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Movements of exploration intact in rats with hippocampal lesions.
Clark BJ, Hines DJ, Hamilton DA, Whishaw IQ. Clark BJ, et al. Behav Brain Res. 2005 Aug 30;163(1):91-9. doi: 10.1016/j.bbr.2005.04.007. Behav Brain Res. 2005. PMID: 15904983
Prompted by the theoretical prediction that damage to the hippocampus should abolish exploratory behavior, the present study examined exploratory movements in control rats and rats with hippocampal lesions produced with the neurotoxin N-m …
Prompted by the theoretical prediction that damage to the hippocampus should abolish exploratory behavior, the present study examined …
En route to delineating hippocampal roles in spatial learning.
Poulter S, Austen JM, Kosaki Y, Dachtler J, Lever C, McGregor A. Poulter S, et al. Behav Brain Res. 2019 Sep 2;369:111936. doi: 10.1016/j.bbr.2019.111936. Epub 2019 May 2. Behav Brain Res. 2019. PMID: 31055057
However, when rats were either given hippocampal lesions, or placed in a light-tight box during transportation to the hidden goal, passive-placement spatial learning was facilitated. ...Finally, demonstrating that our lesions were sufficiently deleteri …
However, when rats were either given hippocampal lesions, or placed in a light-tight box during transportation to the h …
Head direction cells in rats with hippocampal or overlying neocortical lesions: evidence for impaired angular path integration.
Golob EJ, Taube JS. Golob EJ, et al. J Neurosci. 1999 Aug 15;19(16):7198-211. doi: 10.1523/JNEUROSCI.19-16-07198.1999. J Neurosci. 1999. PMID: 10436073 Free PMC article.
HD cells from both lesion groups were unable to maintain a similar preferred direction between environments, with cells from hippocampal rats showing larger shifts than cells from rats sustaining only cortical damage. When the rats first expl
HD cells from both lesion groups were unable to maintain a similar preferred direction between environments, with cells from hippo
The effects of excitotoxic lesion of the medial prefrontal cortex on latent inhibition, prepulse inhibition, food hoarding, elevated plus maze, active avoidance and locomotor activity in the rat.
Lacroix L, Broersen LM, Weiner I, Feldon J. Lacroix L, et al. Neuroscience. 1998 May;84(2):431-42. doi: 10.1016/s0306-4522(97)00521-6. Neuroscience. 1998. PMID: 9539214
Prepulse inhibition, exploration of the elevated plus maze, and the acquisition of two-way active avoidance were unaffected by the lesion. Likewise, latent inhibition was left intact following the lesion, suggesting that neither the destruction of the …
Prepulse inhibition, exploration of the elevated plus maze, and the acquisition of two-way active avoidance were unaffected by the …
Reactivity to object and spatial novelty is normal in older Ts65Dn mice that model Down syndrome and Alzheimer's disease.
Hyde LA, Crnic LS. Hyde LA, et al. Brain Res. 2002 Jul 26;945(1):26-30. doi: 10.1016/s0006-8993(02)02500-3. Brain Res. 2002. PMID: 12113948
Ts65Dn mice, a model for Down syndrome and Alzheimer's disease, have a spontaneous age-related reduction of cholinergic markers in medial septal neurons, hippocampal abnormalities, and an age-related learning deficit in a task that requires an intact hippocam …
Ts65Dn mice, a model for Down syndrome and Alzheimer's disease, have a spontaneous age-related reduction of cholinergic markers in me …