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The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes.
Parkinson A, Mudra DR, Johnson C, Dwyer A, Carroll KM. Parkinson A, et al. Among authors: mudra dr. Toxicol Appl Pharmacol. 2004 Sep 15;199(3):193-209. doi: 10.1016/j.taap.2004.01.010. Toxicol Appl Pharmacol. 2004. PMID: 15364537 Review.
Analysis of CYP mRNA expression by branched DNA technology.
Czerwinski M, Opdam P, Madan A, Carroll K, Mudra DR, Gan LL, Luo G, Parkinson A. Czerwinski M, et al. Among authors: mudra dr. Methods Enzymol. 2002;357:170-9. doi: 10.1016/s0076-6879(02)57676-x. Methods Enzymol. 2002. PMID: 12424908 No abstract available.
Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes.
Madan A, Graham RA, Carroll KM, Mudra DR, Burton LA, Krueger LA, Downey AD, Czerwinski M, Forster J, Ribadeneira MD, Gan LS, LeCluyse EL, Zech K, Robertson P Jr, Koch P, Antonian L, Wagner G, Yu L, Parkinson A. Madan A, et al. Among authors: mudra dr. Drug Metab Dispos. 2003 Apr;31(4):421-31. doi: 10.1124/dmd.31.4.421. Drug Metab Dispos. 2003. PMID: 12642468
The effect of fenbuconazole on cell proliferation and enzyme induction in the liver of female CD1 mice.
Juberg DR, Mudra DR, Hazelton GA, Parkinson A. Juberg DR, et al. Among authors: mudra dr. Toxicol Appl Pharmacol. 2006 Jul 15;214(2):178-87. doi: 10.1016/j.taap.2006.01.017. Epub 2006 Mar 20. Toxicol Appl Pharmacol. 2006. PMID: 16542693
Effect of cryopreservation on cytochrome P-450 enzyme induction in cultured rat hepatocytes.
Madan A, DeHaan R, Mudra D, Carroll K, LeCluyse E, Parkinson A. Madan A, et al. Drug Metab Dispos. 1999 Mar;27(3):327-35. Drug Metab Dispos. 1999. PMID: 10064562
CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes.
Luo G, Cunningham M, Kim S, Burn T, Lin J, Sinz M, Hamilton G, Rizzo C, Jolley S, Gilbert D, Downey A, Mudra D, Graham R, Carroll K, Xie J, Madan A, Parkinson A, Christ D, Selling B, LeCluyse E, Gan LS. Luo G, et al. Drug Metab Dispos. 2002 Jul;30(7):795-804. doi: 10.1124/dmd.30.7.795. Drug Metab Dispos. 2002. PMID: 12065438
Preparation of hepatocytes.
Mudra DR, Parkinson A. Mudra DR, et al. Curr Protoc Toxicol. 2001 Aug;Chapter 14:Unit 14.2. doi: 10.1002/0471140856.tx1402s08. Curr Protoc Toxicol. 2001. PMID: 23045038
In vivo and in vitro induction of cytochrome P450 enzymes in beagle dogs.
Graham RA, Downey A, Mudra D, Krueger L, Carroll K, Chengelis C, Madan A, Parkinson A. Graham RA, et al. Drug Metab Dispos. 2002 Nov;30(11):1206-13. doi: 10.1124/dmd.30.11.1206. Drug Metab Dispos. 2002. PMID: 12386126
In silico, in vitro and in situ models to assess interplay between CYP3A and P-gp.
Mudra DR, Desino KE, Desai PV. Mudra DR, et al. Curr Drug Metab. 2011 Oct;12(8):750-73. doi: 10.2174/138920011798356999. Curr Drug Metab. 2011. PMID: 21568936 Review.
Translational pharmacokinetic-pharmacodynamic analysis in the pharmaceutical industry: an IQ Consortium PK-PD Discussion Group perspective.
Wong H, Bohnert T, Damian-Iordache V, Gibson C, Hsu CP, Krishnatry AS, Liederer BM, Lin J, Lu Q, Mettetal JT, Mudra DR, Nijsen MJMA, Schroeder P, Schuck E, Suryawanshi S, Trapa P, Tsai A, Wang H, Wu F. Wong H, et al. Among authors: mudra dr. Drug Discov Today. 2017 Oct;22(10):1447-1459. doi: 10.1016/j.drudis.2017.04.015. Epub 2017 May 2. Drug Discov Today. 2017. PMID: 28476536 Review.
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