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Design and Synthesis of a Pan-Janus Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin.
Jones P, Storer RI, Sabnis YA, Wakenhut FM, Whitlock GA, England KS, Mukaiyama T, Dehnhardt CM, Coe JW, Kortum SW, Chrencik JE, Brown DG, Jones RM, Murphy JR, Yeoh T, Morgan P, Kilty I. Jones P, et al. Among authors: mukaiyama t. J Med Chem. 2017 Jan 26;60(2):767-786. doi: 10.1021/acs.jmedchem.6b01634. Epub 2017 Jan 4. J Med Chem. 2017. PMID: 27983835
Optimisation of a novel series of selective CNS penetrant CB(2) agonists.
Watson C, Owen DR, Harding D, Kon-I K, Lewis ML, Mason HJ, Matsumizu M, Mukaiyama T, Rodriguez-Lens M, Shima A, Takeuchi M, Tran I, Young T. Watson C, et al. Among authors: mukaiyama t. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4284-7. doi: 10.1016/j.bmcl.2011.05.063. Epub 2011 May 25. Bioorg Med Chem Lett. 2011. PMID: 21669533
Asymmetric total synthesis of pseurotin A.
Hayashi Y, Shoji M, Yamaguchi S, Mukaiyama T, Yamaguchi J, Kakeya H, Osada H. Hayashi Y, et al. Among authors: mukaiyama t. Org Lett. 2003 Jun 26;5(13):2287-90. doi: 10.1021/ol034630s. Org Lett. 2003. PMID: 12816430
122 results