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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1978 2
1981 3
1982 2
1983 3
1984 6
1986 2
1987 2
1988 2
1989 6
1990 7
1991 8
1992 14
1993 11
1994 18
1995 14
1996 14
1997 20
1998 13
1999 17
2000 32
2001 26
2002 27
2003 30
2004 24
2005 29
2006 35
2007 29
2008 38
2009 41
2010 48
2011 58
2012 58
2013 51
2014 56
2015 51
2016 59
2017 60
2018 59
2019 45
2020 72
2021 70
2022 40
2023 32
2024 8

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1,126 results

Results by year

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Page 1
Multiple sclerosis progression: time for a new mechanism-driven framework.
Kuhlmann T, Moccia M, Coetzee T, Cohen JA, Correale J, Graves J, Marrie RA, Montalban X, Yong VW, Thompson AJ, Reich DS; International Advisory Committee on Clinical Trials in Multiple Sclerosis. Kuhlmann T, et al. Lancet Neurol. 2023 Jan;22(1):78-88. doi: 10.1016/S1474-4422(22)00289-7. Epub 2022 Nov 18. Lancet Neurol. 2023. PMID: 36410373 Free PMC article. Review.
Traditionally, multiple sclerosis has been categorised by distinct clinical descriptors-relapsing-remitting, secondary progressive, and primary progressive-for patient care, research, and regulatory approval of medications. Accumulating evidence suggests that the cl …
Traditionally, multiple sclerosis has been categorised by distinct clinical descriptors-relapsing-remitting, secondary progres …
Multiple Sclerosis: Mechanisms and Immunotherapy.
Baecher-Allan C, Kaskow BJ, Weiner HL. Baecher-Allan C, et al. Neuron. 2018 Feb 21;97(4):742-768. doi: 10.1016/j.neuron.2018.01.021. Neuron. 2018. PMID: 29470968 Free article. Review.
Multiple sclerosis (MS) is an autoimmune disease triggered by environmental factors that act on a genetically susceptible host. ...Major challenges for MS research involve understanding the mechanisms of disease progression, developing treatment
Multiple sclerosis (MS) is an autoimmune disease triggered by environmental factors that act on a genetically suscep
Lifestyle and Environmental Factors in Multiple Sclerosis.
Alfredsson L, Olsson T. Alfredsson L, et al. Cold Spring Harb Perspect Med. 2019 Apr 1;9(4):a028944. doi: 10.1101/cshperspect.a028944. Cold Spring Harb Perspect Med. 2019. PMID: 29735578 Free PMC article. Review.
Lifestyle and environmental factors potently influence the risk of multiple sclerosis (MS), because genetic predisposition only explains a fraction of the risk increase. ...
Lifestyle and environmental factors potently influence the risk of multiple sclerosis (MS), because genetic predisposition onl …
Immunopathology of multiple sclerosis.
Dendrou CA, Fugger L, Friese MA. Dendrou CA, et al. Nat Rev Immunol. 2015 Sep 15;15(9):545-58. doi: 10.1038/nri3871. Epub 2015 Aug 7. Nat Rev Immunol. 2015. PMID: 26250739 Review.
Two decades of clinical experience with immunomodulatory treatments for multiple sclerosis point to distinct immunological pathways that drive disease relapses and progression. In light of this, we discuss our current understanding of multiple scler
Two decades of clinical experience with immunomodulatory treatments for multiple sclerosis point to distinct immunological pat …
Multiple sclerosis: genetics, biomarkers, treatments.
Axisa PP, Hafler DA. Axisa PP, et al. Curr Opin Neurol. 2016 Jun;29(3):345-53. doi: 10.1097/WCO.0000000000000319. Curr Opin Neurol. 2016. PMID: 27058221 Free PMC article. Review.
SUMMARY: Breakthroughs in the field of multiple sclerosis have led to a better understanding of the physiopathology of the disease, follow up, and treatment of the patients that develop relapsing remitting multiple sclerosis. The next challenge …
SUMMARY: Breakthroughs in the field of multiple sclerosis have led to a better understanding of the physiopathology of the …
Interactions between genetic, lifestyle and environmental risk factors for multiple sclerosis.
Olsson T, Barcellos LF, Alfredsson L. Olsson T, et al. Nat Rev Neurol. 2017 Jan;13(1):25-36. doi: 10.1038/nrneurol.2016.187. Epub 2016 Dec 9. Nat Rev Neurol. 2017. PMID: 27934854 Review.
Genetic predisposition to multiple sclerosis (MS) only explains a fraction of the disease risk; lifestyle and environmental factors are key contributors to the risk of MS. ...Organic solvents and shift work have also been reported to confer increased risk of …
Genetic predisposition to multiple sclerosis (MS) only explains a fraction of the disease risk; lifestyle and environme …
Epstein-Barr virus as a cause of multiple sclerosis: opportunities for prevention and therapy.
Aloisi F, Giovannoni G, Salvetti M. Aloisi F, et al. Lancet Neurol. 2023 Apr;22(4):338-349. doi: 10.1016/S1474-4422(22)00471-9. Epub 2023 Feb 7. Lancet Neurol. 2023. PMID: 36764322 Review.
Multiple sclerosis is a chronic inflammatory disease of the CNS that results from the interplay between heritable and environmental factors. ...If EBV also has a role in driving disease activity, the characterisation of this role will help diagnosis, p
Multiple sclerosis is a chronic inflammatory disease of the CNS that results from the interplay between heritable and e
Resolution of inflammation during multiple sclerosis.
Ruiz F, Vigne S, Pot C. Ruiz F, et al. Semin Immunopathol. 2019 Nov;41(6):711-726. doi: 10.1007/s00281-019-00765-0. Epub 2019 Nov 15. Semin Immunopathol. 2019. PMID: 31732775 Free PMC article. Review.
Multiple sclerosis (MS) is a frequent autoimmune demyelinating disease of the central nervous system (CNS). There are three clinical forms described: relapsing-remitting multiple sclerosis (RRMS), the most common initial presentation (85%) among
Multiple sclerosis (MS) is a frequent autoimmune demyelinating disease of the central nervous system (CNS). There are t
Microglia in Multiple Sclerosis: Friend or Foe?
Guerrero BL, Sicotte NL. Guerrero BL, et al. Front Immunol. 2020 Mar 20;11:374. doi: 10.3389/fimmu.2020.00374. eCollection 2020. Front Immunol. 2020. PMID: 32265902 Free PMC article. Review.
Microglia originate from myeloid progenitors in the embryonic yolk sac and play an integral role in central nervous system (CNS) development, immune surveillance and repair. The role of microglia in multiple sclerosis (MS) has been complex and controversial, with ev …
Microglia originate from myeloid progenitors in the embryonic yolk sac and play an integral role in central nervous system (CNS) development …
Epidemiology of Multiple Sclerosis: From Risk Factors to Prevention-An Update.
Ascherio A, Munger KL. Ascherio A, et al. Semin Neurol. 2016 Apr;36(2):103-14. doi: 10.1055/s-0036-1579693. Epub 2016 Apr 26. Semin Neurol. 2016. PMID: 27116717 Review.
Although genetic susceptibility explains the clustering of multiple sclerosis (MS) within families and the sharp decline in risk with increasing genetic distance, it cannot fully explain the geographical variations in MS frequency and the changes in risk that …
Although genetic susceptibility explains the clustering of multiple sclerosis (MS) within families and the sharp declin …
1,126 results