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Sugar-free approaches to cancer cell killing.
El Mjiyad N, Caro-Maldonado A, Ramírez-Peinado S, Muñoz-Pinedo C. El Mjiyad N, et al. Oncogene. 2011 Jan 20;30(3):253-64. doi: 10.1038/onc.2010.466. Epub 2010 Oct 25. Oncogene. 2011. PMID: 20972457 Review.
Measuring the Activation of Cell Death Pathways upon Inhibition of Metabolism.
Püschel F, Muñoz-Pinedo C. Püschel F, et al. Among authors: munoz pinedo c. Methods Mol Biol. 2019;1862:163-172. doi: 10.1007/978-1-4939-8769-6_12. Methods Mol Biol. 2019. PMID: 30315467
Exploiting tumor vulnerabilities: epigenetics, cancer metabolism and the mTOR pathway in the era of personalized medicine.
Muñoz-Pinedo C, González-Suárez E, Portela A, Gentilella A, Esteller M. Muñoz-Pinedo C, et al. Cancer Res. 2013 Jul 15;73(14):4185-9. doi: 10.1158/0008-5472.CAN-13-0512. Epub 2013 May 17. Cancer Res. 2013. PMID: 23687347
"(Not) all (dead) things share the same breath": identification of cell death mechanisms in anticancer therapy.
Rello-Varona S, Herrero-Martín D, López-Alemany R, Muñoz-Pinedo C, Tirado OM. Rello-Varona S, et al. Cancer Res. 2015 Mar 15;75(6):913-7. doi: 10.1158/0008-5472.CAN-14-3494. Epub 2015 Feb 27. Cancer Res. 2015. PMID: 25724677 Review.
Glucose-starved cells do not engage in prosurvival autophagy.
Ramírez-Peinado S, León-Annicchiarico CL, Galindo-Moreno J, Iurlaro R, Caro-Maldonado A, Prehn JH, Ryan KM, Muñoz-Pinedo C. Ramírez-Peinado S, et al. J Biol Chem. 2013 Oct 18;288(42):30387-98. doi: 10.1074/jbc.M113.490581. Epub 2013 Sep 6. J Biol Chem. 2013. PMID: 24014036 Free PMC article.
Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy.
López-Erauskin J, Galino J, Bianchi P, Fourcade S, Andreu AL, Ferrer I, Muñoz-Pinedo C, Pujol A. López-Erauskin J, et al. Brain. 2012 Dec;135(Pt 12):3584-98. doi: 10.1093/brain/aws292. Brain. 2012. PMID: 23250880 Free PMC article.
2-deoxyglucose induces Noxa-dependent apoptosis in alveolar rhabdomyosarcoma.
Ramírez-Peinado S, Alcázar-Limones F, Lagares-Tena L, El Mjiyad N, Caro-Maldonado A, Tirado OM, Muñoz-Pinedo C. Ramírez-Peinado S, et al. Cancer Res. 2011 Nov 1;71(21):6796-806. doi: 10.1158/0008-5472.CAN-11-0759. Epub 2011 Sep 12. Cancer Res. 2011. PMID: 21911456
A role for caspase-8 and TRAIL-R2/DR5 in ER-stress-induced apoptosis.
Muñoz-Pinedo C, López-Rivas A. Muñoz-Pinedo C, et al. Cell Death Differ. 2018 Jan;25(1):226. doi: 10.1038/cdd.2017.155. Epub 2017 Oct 6. Cell Death Differ. 2018. PMID: 28984868 Free PMC article. No abstract available.
Combining 2-deoxy-D-glucose with fenofibrate leads to tumor cell death mediated by simultaneous induction of energy and ER stress.
Liu H, Kurtoglu M, León-Annicchiarico CL, Munoz-Pinedo C, Barredo J, Leclerc G, Merchan J, Liu X, Lampidis TJ. Liu H, et al. Oncotarget. 2016 Jun 14;7(24):36461-36473. doi: 10.18632/oncotarget.9263. Oncotarget. 2016. PMID: 27183907 Free PMC article.
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