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Page 1
Drug Discovery for Kinetoplastid Diseases: Future Directions.
Rao SPS, Barrett MP, Dranoff G, Faraday CJ, Gimpelewicz CR, Hailu A, Jones CL, Kelly JM, Lazdins-Helds JK, Mäser P, Mengel J, Mottram JC, Mowbray CE, Sacks DL, Scott P, Späth GF, Tarleton RL, Spector JM, Diagana TT. Rao SPS, et al. Among authors: mowbray ce. ACS Infect Dis. 2019 Feb 8;5(2):152-157. doi: 10.1021/acsinfecdis.8b00298. Epub 2018 Dec 13. ACS Infect Dis. 2019. PMID: 30543391 Free article.
The Pandemic Response Box─Accelerating Drug Discovery Efforts after Disease Outbreaks.
Samby K, Besson D, Dutta A, Patra B, Doy A, Glossop P, Mills J, Whitlock G, Hooft van Huijsduijnen R, Monaco A, Bilbe G, Mowbray C, Perry B, Adam A, Wells TNC, Willis PA. Samby K, et al. ACS Infect Dis. 2022 Apr 8;8(4):713-720. doi: 10.1021/acsinfecdis.1c00527. Epub 2022 Mar 14. ACS Infect Dis. 2022. PMID: 35286809 Free PMC article.
Collaborative Virtual Screening Identifies a 2-Aryl-4-aminoquinazoline Series with Efficacy in an In Vivo Model of Trypanosoma cruzi Infection.
Tawaraishi T, Ochida A, Akao Y, Itono S, Kamaura M, Akther T, Shimada M, Canan S, Chowdhury S, Cao Y, Condroski K, Engkvist O, Francisco A, Ghosh S, Kaki R, Kelly JM, Kimura C, Kogej T, Nagaoka K, Naito A, Pairaudeau G, Radu C, Roberts I, Shum D, Watanabe NA, Xie H, Yonezawa S, Yoshida O, Yoshida R, Mowbray C, Perry B. Tawaraishi T, et al. J Med Chem. 2023 Jan 26;66(2):1221-1238. doi: 10.1021/acs.jmedchem.2c00775. Epub 2023 Jan 6. J Med Chem. 2023. PMID: 36607408 Free PMC article.
Recent Development of Visceral Leishmaniasis Treatments: Successes, Pitfalls, and Perspectives.
Alves F, Bilbe G, Blesson S, Goyal V, Monnerat S, Mowbray C, Muthoni Ouattara G, Pécoul B, Rijal S, Rode J, Solomos A, Strub-Wourgaft N, Wasunna M, Wells S, Zijlstra EE, Arana B, Alvar J. Alves F, et al. Clin Microbiol Rev. 2018 Aug 29;31(4):e00048-18. doi: 10.1128/CMR.00048-18. Print 2018 Oct. Clin Microbiol Rev. 2018. PMID: 30158301 Free PMC article. Review.
Novel benzoxaborole, nitroimidazole and aminopyrazoles with activity against experimental cutaneous leishmaniasis.
Van Bocxlaer K, Caridha D, Black C, Vesely B, Leed S, Sciotti RJ, Wijnant GJ, Yardley V, Braillard S, Mowbray CE, Ioset JR, Croft SL. Van Bocxlaer K, et al. Among authors: mowbray ce. Int J Parasitol Drugs Drug Resist. 2019 Dec;11:129-138. doi: 10.1016/j.ijpddr.2019.02.002. Epub 2019 Feb 26. Int J Parasitol Drugs Drug Resist. 2019. PMID: 30922847 Free PMC article.
Route map for the discovery and pre-clinical development of new drugs and treatments for cutaneous leishmaniasis.
Caridha D, Vesely B, van Bocxlaer K, Arana B, Mowbray CE, Rafati S, Uliana S, Reguera R, Kreishman-Deitrick M, Sciotti R, Buffet P, Croft SL. Caridha D, et al. Among authors: mowbray ce. Int J Parasitol Drugs Drug Resist. 2019 Dec;11:106-117. doi: 10.1016/j.ijpddr.2019.06.003. Epub 2019 Jun 20. Int J Parasitol Drugs Drug Resist. 2019. PMID: 31320296 Free PMC article. Review.
2-aminobenzimidazoles for leishmaniasis: From initial hit discovery to in vivo profiling.
Ferreira RAA, Junior COR, Martinez PDG, Koovits PJ, Soares BM, Ferreira LLG, Michelan-Duarte S, Chelucci RC, Andricopulo AD, Galuppo MK, Uliana SRB, Matheeussen A, Caljon G, Maes L, Campbell S, Kratz JM, Mowbray CE, Dias LC. Ferreira RAA, et al. Among authors: mowbray ce. PLoS Negl Trop Dis. 2021 Feb 22;15(2):e0009196. doi: 10.1371/journal.pntd.0009196. eCollection 2021 Feb. PLoS Negl Trop Dis. 2021. PMID: 33617566 Free PMC article.
DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis.
Mowbray CE, Braillard S, Glossop PA, Whitlock GA, Jacobs RT, Speake J, Pandi B, Nare B, Maes L, Yardley V, Freund Y, Wall RJ, Carvalho S, Bello D, Van den Kerkhof M, Caljon G, Gilbert IH, Corpas-Lopez V, Lukac I, Patterson S, Zuccotto F, Wyllie S. Mowbray CE, et al. J Med Chem. 2021 Nov 11;64(21):16159-16176. doi: 10.1021/acs.jmedchem.1c01437. Epub 2021 Oct 28. J Med Chem. 2021. PMID: 34711050 Free PMC article.
42 results