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Multiple unbiased approaches identify oxidosqualene cyclase as the molecular target of a promising anti-leishmanial.
Paradela LS, Wall RJ, Carvalho S, Chemi G, Corpas-Lopez V, Moynihan E, Bello D, Patterson S, Güther MLS, Fairlamb AH, Ferguson MAJ, Zuccotto F, Martin J, Gilbert IH, Wyllie S. Paradela LS, et al. Among authors: moynihan e. Cell Chem Biol. 2021 May 20;28(5):711-721.e8. doi: 10.1016/j.chembiol.2021.02.008. Epub 2021 Mar 9. Cell Chem Biol. 2021. PMID: 33691122 Free PMC article.
Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase.
Milne R, Wiedemar N, Corpas-Lopez V, Moynihan E, Wall RJ, Dawson A, Robinson DA, Shepherd SM, Smith RJ, Hallyburton I, Post JM, Dowers K, Torrie LS, Gilbert IH, Baragaña B, Patterson S, Wyllie S. Milne R, et al. Among authors: moynihan e. ACS Infect Dis. 2022 Sep 9;8(9):1962-1974. doi: 10.1021/acsinfecdis.2c00364. Epub 2022 Aug 29. ACS Infect Dis. 2022. PMID: 36037410 Free PMC article.
Inflammatory vaginitis in four B-cell suppressed women with Multiple Sclerosis.
Levine L, Son J, Yu A, Wesley S, De Jager PL, Moynihan E, Farber RS, Rosser M, Haque H, Riley CS. Levine L, et al. Among authors: moynihan e. Mult Scler Relat Disord. 2024 Feb;82:105387. doi: 10.1016/j.msard.2023.105387. Epub 2023 Dec 16. Mult Scler Relat Disord. 2024. PMID: 38134606
Click Pt(IV)-Carbohydrates Pro-Drugs for Treatment of Osteosarcoma.
Moynihan E, Bassi G, Ruffini A, Panseri S, Montesi M, Velasco-Torrijos T, Montagner D. Moynihan E, et al. Front Chem. 2021 Dec 7;9:795997. doi: 10.3389/fchem.2021.795997. eCollection 2021. Front Chem. 2021. PMID: 34950638 Free PMC article.
19 results