmarken H, Wanichawan P, Pereira L, Kolstad TRS, Dalhus B, Subramanian H, Hille S, Christensen G, Müller OJ, Nikolaev V, Bers DM, Sjaastad I, Shen X, Louch WE, Klussmann E, Sejersted OM. Carlson CR, et al. Among authors: moutty mc. Circ Res. 2022 Jan 7;130(1):27-44. doi: 10.1161/CIRCRESAHA.120.317976. Epub 2021 Nov 24. Circ Res. 2022. PMID: 34814703 Free PMC article.
Small-molecule screening identifies modulators of aquaporin-2 trafficking.
Bogum J, Faust D, Zühlke K, Eichhorst J, Moutty MC, Furkert J, Eldahshan A, Neuenschwander M, von Kries JP, Wiesner B, Trimpert C, Deen PM, Valenti G, Rosenthal W, Klussmann E. Bogum J, et al. Among authors: moutty mc. J Am Soc Nephrol. 2013 Apr;24(5):744-58. doi: 10.1681/ASN.2012030295. Epub 2013 Apr 4. J Am Soc Nephrol. 2013. PMID: 23559583 Free PMC article.
A novel calmodulin-Ca2+ target recognition activates the Bcl-2 regulator FKBP38.
Edlich F, Maestre-Martínez M, Jarczowski F, Weiwad M, Moutty MC, Malesević M, Jahreis G, Fischer G, Lücke C. Edlich F, et al. Among authors: moutty mc. J Biol Chem. 2007 Dec 14;282(50):36496-504. doi: 10.1074/jbc.M705061200. Epub 2007 Oct 17. J Biol Chem. 2007. PMID: 17942410 Free article.
The Bcl-2 regulator FKBP38-calmodulin-Ca2+ is inhibited by Hsp90.
Edlich F, Erdmann F, Jarczowski F, Moutty MC, Weiwad M, Fischer G. Edlich F, et al. Among authors: moutty mc. J Biol Chem. 2007 May 25;282(21):15341-8. doi: 10.1074/jbc.M611594200. Epub 2007 Mar 22. J Biol Chem. 2007. PMID: 17379601 Free article.
12 results