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The PE/PPE multigene family codes for virulence factors and is a possible source of mycobacterial antigenic variation: perhaps more?
Akhter Y, Ehebauer MT, Mukhopadhyay S, Hasnain SE. Akhter Y, et al. Among authors: mukhopadhyay s. Biochimie. 2012 Jan;94(1):110-6. doi: 10.1016/j.biochi.2011.09.026. Epub 2011 Oct 12. Biochimie. 2012. PMID: 22005451 Review.
PPE antigen Rv2430c of Mycobacterium tuberculosis induces a strong B-cell response.
Choudhary RK, Mukhopadhyay S, Chakhaiyar P, Sharma N, Murthy KJ, Katoch VM, Hasnain SE. Choudhary RK, et al. Among authors: mukhopadhyay s. Infect Immun. 2003 Nov;71(11):6338-43. doi: 10.1128/iai.71.11.6338-6343.2003. Infect Immun. 2003. PMID: 14573653 Free PMC article.
The PE and PPE proteins of Mycobacterium tuberculosis.
Mukhopadhyay S, Balaji KN. Mukhopadhyay S, et al. Tuberculosis (Edinb). 2011 Sep;91(5):441-7. doi: 10.1016/j.tube.2011.04.004. Epub 2011 May 6. Tuberculosis (Edinb). 2011. PMID: 21527209 Review.
In this perspective, identification of the mycobacterial components that have important role(s) in the establishment of the infection assumes crucial importance. ...
In this perspective, identification of the mycobacterial components that have important role(s) in the establishment of the infection …
Pathogenesis in tuberculosis: transcriptomic approaches to unraveling virulence mechanisms and finding new drug targets.
Mukhopadhyay S, Nair S, Ghosh S. Mukhopadhyay S, et al. FEMS Microbiol Rev. 2012 Mar;36(2):463-85. doi: 10.1111/j.1574-6976.2011.00302.x. Epub 2011 Sep 15. FEMS Microbiol Rev. 2012. PMID: 22092372 Review.
Proline-proline-glutamic acid (PPE) protein Rv1168c of Mycobacterium tuberculosis augments transcription from HIV-1 long terminal repeat promoter.
Bhat KH, Chaitanya CK, Parveen N, Varman R, Ghosh S, Mukhopadhyay S. Bhat KH, et al. Among authors: mukhopadhyay s. J Biol Chem. 2012 May 11;287(20):16930-46. doi: 10.1074/jbc.M111.327825. Epub 2012 Mar 15. J Biol Chem. 2012. PMID: 22427668 Free PMC article.
The occurrence of HIV type 1 (HIV-1) infection is found to be accelerated in people infected with Mycobacterium tuberculosis, but the mechanism by which mycobacterial protein(s) induces HIV-1 LTR trans-activation is not clearly understood. ...
The occurrence of HIV type 1 (HIV-1) infection is found to be accelerated in people infected with Mycobacterium tuberculosis, but the mechan …
Mycobacterium tuberculosis PPE protein Rv0256c induces strong B cell response in tuberculosis patients.
Abraham PR, Latha GS, Valluri VL, Mukhopadhyay S. Abraham PR, et al. Among authors: mukhopadhyay s. Infect Genet Evol. 2014 Mar;22:244-9. doi: 10.1016/j.meegid.2013.06.023. Epub 2013 Jul 2. Infect Genet Evol. 2014. PMID: 23827809
The ESAT-6 protein of Mycobacterium tuberculosis interacts with beta-2-microglobulin (β2M) affecting antigen presentation function of macrophage.
Sreejit G, Ahmed A, Parveen N, Jha V, Valluri VL, Ghosh S, Mukhopadhyay S. Sreejit G, et al. Among authors: mukhopadhyay s. PLoS Pathog. 2014 Oct 30;10(10):e1004446. doi: 10.1371/journal.ppat.1004446. eCollection 2014 Oct. PLoS Pathog. 2014. PMID: 25356553 Free PMC article.
Immunoregulatory functions and expression patterns of PE/PPE family members: Roles in pathogenicity and impact on anti-tuberculosis vaccine and drug design.
Ahmed A, Das A, Mukhopadhyay S. Ahmed A, et al. Among authors: mukhopadhyay s. IUBMB Life. 2015 Jun;67(6):414-27. doi: 10.1002/iub.1387. Epub 2015 Jun 24. IUBMB Life. 2015. PMID: 26104967 Review.
PE11, a PE/PPE family protein of Mycobacterium tuberculosis is involved in cell wall remodeling and virulence.
Singh P, Rao RN, Reddy JR, Prasad RB, Kotturu SK, Ghosh S, Mukhopadhyay S. Singh P, et al. Among authors: mukhopadhyay s. Sci Rep. 2016 Feb 23;6:21624. doi: 10.1038/srep21624. Sci Rep. 2016. PMID: 26902658 Free PMC article.
Transduction of Functionally Contrasting Signals by Two Mycobacterial PPE Proteins Downstream of TLR2 Receptors.
Udgata A, Qureshi R, Mukhopadhyay S. Udgata A, et al. Among authors: mukhopadhyay s. J Immunol. 2016 Sep 1;197(5):1776-87. doi: 10.4049/jimmunol.1501816. Epub 2016 Aug 1. J Immunol. 2016. PMID: 27481848
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