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Notch signaling: from the outside in.
Mumm JS, Kopan R. Mumm JS, et al. Dev Biol. 2000 Dec 15;228(2):151-65. doi: 10.1006/dbio.2000.9960. Dev Biol. 2000. PMID: 11112321 Review. No abstract available.
Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis.
Saxena MT, Schroeter EH, Mumm JS, Kopan R. Saxena MT, et al. J Biol Chem. 2001 Oct 26;276(43):40268-73. doi: 10.1074/jbc.M107234200. Epub 2001 Aug 22. J Biol Chem. 2001. PMID: 11518718
A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.
De Strooper B, Annaert W, Cupers P, Saftig P, Craessaerts K, Mumm JS, Schroeter EH, Schrijvers V, Wolfe MS, Ray WJ, Goate A, Kopan R. De Strooper B, et al. Nature. 1999 Apr 8;398(6727):518-22. doi: 10.1038/19083. Nature. 1999. PMID: 10206645
Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.
Huppert SS, Le A, Schroeter EH, Mumm JS, Saxena MT, Milner LA, Kopan R. Huppert SS, et al. Nature. 2000 Jun 22;405(6789):966-70. doi: 10.1038/35016111. Nature. 2000. PMID: 10879540
Evidence for a physical interaction between presenilin and Notch.
Ray WJ, Yao M, Nowotny P, Mumm J, Zhang W, Wu JY, Kopan R, Goate AM. Ray WJ, et al. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3263-8. doi: 10.1073/pnas.96.6.3263. Proc Natl Acad Sci U S A. 1999. PMID: 10077672 Free PMC article.
Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch.
Ray WJ, Yao M, Mumm J, Schroeter EH, Saftig P, Wolfe M, Selkoe DJ, Kopan R, Goate AM. Ray WJ, et al. J Biol Chem. 1999 Dec 17;274(51):36801-7. doi: 10.1074/jbc.274.51.36801. J Biol Chem. 1999. PMID: 10593990
Rapid adaptive optical recovery of optimal resolution over large volumes.
Wang K, Milkie DE, Saxena A, Engerer P, Misgeld T, Bronner ME, Mumm J, Betzig E. Wang K, et al. Nat Methods. 2014 Jun;11(6):625-8. doi: 10.1038/nmeth.2925. Epub 2014 Apr 13. Nat Methods. 2014. PMID: 24727653 Free PMC article.
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